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Diabetic Med:增加膳食中的蛋白质量对1型糖尿病个体的餐后葡萄糖水平产生剂量依赖性影响

2017-06-28 MedSci MedSci原创

近日,国际杂志 《Diabetic medicine》上在线发表一项增加膳食中的蛋白质量对1型糖尿病个体的餐后葡萄糖水平产生剂量依赖性影响的研究。 对1型糖尿病参与者[年龄10-40岁,糖化血红蛋白1C ≤64mmol/mol(8%),BMI≤第91百分位数](可忽略的脂肪)以随机顺序进行超过5天的30克碳水化合物饮用测试。并加入0(对照),12.5,25,50和75g的蛋白质(乳清分离物0g

近日,国际杂志 《Diabetic medicine》上在线发表一项增加膳食中的蛋白质量对1糖尿病个体的餐后葡萄糖水平产生剂量依赖性影响的研究。

1糖尿病参与者[年龄10-40岁,糖化血红蛋白1C 64mmol/mol8%),BMI≤第91百分位数](可忽略的脂肪)以随机顺序进行超过5天的30克碳水化合物饮用测试。并加入0(对照),12.5,25,5075g的蛋白质(乳清分离物0g / kg碳水化合物,0g / kg脂质)。对碳水化合物的参与者注射标准剂量的胰岛素,通过连续5 h的葡萄糖监测评估餐后血糖。

最后,对来自27位参与者(15名男性)的数据进行分析。随着蛋白质含量的增加出现了剂量效应关系。在3060分钟时间点观察到蛋白质剂量和平均偏移之间显著负相关(P = 0.007P = 0.002)。在90分钟和120分钟的时间点没有显示显著的关系。此后,剂量 - 反应关系发生逆转,每个150-300分钟时间点之间存在显著正相关关系(P <0.004)。加入蛋白质试验饮料的受试者平均血糖水平从150300分钟(P <0.005)显著升高,与对照试验相比(P < 0.001),加入75 g蛋白质血糖浓度平均有 5 mmol/l 升高。

在含有一致的碳水化合物低脂肪膳食中增加蛋白质含量能够在餐后早期(0-60分钟)内减少葡萄糖剧增,随后剂量依赖性地增加血糖浓度。

原始出处:

M. A. Paterson, C. E. M. Smart, P. E. Lopez, et al. Increasing the protein quantity in a meal results in dose-dependent effects on postprandial glucose levels in individuals with Type 1 diabetes mellitus

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  5. 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status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=216450, encodeId=a9ef21645006, content=学习了,涨知识, beContent=null, objectType=article, channel=null, level=null, likeNumber=78, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://img.medsci.cn/20220115/46bcf39c32de4aa6b45c5f9d66c8ee77/6cb4a20c55bb4b7691122f47747bfca2.jpg, createdBy=9dad1662329, createdName=1ddf0692m34(暂无匿称), createdTime=Wed Jun 28 22:30:21 CST 2017, time=2017-06-28, status=1, ipAttribution=)]
  6. 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encodeId=cdc221690687, content=学习了谢谢分享!!, beContent=null, objectType=article, channel=null, level=null, likeNumber=66, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://img.medsci.cn/20200816/e4675a86ea694f12b82202b320dc2654/12f6b900498349e994ce8f516a584d6a.jpg, createdBy=09431951290, createdName=大爰, createdTime=Fri Jun 30 05:18:20 CST 2017, time=2017-06-30, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=216557, encodeId=d63121655e33, content=好文,值得点赞,更值得收藏!慢慢领会学习的。给点个赞!, beContent=null, objectType=article, channel=null, level=null, likeNumber=60, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/NUyjXTCJjo7s7ZCKOmmbBTD6nE7gcd5OZpvyGEzkxBP3S275k5ZJVrsPkotZhBglRHM9rKvcj1OgkssqhcnoPw8zIaMZTF8c/0, createdBy=4c441942088, createdName=ylzr123, createdTime=Thu Jun 29 07:16:16 CST 2017, time=2017-06-29, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=216450, encodeId=a9ef21645006, content=学习了,涨知识, beContent=null, objectType=article, channel=null, level=null, likeNumber=78, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://img.medsci.cn/20220115/46bcf39c32de4aa6b45c5f9d66c8ee77/6cb4a20c55bb4b7691122f47747bfca2.jpg, createdBy=9dad1662329, createdName=1ddf0692m34(暂无匿称), createdTime=Wed Jun 28 22:30:21 CST 2017, time=2017-06-28, status=1, ipAttribution=)]
    2017-06-30 zhaojie88
  7. 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status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=216450, encodeId=a9ef21645006, content=学习了,涨知识, beContent=null, objectType=article, channel=null, level=null, likeNumber=78, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://img.medsci.cn/20220115/46bcf39c32de4aa6b45c5f9d66c8ee77/6cb4a20c55bb4b7691122f47747bfca2.jpg, createdBy=9dad1662329, createdName=1ddf0692m34(暂无匿称), createdTime=Wed Jun 28 22:30:21 CST 2017, time=2017-06-28, status=1, ipAttribution=)]
  8. [GetPortalCommentsPageByObjectIdResponse(id=1760071, encodeId=d40f1e60071c9, content=<a href='/topic/show?id=9bea33520d' target=_blank style='color:#2F92EE;'>#BET#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=64, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=3352, encryptionId=9bea33520d, topicName=BET)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=9a1a37427546, createdName=ms5439512287675881, createdTime=Sun Dec 31 19:32:00 CST 2017, time=2017-12-31, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1637874, encodeId=102e163e8740b, content=<a href='/topic/show?id=afda591646' target=_blank style='color:#2F92EE;'>#DIA#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=62, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=5916, encryptionId=afda591646, topicName=DIA)], attachment=null, authenticateStatus=null, createdAvatar=null, 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status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=216450, encodeId=a9ef21645006, content=学习了,涨知识, beContent=null, objectType=article, channel=null, level=null, likeNumber=78, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://img.medsci.cn/20220115/46bcf39c32de4aa6b45c5f9d66c8ee77/6cb4a20c55bb4b7691122f47747bfca2.jpg, createdBy=9dad1662329, createdName=1ddf0692m34(暂无匿称), createdTime=Wed Jun 28 22:30:21 CST 2017, time=2017-06-28, status=1, ipAttribution=)]
    2017-06-30 大爰

    学习了谢谢分享!!

    0

  9. 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status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=216450, encodeId=a9ef21645006, content=学习了,涨知识, beContent=null, objectType=article, channel=null, level=null, likeNumber=78, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://img.medsci.cn/20220115/46bcf39c32de4aa6b45c5f9d66c8ee77/6cb4a20c55bb4b7691122f47747bfca2.jpg, createdBy=9dad1662329, createdName=1ddf0692m34(暂无匿称), createdTime=Wed Jun 28 22:30:21 CST 2017, time=2017-06-28, status=1, ipAttribution=)]
    2017-06-29 ylzr123

    好文,值得点赞,更值得收藏!慢慢领会学习的。给点个赞!

    0

  10. 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status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=216450, encodeId=a9ef21645006, content=学习了,涨知识, beContent=null, objectType=article, channel=null, level=null, likeNumber=78, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://img.medsci.cn/20220115/46bcf39c32de4aa6b45c5f9d66c8ee77/6cb4a20c55bb4b7691122f47747bfca2.jpg, createdBy=9dad1662329, createdName=1ddf0692m34(暂无匿称), createdTime=Wed Jun 28 22:30:21 CST 2017, time=2017-06-28, status=1, ipAttribution=)]
    2017-06-28 1ddf0692m34(暂无匿称)

    学习了,涨知识

    0

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近日,国际杂志 《Diabetic medicine》上在线发表一项关于为Ⅰ型糖尿病儿童,青少年和家庭开发可接受和可行的自我管理小组的研究,这项研究开发了可接受和可行的自我管理干预措施,解决了Ⅰ型糖尿病儿童和青少年及其父母的的自我确认的需求。

Diabetic Med:影响伦敦南部Ⅰ型糖尿病结构化教育的因素

近日,国际杂志 《Diabetic medicine》上在线发表一项关于影响伦敦南部Ⅰ型糖尿病结构化教育的因素的研究,旨在调查影响当地人Ⅰ型糖尿病患者接受结构化教育的因素,以了解为什么接受程度较低。 根据是否参与正常饮食调整剂量(DAFNE),研究人员在伦敦南部两个行政区进行了Ⅰ型糖尿病成年人的横断面研究。使用单变量分析比较人口统计学,血糖控制和服务,并按种族进行亚组分析,采用探索回归模型识别影

Diabetic Med:葡萄糖耐量异常和Ⅱ型糖尿病患者的行走方式改变和不稳定性增加与小纤维神经病变有关?

近日,国际杂志 《Diabetic medicine》上在线发表一项关于调查葡萄糖耐量异常患者和Ⅱ型糖尿病患者的行走方式和动态摇摆(不稳定)的变化与神经病变和维生素D水平的严重程度的相关性研究。

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