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Gastroenterology:瑞金医院袁耀宗发现高膳食纤维摄入可减少结直肠腺瘤发病风险

2013-11-26 小木lemon dxy

结直肠腺瘤是癌症的先兆,对人类健康有潜在的致命性危险。关于膳食纤维摄入量和结直肠腺瘤发病风险的关系,目前尚未达成一致结论。为探究膳食纤维摄入与结直肠腺瘤的关系,上海交通大学瑞金医院消化科袁耀宗等进行了一项研究,对二者之间的关系进行了更为综合的定量分析,其结果在线发表于2013年11月8日的Gastroenterology杂志上。研究发现丰富的膳食纤维摄入可以减少结直肠腺瘤的发病风险。【原文下载】

结直肠腺瘤是癌症的先兆,对人类健康有潜在的致命性危险。关于膳食纤维摄入量和结直肠腺瘤发病风险的关系,目前尚未达成一致结论。为探究膳食纤维摄入与结直肠腺瘤的关系,上海交通大学瑞金医院消化科袁耀宗等进行了一项研究,对二者之间的关系进行了更为综合的定量分析,其结果在线发表于2013年11月8日的Gastroenterology杂志上。研究发现丰富的膳食纤维摄入可以减少结直肠腺瘤的发病风险。【原文下载

研究主要采用Meta分析的方法,通过搜索MEDLINE和EMBASE两个数据库中相关的文献,纳入了20项关于膳食纤维摄入和结直肠腺瘤关系的研究,包含16项病例对照研究和4项队列研究,共有10948个研究对象。

该研究结果发现,与低膳食纤维摄入组相比,高膳食纤维摄入可以使结直肠腺瘤发病风险减少28%,每天每增加10克的膳食纤维摄入可使结直肠腺瘤发病风险降低9%。16项病例对照研究数据的亚组分析结果显示,总的膳食纤维摄入可以减少34%的结直肠腺瘤发病风险,但是这种效应在4项队列研究中并不显著,只可以降低8%的发病风险。对膳食纤维进行细化分析发现,水果和谷类中的纤维可以显著降低结直肠腺瘤的风险,而蔬菜中纤维的作用并不明显。

该研究是第一次对膳食纤维摄入与结直肠腺瘤发病风险的关系进行综合深入的评估分析,其结果表明高膳食纤维摄入可以减少结直肠腺瘤的发病风险,尤其是水果和谷类中的纤维可以显著降低其风险。但是仍需设计严密而完善的前瞻性研究来继续探索验证这一点,更好地控制可能的混杂因素,为将来提出疾病预防干预措施提供更为信服的科学依据。

原文出处

Ben Q, Sun Y, Chai R, Qian A, Xu B, Yuan Y.Dietary Fiber Intake Reduces Risk for Colorectal Adenoma: a Meta-Analysis.Gastroenterology. 2013 Nov 8. 【原文下载

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    2014-07-25 许安
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    2013-11-28 zhaojie88
  6. [GetPortalCommentsPageByObjectIdResponse(id=1967271, encodeId=8176196e271a8, content=<a href='/topic/show?id=4d32102632d1' target=_blank style='color:#2F92EE;'>#高膳食纤维#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=66, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=102632, encryptionId=4d32102632d1, topicName=高膳食纤维)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=5ed3112, createdName=echonoir, createdTime=Wed Mar 26 08:53:00 CST 2014, time=2014-03-26, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=2063868, encodeId=febc20638688d, content=<a href='/topic/show?id=94ffe853a7' target=_blank style='color:#2F92EE;'>#Gastroenterol#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=52, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=7853, encryptionId=94ffe853a7, topicName=Gastroenterol)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=0bed488, createdName=jktdtl, createdTime=Tue Sep 23 21:53:00 CST 2014, time=2014-09-23, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1710682, encodeId=5ae31e1068228, content=<a href='/topic/show?id=9a1c289680' target=_blank style='color:#2F92EE;'>#AST#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=56, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=2896, encryptionId=9a1c289680, topicName=AST)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=8b9831894722, createdName=ms24272190615788285182, createdTime=Mon Jul 14 11:53:00 CST 2014, time=2014-07-14, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=2071512, encodeId=90a420e1512dd, content=<a href='/topic/show?id=9d4ee84647' target=_blank style='color:#2F92EE;'>#GAS#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=53, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=7846, encryptionId=9d4ee84647, topicName=GAS)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=e2dd327, createdName=许安, createdTime=Fri Jul 25 16:53:00 CST 2014, time=2014-07-25, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1350275, encodeId=f9b313502e5b0, content=<a href='/topic/show?id=224a85904ad' target=_blank style='color:#2F92EE;'>#膳食#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=59, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=85904, encryptionId=224a85904ad, topicName=膳食)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=4c37265, createdName=zhaojie88, createdTime=Thu Nov 28 05:53:00 CST 2013, time=2013-11-28, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1452656, encodeId=46ac14526568a, content=<a href='/topic/show?id=098ee8679ad' target=_blank style='color:#2F92EE;'>#结直肠#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=57, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=78679, encryptionId=098ee8679ad, topicName=结直肠)], attachment=null, authenticateStatus=null, createdAvatar=/v1.0.0/img/user_icon.png, createdBy=9ace5575596, createdName=crystal0564, createdTime=Thu Nov 28 05:53:00 CST 2013, time=2013-11-28, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1466269, encodeId=3ba01466269d7, content=<a href='/topic/show?id=afda85920c3' target=_blank style='color:#2F92EE;'>#膳食纤维摄入#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=62, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=85920, encryptionId=afda85920c3, topicName=膳食纤维摄入)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=dea96793953, createdName=linne322, createdTime=Thu Nov 28 05:53:00 CST 2013, time=2013-11-28, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1504172, encodeId=c6ef15041e2a9, content=<a href='/topic/show?id=7730e85412' target=_blank style='color:#2F92EE;'>#Gastroenterology#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=60, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=7854, encryptionId=7730e85412, topicName=Gastroenterology)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=21015, createdName=heli0118, createdTime=Thu Nov 28 05:53:00 CST 2013, time=2013-11-28, status=1, ipAttribution=)]
  7. [GetPortalCommentsPageByObjectIdResponse(id=1967271, encodeId=8176196e271a8, content=<a href='/topic/show?id=4d32102632d1' target=_blank style='color:#2F92EE;'>#高膳食纤维#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=66, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=102632, encryptionId=4d32102632d1, topicName=高膳食纤维)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=5ed3112, createdName=echonoir, createdTime=Wed Mar 26 08:53:00 CST 2014, time=2014-03-26, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=2063868, encodeId=febc20638688d, content=<a href='/topic/show?id=94ffe853a7' target=_blank style='color:#2F92EE;'>#Gastroenterol#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=52, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=7853, encryptionId=94ffe853a7, topicName=Gastroenterol)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=0bed488, createdName=jktdtl, createdTime=Tue Sep 23 21:53:00 CST 2014, time=2014-09-23, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1710682, encodeId=5ae31e1068228, content=<a href='/topic/show?id=9a1c289680' target=_blank style='color:#2F92EE;'>#AST#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=56, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=2896, encryptionId=9a1c289680, topicName=AST)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=8b9831894722, createdName=ms24272190615788285182, createdTime=Mon Jul 14 11:53:00 CST 2014, time=2014-07-14, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=2071512, encodeId=90a420e1512dd, content=<a href='/topic/show?id=9d4ee84647' target=_blank style='color:#2F92EE;'>#GAS#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=53, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=7846, encryptionId=9d4ee84647, topicName=GAS)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=e2dd327, createdName=许安, createdTime=Fri Jul 25 16:53:00 CST 2014, time=2014-07-25, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1350275, encodeId=f9b313502e5b0, content=<a href='/topic/show?id=224a85904ad' target=_blank style='color:#2F92EE;'>#膳食#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=59, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=85904, encryptionId=224a85904ad, topicName=膳食)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=4c37265, createdName=zhaojie88, createdTime=Thu Nov 28 05:53:00 CST 2013, time=2013-11-28, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1452656, encodeId=46ac14526568a, content=<a href='/topic/show?id=098ee8679ad' target=_blank style='color:#2F92EE;'>#结直肠#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=57, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=78679, encryptionId=098ee8679ad, topicName=结直肠)], attachment=null, authenticateStatus=null, createdAvatar=/v1.0.0/img/user_icon.png, createdBy=9ace5575596, createdName=crystal0564, createdTime=Thu Nov 28 05:53:00 CST 2013, time=2013-11-28, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1466269, encodeId=3ba01466269d7, content=<a href='/topic/show?id=afda85920c3' target=_blank style='color:#2F92EE;'>#膳食纤维摄入#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=62, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=85920, encryptionId=afda85920c3, topicName=膳食纤维摄入)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=dea96793953, createdName=linne322, createdTime=Thu Nov 28 05:53:00 CST 2013, time=2013-11-28, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1504172, encodeId=c6ef15041e2a9, content=<a href='/topic/show?id=7730e85412' target=_blank style='color:#2F92EE;'>#Gastroenterology#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=60, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=7854, encryptionId=7730e85412, topicName=Gastroenterology)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=21015, createdName=heli0118, createdTime=Thu Nov 28 05:53:00 CST 2013, time=2013-11-28, status=1, ipAttribution=)]
  8. [GetPortalCommentsPageByObjectIdResponse(id=1967271, encodeId=8176196e271a8, content=<a href='/topic/show?id=4d32102632d1' target=_blank style='color:#2F92EE;'>#高膳食纤维#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=66, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=102632, encryptionId=4d32102632d1, topicName=高膳食纤维)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=5ed3112, createdName=echonoir, createdTime=Wed Mar 26 08:53:00 CST 2014, time=2014-03-26, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=2063868, encodeId=febc20638688d, content=<a href='/topic/show?id=94ffe853a7' target=_blank style='color:#2F92EE;'>#Gastroenterol#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=52, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=7853, encryptionId=94ffe853a7, topicName=Gastroenterol)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=0bed488, createdName=jktdtl, createdTime=Tue Sep 23 21:53:00 CST 2014, time=2014-09-23, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1710682, encodeId=5ae31e1068228, content=<a href='/topic/show?id=9a1c289680' target=_blank style='color:#2F92EE;'>#AST#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=56, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=2896, encryptionId=9a1c289680, topicName=AST)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=8b9831894722, createdName=ms24272190615788285182, createdTime=Mon Jul 14 11:53:00 CST 2014, time=2014-07-14, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=2071512, encodeId=90a420e1512dd, content=<a href='/topic/show?id=9d4ee84647' target=_blank style='color:#2F92EE;'>#GAS#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=53, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=7846, encryptionId=9d4ee84647, topicName=GAS)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=e2dd327, createdName=许安, createdTime=Fri Jul 25 16:53:00 CST 2014, time=2014-07-25, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1350275, encodeId=f9b313502e5b0, content=<a href='/topic/show?id=224a85904ad' target=_blank style='color:#2F92EE;'>#膳食#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=59, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=85904, encryptionId=224a85904ad, topicName=膳食)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=4c37265, createdName=zhaojie88, createdTime=Thu Nov 28 05:53:00 CST 2013, time=2013-11-28, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1452656, encodeId=46ac14526568a, content=<a href='/topic/show?id=098ee8679ad' target=_blank style='color:#2F92EE;'>#结直肠#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=57, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=78679, encryptionId=098ee8679ad, topicName=结直肠)], attachment=null, authenticateStatus=null, createdAvatar=/v1.0.0/img/user_icon.png, createdBy=9ace5575596, createdName=crystal0564, createdTime=Thu Nov 28 05:53:00 CST 2013, time=2013-11-28, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1466269, encodeId=3ba01466269d7, content=<a href='/topic/show?id=afda85920c3' target=_blank style='color:#2F92EE;'>#膳食纤维摄入#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=62, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=85920, encryptionId=afda85920c3, topicName=膳食纤维摄入)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=dea96793953, createdName=linne322, createdTime=Thu Nov 28 05:53:00 CST 2013, time=2013-11-28, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1504172, encodeId=c6ef15041e2a9, content=<a href='/topic/show?id=7730e85412' target=_blank style='color:#2F92EE;'>#Gastroenterology#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=60, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=7854, encryptionId=7730e85412, topicName=Gastroenterology)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=21015, createdName=heli0118, createdTime=Thu Nov 28 05:53:00 CST 2013, time=2013-11-28, status=1, ipAttribution=)]
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