JASN：透析患者补充维生素D不能改善贫血症状

2015-12-19 MedSci译 MedSci原创

根据即将出现在美国肾脏病杂志JASN的一项研究，补充维生素D不能改善血液透析患者的贫血状况。营养维生素D在体内，骨外具有许多功能，维生素D缺乏牵涉到很多疾病，从心血管疾病到癌症。初步证据表明，营养补充维生素D可以通过增加血细胞产生，红细胞生成对透析患者有益。由于许多肾功能不全的患者会发生贫血或红细胞水平较低，补充维生素D将对这些人有益。在这项最大规模的检测维生素D对透析患者的影响的随机临床试验中，

根据即将出现在美国肾脏病杂志JASN的一项研究，补充维生素D不能改善血液透析患者的贫血状况。

营养维生素D在体内，骨外具有许多功能，维生素D缺乏牵涉到很多疾病，从心血管疾病到癌症。初步证据表明，营养补充维生素D可以通过增加血细胞产生，红细胞生成对透析患者有益。由于许多肾功能不全的患者会发生贫血或红细胞水平较低，补充维生素D将对这些人有益。

在这项最大规模的检测维生素D对透析患者的影响的随机临床试验中，医学博士Dana Miskulin（塔夫茨医学中心）和她的同事发现维生素D2补充剂6个月并没有减少透析病人用药物刺激红细胞产生的需要。

“这项研究也没有发现血液透析患者补充营养维生素D对其他几个次级结果包括甲状旁腺激素水平，炎症标志物，感染，或心血管事件的影响，但这些临床结果的统计力量是有限的，”Miskulin博士说。该试验共包括了被随机分配到补充6个月的维生素D2或安慰剂治疗的276例患者。

原始出处：

D. C. Miskulin, K. Majchrzak, H. Tighiouart, R. S. Muther,Ergocalciferol Supplementation in Hemodialysis Patients With Vitamin D Deficiency,JASN,2015.12.18

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#插入话题

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2017-02-14 1ddf0692m34(暂无匿称)

VD还可以改善贫血

70 0
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2016-07-06 chenhongpeng

#ASN#

56 0
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2016-04-08 medscijoin

#贫血症#

62 0
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2015-12-26 hixiaoluo

值得看，好好收藏

120 0
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2015-12-21 ewsr6

#透析患者#

57 0
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2015-12-20 三三五五

更长远一点能不能影响？

97 0
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2015-12-20 a191008346

很喜欢这种研究

121 0
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2015-12-19 chenhui888

why？

106 0

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JASN：透析患者补充维生素D不能改善贫血症状

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