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farletuzumab治疗卵巢癌将开始III期临床研究

2012-04-16 cyy123 cyy123

Eisai的分公司Morphotek,完成了FAR-131研究(III期)的志愿者招募工作,用于治疗第一次复发铂敏感卵巢癌患者。 III期farletuzumab研究将设置:随机、双盲、安慰剂控制等的对照。 研究将评估两种不同剂量的farletuzumab结合标准治疗同只采用标准治疗的疗效,通过无进展存活率的改善来比较。 初级终末点和次级终末点将研究:提高整体存活率,客观肿瘤应答及患者第二次

Eisai的分公司Morphotek,完成了FAR-131研究(III期)的志愿者招募工作,用于治疗第一次复发铂敏感卵巢癌患者。

III期farletuzumab研究将设置:随机、双盲、安慰剂控制等的对照。

研究将评估两种不同剂量的farletuzumab结合标准治疗同只采用标准治疗的疗效,通过无进展存活率的改善来比较。

初级终末点和次级终末点将研究:提高整体存活率,客观肿瘤应答及患者第二次缓解期长度。

farletuzumab是一种靶向定位叶酸受体α的人源化单克隆抗体,主要在非粘液上皮细胞卵巢癌内表达。(生物谷 bioon.com)

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FDA批准审查了Eisai公司DACOGEN药物的补充新药申请

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    2012-11-10 snf701207
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    2012-07-03 juliusluan78
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