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中药西药合用,切记15大禁忌 !

2016-05-18 佚名 药评中心

据统计,五分之三以上的中成药由西医师开具,中西药联用十分普遍。中西药配伍合理,可提高疗效,或减少毒副作用;配伍不合理,则会导致药效降低,或使毒副反应增加。总结中西药联用15大禁忌,供医师和药师参考。1药效相似的中西药合用1.中药麻黄、桂枝等解表发汗药,与扑热息痛、阿司匹林、布洛芬等解热镇痛药合用。●不良反应:发汗过多,引起虚脱;血液粘稠度增加,引起血压升高、心绞痛等。2.含麻黄的中成药,与洋地黄类

据统计,五分之三以上的中成药由西医师开具,中西药联用十分普遍。中西药配伍合理,可提高疗效,或减少毒副作用;配伍不合理,则会导致药效降低,或使毒副反应增加。总结中西药联用15大禁忌,供医师和药师参考。

1药效相似的中西药合用

1.中药麻黄、桂枝等解表发汗药,与扑热息痛、阿司匹林、布洛芬等解热镇痛药合用。

●不良反应:发汗过多,引起虚脱;血液粘稠度增加,引起血压升高、心绞痛等。

2.含麻黄的中成药,与洋地黄类强心甙如地高辛、西地兰等合用。

●不良反应:麻黄中所含的麻黄碱能加强心肌收缩力,增强强心甙的作用,引发心率失常。

3.含麻黄的中成药,不宜与氨茶碱同用。

●不良反应:有协同平喘作用,而毒性增加,可产生头痛、头昏、心率失常等,故合用时宜减少剂量。

4. 蟾酥、罗布麻、夹竹桃等含强心甙成分的中药,与洋地黄类强心甙合用。

●不良反应:易引发洋地黄中毒,应避免合用。

5.中药石决明、石膏、瓦楞子、龙骨、牡蛎等含钙离子的中药,与强心甙合用。

●不良反应:增加强心甙毒性。

6.六神丸、麝香保心丸、益心丸等中成药,与心律平、奎尼丁同服。

●不良反应:合用可使心跳骤停而发生危险。

7.含甘草次酸的中成药,如快胃片、补中益气丸、逍遥丸、香砂养胃丸、十全大补丸、人参当归丸、牛黄上清丸、安神补脑液、复方甘草合剂,以及具有肾上腺皮质激素样作用的中成药,如鹿茸等,与激素类、水杨酸类衍生物长期合用;与利尿酸、氢氯噻嗪等排钾利尿药联用;与洋地黄类强心甙合用。

●不良反应:均具有胃肠道刺激性,增加胃肠溃疡的发病率;与利尿药同用,容易诱发低血钾;与洋地黄类强心甙合用,能使体内钾离子浓度降低,导致心脏对强心甙的敏感性增高而引起中毒。

2药效相反的药物合用

8.含麻黄的中成药与催眠剂同用

●不良反应:有中枢兴奋作用的麻黄碱可减缓催眠药的作用。

9.含麻黄的中成药与氯丙嗪合用

●不良反应:可使血压下降过低。

10.含淀粉酶较多的六曲、麦芽组成的中成药(复方青黛丸、脑立清、小儿至宝丸等)与抗生素(尤其是口服抗生素)、水杨酸钠、阿司匹林、烟酸并用。

●不良反应:可降低淀粉酶的活性。如必须联用,至少要间隔2小时。

11.含甘草的中成药及含鹿茸的制剂(如健脑补肾丸、乳癖消、鹿胎膏、参茸安神丸等)与降血糖药胰岛素、格列本脲、苯乙双胍、甲苯磺丁脲等合用。

●不良反应:因前者可引起血糖上升,抵消降糖药的部分降糖作用,不利于糖尿病的治疗。

3合用会增加毒副作用的药物

12.含桃仁、苦杏仁、银杏、枇杷仁等组成的中成药,与麻醉药、镇静催眠药、止咳药如可待因、吗啡、杜冷丁、阿片制剂、苯巴比妥、利眠宁、安定等联用。

●不良反应:它们合用会引起呼吸中枢抑制甚至呼吸衰竭,并损害肝功能。合用时应注意,密切观察病情。

13.雷公藤与氯霉素长期合用。

●不良反应:两者都能抑制骨髓造血机能,可引起白细胞减少,产生血小板减少性紫癜。

14.含牛黄的中成药与苯巴比妥、吗啡、水合氯醛等中枢抑制药物合用。

●不良反应:因牛黄会增加对中枢的抑制作用,故西药应减量服用。

15.大活络丹、九分散、半夏露冲剂等含麻黄的中成药与呋喃唑酮、苯乙肼等单胺氧化酶抑制剂合用。

●不良反应:两者合用可能导致高血压危象和脑溢血。

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  1. [GetPortalCommentsPageByObjectIdResponse(id=106626, encodeId=854f106626f0, content=深度好文,值得学习,赞!, beContent=null, objectType=article, channel=null, level=null, likeNumber=93, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/NUyjXTCJjo7s7ZCKOmmbBTD6nE7gcd5OZpvyGEzkxBP3S275k5ZJVrsPkotZhBglRHM9rKvcj1OgkssqhcnoPw8zIaMZTF8c/0, createdBy=4c441942088, createdName=ylzr123, createdTime=Mon Aug 29 07:54:00 CST 2016, time=2016-08-29, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=86668, encodeId=cb9a86668c6, content=这样的文章要多学, beContent=null, objectType=article, channel=null, level=null, likeNumber=143, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=20751724934, createdName=QQ76174b26, createdTime=Fri May 20 09:38:00 CST 2016, time=2016-05-20, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1545078, encodeId=d77d15450e8a9, content=<a href='/topic/show?id=b7abe4635e0' target=_blank style='color:#2F92EE;'>#禁忌#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=67, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=74635, encryptionId=b7abe4635e0, topicName=禁忌)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=2d9513684874, createdName=thinkibmz_44722598, createdTime=Fri May 20 02:17:00 CST 2016, time=2016-05-20, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1555610, encodeId=3b941555610ed, content=<a href='/topic/show?id=dcd89053994' target=_blank style='color:#2F92EE;'>#西药#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=58, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=90539, encryptionId=dcd89053994, topicName=西药)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=4b4014636852, createdName=minzju5057, createdTime=Fri May 20 02:17:00 CST 2016, time=2016-05-20, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=86548, encodeId=72a286548b5, content=的确这样, beContent=null, objectType=article, channel=null, level=null, likeNumber=144, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=7cde98330, createdName=milkshark, createdTime=Thu May 19 07:39:00 CST 2016, time=2016-05-19, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=86546, encodeId=ec9d865464e, content=值得学习, beContent=null, objectType=article, channel=null, level=null, likeNumber=144, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=7cde98330, createdName=milkshark, createdTime=Thu May 19 07:38:00 CST 2016, time=2016-05-19, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=86257, encodeId=a0328625e06, content=学习一下!, beContent=null, objectType=article, channel=null, level=null, likeNumber=136, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=93f31631454, createdName=1dd8c52fm63(暂无匿称), createdTime=Wed May 18 14:59:00 CST 2016, time=2016-05-18, status=1, ipAttribution=)]
    2016-08-29 ylzr123

    深度好文,值得学习,赞!

    0

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    2016-05-20 QQ76174b26

    这样的文章要多学

    0

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    2016-05-20 minzju5057
  5. [GetPortalCommentsPageByObjectIdResponse(id=106626, encodeId=854f106626f0, content=深度好文,值得学习,赞!, beContent=null, objectType=article, channel=null, level=null, likeNumber=93, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/NUyjXTCJjo7s7ZCKOmmbBTD6nE7gcd5OZpvyGEzkxBP3S275k5ZJVrsPkotZhBglRHM9rKvcj1OgkssqhcnoPw8zIaMZTF8c/0, createdBy=4c441942088, createdName=ylzr123, createdTime=Mon Aug 29 07:54:00 CST 2016, time=2016-08-29, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=86668, encodeId=cb9a86668c6, content=这样的文章要多学, beContent=null, objectType=article, channel=null, level=null, likeNumber=143, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=20751724934, createdName=QQ76174b26, createdTime=Fri May 20 09:38:00 CST 2016, time=2016-05-20, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1545078, encodeId=d77d15450e8a9, content=<a href='/topic/show?id=b7abe4635e0' target=_blank style='color:#2F92EE;'>#禁忌#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=67, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=74635, encryptionId=b7abe4635e0, topicName=禁忌)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=2d9513684874, createdName=thinkibmz_44722598, createdTime=Fri May 20 02:17:00 CST 2016, time=2016-05-20, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1555610, encodeId=3b941555610ed, content=<a href='/topic/show?id=dcd89053994' target=_blank style='color:#2F92EE;'>#西药#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=58, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=90539, encryptionId=dcd89053994, topicName=西药)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=4b4014636852, createdName=minzju5057, createdTime=Fri May 20 02:17:00 CST 2016, time=2016-05-20, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=86548, encodeId=72a286548b5, content=的确这样, beContent=null, objectType=article, channel=null, level=null, likeNumber=144, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=7cde98330, createdName=milkshark, createdTime=Thu May 19 07:39:00 CST 2016, time=2016-05-19, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=86546, encodeId=ec9d865464e, content=值得学习, beContent=null, objectType=article, channel=null, level=null, likeNumber=144, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=7cde98330, createdName=milkshark, createdTime=Thu May 19 07:38:00 CST 2016, time=2016-05-19, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=86257, encodeId=a0328625e06, content=学习一下!, beContent=null, objectType=article, channel=null, level=null, likeNumber=136, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=93f31631454, createdName=1dd8c52fm63(暂无匿称), createdTime=Wed May 18 14:59:00 CST 2016, time=2016-05-18, status=1, ipAttribution=)]
    2016-05-19 milkshark

    的确这样

    0

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    2016-05-19 milkshark

    值得学习

    0

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    2016-05-18 1dd8c52fm63(暂无匿称)

    学习一下!

    0

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