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瘦子也会得脂肪肝,后果比胖子更严重!

2016-12-21 二刀 青年健康新视点

瘦子也会得脂肪肝?脂肪肝,顾名思义,就是指各种原因引起的肝细胞内脂肪堆积过多的病变。看到这儿,许多人会想,既然要脂肪堆积,是不是意味着脂肪肝只会在肥胖的人群中才有啊,正常体重甚至偏瘦的人应该就不会和它有什么瓜葛了吧?­很遗憾,事实并非如此。一般而言,脂肪肝可以分为酒精性脂肪肝和非酒精性脂肪肝两大类,而这两种情况都没有排除瘦子患病的可能性。瘦子和酒精性脂肪肝酒精性脂肪肝是由于长期大量饮酒导致的肝脏疾

瘦子也会得脂肪肝?


脂肪肝,顾名思义,就是指各种原因引起的肝细胞内脂肪堆积过多的病变。看到这儿,许多人会想,既然要脂肪堆积,是不是意味着脂肪肝只会在肥胖的人群中才有啊,正常体重甚至偏瘦的人应该就不会和它有什么瓜葛了吧?­


很遗憾,事实并非如此。


一般而言,脂肪肝可以分为酒精性脂肪肝和非酒精性脂肪肝两大类,而这两种情况都没有排除瘦子患病的可能性。




瘦子和酒精性脂肪肝


酒精性脂肪肝是由于长期大量饮酒导致的肝脏疾病,通常酒精性脂肪肝的发病和长期的饮酒有着必然的联系,和患者是否体重超标没有明显的关系。


酒精导致脂肪肝的原因很复杂,其中最主要的原因是大量的酒精会直接损伤肝脏细胞。实际上,我们饮用的酒精90%是在肝脏内代谢,长期大量的摄入酒精能使肝内脂肪酸代谢发生障碍,形成脂肪堆积、变性,最终导致脂肪肝的形成。




脂肪肝患者通常表现为一些非特异症状,意思就是看上去并没有特别指向某一个病的一些症状,包括右上腹胀痛、食欲不振、乏力、体重减轻等,因此瘦子(不管是本身偏瘦还是因疾病而消瘦)实际上也有可能患上这种类型的脂肪肝。


当然酒精肝的预后一般较为好,只需要戒酒治疗就可以完全恢复,但是如果情况严重则需要进一步的处理,防止疾病发展成酒精性肝炎甚至肝硬化。


瘦子和非酒精性脂肪肝


我们通常认为非酒精性脂肪肝与肥胖有着密切的因果关系,但是近年来的研究表明:正常体重者或者偏瘦者,同样也不能够排除患病的可能性。


通过美国、日本、韩国、香港、印度等研究,非酒精性脂肪肝患者中至少有10%是瘦子,在有些研究中,这个比例甚至达到了接近20%。


而且,一旦偏瘦又不幸患上脂肪肝,相比于肥胖相关的脂肪肝患者,可能肝脏功能与结构将会有更严重的病变,导致更严重的后果。


这好像不可思议,却是经过许多研究证明了的事。


瘦子得了非酒精性脂肪肝,后果比胖子更严重




一项研究了30172名受试者的研究认为,年轻的非肥胖型非酒精性脂肪肝患者有更高的几率患心血管疾病,从而造成更高的死亡率。


而另一项研究则发现,在非酒精性脂肪肝患者中,非肥胖者的病理活检中能够发现更多更严重的肝脏组织细胞炎症情况以及更高的死亡率。消瘦者有更高的代谢性疾病(比如糖尿病)患病率和更严重的肝硬化患病率。


由此我们可以看出,在非酒精性脂肪肝患者中,偏瘦者相对于肥胖者往往更危险,疾病结局更糟糕。


所以,偏瘦者更不应该忽视脂肪肝的存在,更应该高度重视,及早发现,积极干预,这样才能更好的应对更严重的威胁。


可是,为什么瘦子也患非酒精性脂肪肝呢?


现有的研究倾向于关注与遗传因素和环境因素对偏瘦者患非酒精性脂肪肝的影响,但是遗憾的是,迄今为止,其病理生理学基础还没有完全阐释清楚,许多研究结果也是互相打脸,乐此不疲。


这可能是因为造成这种脂肪肝分型的途径并非只有一条,而是多种因素、多种途径共同作用的结果。


一般而言,这些疾病的影响因素包括两大类,遗传感染性(代谢疾病和胰岛素抵抗)与环境因素(童年营养状态、生活方式、饮食结构、肠道菌群等)。


瘦子脂肪肝咋办?


如果肥胖的人患了脂肪肝,“减肥”这个治疗建议几乎是一定会出现的。那么瘦子该怎么办呢?


虽然瘦子不用减肥,但是调整生活方式、规律作息、规律吃饭、避免过度劳累这些方法一样是好用的。再来,注意饮食结构,健康饮食,减少红肉摄入,多吃蔬菜等等,如果经济条件允许,可以尝试一下点哥曾经推荐过的“地中海饮食”结构。


除了这些,脂肪肝患者需要定期体检和随访,以便医生给出适宜的治疗方案。


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    2018-10-15 1e145228m78(暂无匿称)

    学习了,谢谢作者分享!

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    2016-12-23 虈亣靌

    很有帮助,谢谢分享

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    2016-12-22 1e0c1443m21(暂无匿称)

    身体贵在保养

    0

  4. [GetPortalCommentsPageByObjectIdResponse(id=349457, encodeId=bc1134945ef4, content=学习了,谢谢作者分享!, beContent=null, objectType=article, channel=null, level=null, likeNumber=92, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/mONcle9pic3xJXLtMtt5B40XXuPjn9xn1rBhrM6fHLkX1hI86ZoWoPJkgDkZuJNKkBfBHOcRd1fAdezg7JlHNOokohdAp3WkI/0, createdBy=32c81964262, createdName=1e145228m78(暂无匿称), createdTime=Mon Oct 15 22:01:43 CST 2018, time=2018-10-15, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=165129, encodeId=96ad1651296c, content=很有帮助,谢谢分享, beContent=null, objectType=article, channel=null, level=null, likeNumber=114, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/mONcle9pic3zMoyicyo6ia9f4IuLQAwZoxD6Hx4ibd5CMcOCYhStY6oDibbKK6O2X8iaicldO5ib8j1iapOIobIKCGiczU2A/0, createdBy=56251941490, createdName=虈亣靌, createdTime=Fri Dec 23 13:10:48 CST 2016, time=2016-12-23, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=164911, encodeId=a8bc1649110c, content=身体贵在保养, beContent=null, objectType=article, channel=null, level=null, likeNumber=87, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/oLAjfB7s1ib3ibz8CYT5b0zyDiasBqB9iaBNmoAnltag9pJoPmiacnibTMS4y6wnSXsibl2wHn1fed1RMiaF3elh76pbNP1j2LiaSks8S/0, createdBy=09681927734, createdName=1e0c1443m21(暂无匿称), createdTime=Thu Dec 22 15:47:01 CST 2016, time=2016-12-22, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=164772, encodeId=c85a164e726e, content=喝酒坏处多, beContent=null, objectType=article, channel=null, level=null, likeNumber=96, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=2e9c1996425, createdName=SAd, createdTime=Thu Dec 22 06:27:35 CST 2016, time=2016-12-22, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=164728, encodeId=3637164e2822, content=瘦子也会得脂肪肝,后果比胖子更严重!, beContent=null, objectType=article, channel=null, level=null, likeNumber=94, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/mStl88fu4NfNLvzZhgPxRrYOibkVibW9vAkCfb2F55aHjqMoqUVaF9fuXIMCxexawSOsicpbF7Ria7o54zPK65PodlkwhPrNhLhS/0, createdBy=12f71314239, createdName=ann y, createdTime=Wed Dec 21 22:13:50 CST 2016, time=2016-12-21, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=164727, encodeId=f61c164e2758, content=瘦子也会得脂肪肝,后果比胖子更严重!, beContent=null, objectType=article, channel=null, level=null, likeNumber=127, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/mStl88fu4NfNLvzZhgPxRrYOibkVibW9vAkCfb2F55aHjqMoqUVaF9fuXIMCxexawSOsicpbF7Ria7o54zPK65PodlkwhPrNhLhS/0, createdBy=12f71314239, createdName=ann y, createdTime=Wed Dec 21 22:13:42 CST 2016, time=2016-12-21, status=1, ipAttribution=)]
    2016-12-22 SAd

    喝酒坏处多

    0

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    2016-12-21 ann y

    瘦子也会得脂肪肝,后果比胖子更严重!

    0

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    2016-12-21 ann y

    瘦子也会得脂肪肝,后果比胖子更严重!

    0

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