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EBUS-TBNA样品中的PD-L1检测结果是否可以指导ICI治疗？

2021-08-19 MedSci原创 MedSci原创

EBUS-TBNA
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EBUS-TBNA样品中的PD-L1检测结果是否可以指导ICI治疗-C-TBNA和EBUS-TBNA的应用-问题2

《梅斯直播课——支气管镜基本诊疗术及其临床应用》

回答问题2：EBUS-TBNA样品中的PD-L1检测结果是否可以指导ICI治疗？

 

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  1. [GetPortalCommentsPageByObjectIdResponse(id=1930275, encodeId=590019302e55d, content=<a href='/topic/show?id=0aac64623a' target=_blank style='color:#2F92EE;'>#EBUS-TBNA#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=68, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=6462, encryptionId=0aac64623a, topicName=EBUS-TBNA)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=63a4277, createdName=cy0324, createdTime=Fri Jan 21 21:52:53 CST 2022, time=2022-01-21, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=2083716, encodeId=ebc12083e16e3, content=<a href='/topic/show?id=685862555f0' target=_blank style='color:#2F92EE;'>#检测结果#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=63, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=62555, encryptionId=685862555f0, topicName=检测结果)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=4dfa37, createdName=huhuaidong387, createdTime=Thu Jan 13 01:52:53 CST 2022, time=2022-01-13, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1255114, encodeId=58821255114dd, content=<a href='/topic/show?id=be71139214f' target=_blank style='color:#2F92EE;'>#PD-L1#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=88, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=13921, encryptionId=be71139214f, topicName=PD-L1)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=e76f39, createdName=smartjoy, createdTime=Sat Aug 21 06:52:53 CST 2021, time=2021-08-21, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1009489, encodeId=e4281009489d5, content=学习了, beContent=null, objectType=article, channel=null, level=null, likeNumber=98, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://img.medsci.cn/20201109/6ea5abada2334aabb2737efec80d0f14/16a8a75d63a842369f74b14d4c0fcf86.jpg, createdBy=a8555433340, createdName=春江水暖, createdTime=Thu Aug 19 16:23:13 CST 2021, time=2021-08-19, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1009484, encodeId=c1bf1009484ad, content=学习了, beContent=null, objectType=article, channel=null, level=null, likeNumber=87, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=75035089920, createdName=145cf07em96暂无昵称, createdTime=Thu Aug 19 16:16:34 CST 2021, time=2021-08-19, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1009482, encodeId=c50e10094829f, content=学习了, beContent=null, objectType=article, channel=null, level=null, likeNumber=78, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=32b35555123, createdName=ms6000000538719126, createdTime=Thu Aug 19 15:57:38 CST 2021, time=2021-08-19, status=1, ipAttribution=)]
    2022-01-21 cy0324

    #EBUS-TBNA#

    0

  2. [GetPortalCommentsPageByObjectIdResponse(id=1930275, encodeId=590019302e55d, content=<a href='/topic/show?id=0aac64623a' target=_blank style='color:#2F92EE;'>#EBUS-TBNA#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=68, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=6462, encryptionId=0aac64623a, topicName=EBUS-TBNA)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=63a4277, createdName=cy0324, createdTime=Fri Jan 21 21:52:53 CST 2022, time=2022-01-21, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=2083716, encodeId=ebc12083e16e3, content=<a href='/topic/show?id=685862555f0' target=_blank style='color:#2F92EE;'>#检测结果#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=63, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=62555, encryptionId=685862555f0, topicName=检测结果)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=4dfa37, createdName=huhuaidong387, createdTime=Thu Jan 13 01:52:53 CST 2022, time=2022-01-13, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1255114, encodeId=58821255114dd, content=<a href='/topic/show?id=be71139214f' target=_blank style='color:#2F92EE;'>#PD-L1#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=88, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=13921, encryptionId=be71139214f, topicName=PD-L1)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=e76f39, createdName=smartjoy, createdTime=Sat Aug 21 06:52:53 CST 2021, time=2021-08-21, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1009489, encodeId=e4281009489d5, content=学习了, beContent=null, objectType=article, channel=null, level=null, likeNumber=98, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://img.medsci.cn/20201109/6ea5abada2334aabb2737efec80d0f14/16a8a75d63a842369f74b14d4c0fcf86.jpg, createdBy=a8555433340, createdName=春江水暖, createdTime=Thu Aug 19 16:23:13 CST 2021, time=2021-08-19, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1009484, encodeId=c1bf1009484ad, content=学习了, beContent=null, objectType=article, channel=null, level=null, likeNumber=87, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=75035089920, createdName=145cf07em96暂无昵称, createdTime=Thu Aug 19 16:16:34 CST 2021, time=2021-08-19, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1009482, encodeId=c50e10094829f, content=学习了, beContent=null, objectType=article, channel=null, level=null, likeNumber=78, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=32b35555123, createdName=ms6000000538719126, createdTime=Thu Aug 19 15:57:38 CST 2021, time=2021-08-19, status=1, ipAttribution=)]
    2022-01-13 huhuaidong387

    #检测结果#

    0

  3. [GetPortalCommentsPageByObjectIdResponse(id=1930275, encodeId=590019302e55d, content=<a href='/topic/show?id=0aac64623a' target=_blank style='color:#2F92EE;'>#EBUS-TBNA#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=68, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=6462, encryptionId=0aac64623a, topicName=EBUS-TBNA)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=63a4277, createdName=cy0324, createdTime=Fri Jan 21 21:52:53 CST 2022, time=2022-01-21, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=2083716, encodeId=ebc12083e16e3, content=<a href='/topic/show?id=685862555f0' target=_blank style='color:#2F92EE;'>#检测结果#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=63, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=62555, encryptionId=685862555f0, topicName=检测结果)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=4dfa37, createdName=huhuaidong387, createdTime=Thu Jan 13 01:52:53 CST 2022, time=2022-01-13, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1255114, encodeId=58821255114dd, content=<a href='/topic/show?id=be71139214f' target=_blank style='color:#2F92EE;'>#PD-L1#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=88, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=13921, encryptionId=be71139214f, topicName=PD-L1)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=e76f39, createdName=smartjoy, createdTime=Sat Aug 21 06:52:53 CST 2021, time=2021-08-21, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1009489, encodeId=e4281009489d5, content=学习了, beContent=null, objectType=article, channel=null, level=null, likeNumber=98, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://img.medsci.cn/20201109/6ea5abada2334aabb2737efec80d0f14/16a8a75d63a842369f74b14d4c0fcf86.jpg, createdBy=a8555433340, createdName=春江水暖, createdTime=Thu Aug 19 16:23:13 CST 2021, time=2021-08-19, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1009484, encodeId=c1bf1009484ad, content=学习了, beContent=null, objectType=article, channel=null, level=null, likeNumber=87, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=75035089920, createdName=145cf07em96暂无昵称, createdTime=Thu Aug 19 16:16:34 CST 2021, time=2021-08-19, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1009482, encodeId=c50e10094829f, content=学习了, beContent=null, objectType=article, channel=null, level=null, likeNumber=78, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=32b35555123, createdName=ms6000000538719126, createdTime=Thu Aug 19 15:57:38 CST 2021, time=2021-08-19, status=1, ipAttribution=)]
    2021-08-21 smartjoy

    #PD-L1#

    0

  4. [GetPortalCommentsPageByObjectIdResponse(id=1930275, encodeId=590019302e55d, content=<a href='/topic/show?id=0aac64623a' target=_blank style='color:#2F92EE;'>#EBUS-TBNA#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=68, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=6462, encryptionId=0aac64623a, topicName=EBUS-TBNA)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=63a4277, createdName=cy0324, createdTime=Fri Jan 21 21:52:53 CST 2022, time=2022-01-21, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=2083716, encodeId=ebc12083e16e3, content=<a href='/topic/show?id=685862555f0' target=_blank style='color:#2F92EE;'>#检测结果#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=63, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=62555, encryptionId=685862555f0, topicName=检测结果)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=4dfa37, createdName=huhuaidong387, createdTime=Thu Jan 13 01:52:53 CST 2022, time=2022-01-13, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1255114, encodeId=58821255114dd, content=<a href='/topic/show?id=be71139214f' target=_blank style='color:#2F92EE;'>#PD-L1#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=88, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=13921, encryptionId=be71139214f, topicName=PD-L1)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=e76f39, createdName=smartjoy, createdTime=Sat Aug 21 06:52:53 CST 2021, time=2021-08-21, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1009489, encodeId=e4281009489d5, content=学习了, beContent=null, objectType=article, channel=null, level=null, likeNumber=98, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://img.medsci.cn/20201109/6ea5abada2334aabb2737efec80d0f14/16a8a75d63a842369f74b14d4c0fcf86.jpg, createdBy=a8555433340, createdName=春江水暖, createdTime=Thu Aug 19 16:23:13 CST 2021, time=2021-08-19, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1009484, encodeId=c1bf1009484ad, content=学习了, beContent=null, objectType=article, channel=null, level=null, likeNumber=87, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=75035089920, createdName=145cf07em96暂无昵称, createdTime=Thu Aug 19 16:16:34 CST 2021, time=2021-08-19, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1009482, encodeId=c50e10094829f, content=学习了, beContent=null, objectType=article, channel=null, level=null, likeNumber=78, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=32b35555123, createdName=ms6000000538719126, createdTime=Thu Aug 19 15:57:38 CST 2021, time=2021-08-19, status=1, ipAttribution=)]
    2021-08-19 春江水暖

    学习了

    0

  5. [GetPortalCommentsPageByObjectIdResponse(id=1930275, encodeId=590019302e55d, content=<a href='/topic/show?id=0aac64623a' target=_blank style='color:#2F92EE;'>#EBUS-TBNA#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=68, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=6462, encryptionId=0aac64623a, topicName=EBUS-TBNA)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=63a4277, createdName=cy0324, createdTime=Fri Jan 21 21:52:53 CST 2022, time=2022-01-21, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=2083716, encodeId=ebc12083e16e3, content=<a href='/topic/show?id=685862555f0' target=_blank style='color:#2F92EE;'>#检测结果#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=63, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=62555, encryptionId=685862555f0, topicName=检测结果)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=4dfa37, createdName=huhuaidong387, createdTime=Thu Jan 13 01:52:53 CST 2022, time=2022-01-13, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1255114, encodeId=58821255114dd, content=<a href='/topic/show?id=be71139214f' target=_blank style='color:#2F92EE;'>#PD-L1#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=88, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=13921, encryptionId=be71139214f, topicName=PD-L1)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=e76f39, createdName=smartjoy, createdTime=Sat Aug 21 06:52:53 CST 2021, time=2021-08-21, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1009489, encodeId=e4281009489d5, content=学习了, beContent=null, objectType=article, channel=null, level=null, likeNumber=98, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://img.medsci.cn/20201109/6ea5abada2334aabb2737efec80d0f14/16a8a75d63a842369f74b14d4c0fcf86.jpg, createdBy=a8555433340, createdName=春江水暖, createdTime=Thu Aug 19 16:23:13 CST 2021, time=2021-08-19, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1009484, encodeId=c1bf1009484ad, content=学习了, beContent=null, objectType=article, channel=null, level=null, likeNumber=87, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=75035089920, createdName=145cf07em96暂无昵称, createdTime=Thu Aug 19 16:16:34 CST 2021, time=2021-08-19, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1009482, encodeId=c50e10094829f, content=学习了, beContent=null, objectType=article, channel=null, level=null, likeNumber=78, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=32b35555123, createdName=ms6000000538719126, createdTime=Thu Aug 19 15:57:38 CST 2021, time=2021-08-19, status=1, ipAttribution=)]
    2021-08-19 145cf07em96暂无昵称

    学习了

    0

  6. [GetPortalCommentsPageByObjectIdResponse(id=1930275, encodeId=590019302e55d, content=<a href='/topic/show?id=0aac64623a' target=_blank style='color:#2F92EE;'>#EBUS-TBNA#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=68, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=6462, encryptionId=0aac64623a, topicName=EBUS-TBNA)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=63a4277, createdName=cy0324, createdTime=Fri Jan 21 21:52:53 CST 2022, time=2022-01-21, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=2083716, encodeId=ebc12083e16e3, content=<a href='/topic/show?id=685862555f0' target=_blank style='color:#2F92EE;'>#检测结果#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=63, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=62555, encryptionId=685862555f0, topicName=检测结果)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=4dfa37, createdName=huhuaidong387, createdTime=Thu Jan 13 01:52:53 CST 2022, time=2022-01-13, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1255114, encodeId=58821255114dd, content=<a href='/topic/show?id=be71139214f' target=_blank style='color:#2F92EE;'>#PD-L1#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=88, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=13921, encryptionId=be71139214f, topicName=PD-L1)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=e76f39, createdName=smartjoy, createdTime=Sat Aug 21 06:52:53 CST 2021, time=2021-08-21, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1009489, encodeId=e4281009489d5, content=学习了, beContent=null, objectType=article, channel=null, level=null, likeNumber=98, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://img.medsci.cn/20201109/6ea5abada2334aabb2737efec80d0f14/16a8a75d63a842369f74b14d4c0fcf86.jpg, createdBy=a8555433340, createdName=春江水暖, createdTime=Thu Aug 19 16:23:13 CST 2021, time=2021-08-19, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1009484, encodeId=c1bf1009484ad, content=学习了, beContent=null, objectType=article, channel=null, level=null, likeNumber=87, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=75035089920, createdName=145cf07em96暂无昵称, createdTime=Thu Aug 19 16:16:34 CST 2021, time=2021-08-19, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1009482, encodeId=c50e10094829f, content=学习了, beContent=null, objectType=article, channel=null, level=null, likeNumber=78, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=32b35555123, createdName=ms6000000538719126, createdTime=Thu Aug 19 15:57:38 CST 2021, time=2021-08-19, status=1, ipAttribution=)]
    2021-08-19 ms6000000538719126

    学习了

    0

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J Thor Oncol：超声引导针吸活检术能安全有效地诊断老年肺癌

近日，来自曼彻斯特大学的研究人员通过研究发现，对肺癌患者进行组织取样诊断检测或许仅在老年患者个体中是安全的，这就呼吁医生们需要开发一种更为准确安全的诊断技术，来保证患者的安全，当然这为医生们选择合适的疗法治疗肺癌患者也具有一定的价值，相关研究刊登于国际杂志Journal of Thoracic Oncology上。肺癌患者中有一半患者都是在70多岁时被诊断出了癌症，但是有研究却表明这些老年患者并不

PD-L1测试在使用内核超声引导针吸入（EBUS-TBNA）中获得的大部分标本中是否可行？

PD-L1测试在使用内核超声引导针吸入（EBUS-TBNA）中获得的大部分标本中是否可行-C-TBNA和EBUS-TBNA的应用_问题1.

Ann Thorac Surg：上海胸科医院韩宝惠等发现EBUS-TBNA对可疑胸内结核有很高诊断价值

支气管内超声引导下经支气管针吸活检（EBUS-TBNA）是一种微创操作，其对纵隔及肺门淋巴结的诊断评估具有很高的敏感性，但它在诊断胸内结核病（TB）方面的作用尚未明确。为此，来自上海交通大学附属上海市胸科医院内镜中心和肺内科的韩宝惠及其同事进行了一项研究，研究结果发表于2013年9月12日出版的《胸外科年鉴》（Ann Thorac Surg）杂志上。研究结果显示：EBUS-TBNA对于可疑的胸内结

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