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Semin Arthritis Rheu:2型糖尿病会增加肌肉骨骼疼痛的风险吗?

2020-06-23 xiangting MedSci原创

2型糖尿病患者更有可能报告肩/颈、膝关节或髋部的肌肉骨骼疼痛。此外,2型糖尿病患者,尤其是女性,更容易出现颈/肩痛。

这项研究探讨了横断面的相关性以及调整重要合并症后,2型糖尿病是否会增加肌肉骨骼疼痛的风险。

该研究使用来自英国生物银行参与者的数据:横断面分析(2006-2010年)495,327例,纵向分析(2014-2016)16,875例。2型糖尿病是自我报告的,并随后在问诊中进行证实。如果参与者报告有影响日常活动的背部、膝关节、髋关节或颈/肩疼痛,则被诊断为肌肉骨骼疼痛,不到1个月为近期疼痛,超过3个月为慢性疼痛。

在横断面调整的logistic回归分析中,2型糖尿病与近期和慢性颈/肩疼痛[OR 1.14,95%CI 1.10-1.18;OR 1.15,95%CI 1.10-1.19]、髋部疼痛[OR 1.13,95%CI 1.08-1.17;OR 1.14,95%CI 1.09-1.19]以及慢性膝关节疼痛[OR 1.01,95%CI 1.01-1.01]相关。在纵向调整分析中,2型糖尿病增加了近期和慢性颈/肩疼痛的风险[OR 1.39,95%CI 1.01-1.91;OR 1.56;95%CI 1.14-2.19]。

2型糖尿病患者更有可能报告肩/颈、膝关节或髋部的肌肉骨骼疼痛。此外,2型糖尿病患者,尤其是女性,更容易出现颈/肩痛。这项研究强调了在糖尿病患者中应考虑进行骨骼肌肉筛查,并促使研究骨骼肌肉疼痛与2型糖尿病之间关联的机制,从而预防或改善治疗。

原始出处:

Ana Paula Carvalho-e-Silva. Does type 2 diabetes increase the risk of musculoskeletal pain? Cross-sectional and longitudinal analyses of UK biobank data. Semin Arthritis Rheu. August 2020.

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    2020-06-25 zhaojie88
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    2020-06-23 misszhang

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