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DCR: 直肠癌完全直肠系膜切除手术后三种皮瓣重建技术短期疗效的比较

2020-04-19 MedSci原创 MedSci原创

晚期或复发性盆腔恶性肿瘤的手术会导致会阴部缺损,难以愈合。肌皮瓣可填补缺损并加速愈合。本研究旨在比较完全直肠系膜切除手术后的3种皮瓣手术方法的治疗效果。

背景:晚期或复发性盆腔恶性肿瘤的手术会导致会阴部缺损,难以愈合。肌皮瓣可填补缺损并加速愈合。本研究旨在比较完全直肠系膜切除手术后的3种皮瓣手术方法的治疗效果。

方法:本项研究是一项对前瞻性数据库的回顾性分析。研究人员对在2007年至2016年间进行了全部直肠系膜切除手术后需要进行皮瓣重建患者进行了回顾性分析。主要观察指标:评估了腹直肌斜肌皮瓣与垂直腹直肌皮瓣以及臀下动脉穿孔皮瓣重建后的预后效果。

结果:本项研究中有65例(59%)腹直肌斜肌皮瓣移植,30例(27.3%)腹直肌直肌皮瓣移植和15例(13.7%)臀下动脉穿支肌皮瓣移植。这些患者中分别有12例(18.5%),10例(33.3%)和8例(53.3%)的患者中进行了切除术(p = 0.016)。60例(92.3%),26例(86.7%)和11例(73.3%)的患者接受了术前放疗(p = 0.11)。皮瓣感染和裂开发生在7(10.8%),1(3.3%)和4(26.7%)患者中。与垂直腹直肌皮瓣相比,下臀动脉穿支皮瓣发生皮瓣并发症的风险增加(p = 0.036)。臀下动脉穿孔皮瓣(OR,6.26; p = 0.02)和肥胖症(OR,4.96; p= 0.02)与皮瓣并发症相关。随着时间的推移,仅腹直肌斜肌皮瓣的并发症显着减少(p = 0.03)。

结论:三种皮肌瓣移植技术并无明显优劣之分,均应该按照人群特点进行个体化选择。

原始出处:

Baird, Daniel. Et al. A Comparison of the Short-term Outcomes of Three Flap Reconstruction Techniques Used After Beyond Total Mesorectal Excision Surgery for Anorectal Cancer. Diseases of the Colon & Rectum.2020.

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    2020-04-21 sunylz
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    2020-04-21 zzc2216
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    2020-04-19 内科新手

    谢谢梅斯提供这么好的信息,学到很多

    0

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