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NEJM:急性会厌炎,可大可小!

2015-04-13 陈说 译 MedSci原创

近日,一位65岁的女患者来到医院急诊室就诊,声称自己的喉咙部出现疼痛已经有1周了,现在更是感到吞咽困难、声音沙哑和自我感觉有发热的状况。在基本的生命体征监测中,发现她的体温、血压和血氧饱和度都是正常的(血压:140/86mmHg,血氧饱和度98%)。 通过体格检查发现,该女患者的会厌部有轻度压痛感,和颈部前方有肿胀的现象,但无颈淋巴结肿大或张口流涎现象。颈外侧软组织的X线影像



近日,一位65岁的女患者来到医院急诊室就诊,声称自己的喉咙部出现疼痛已经有1周了,现在更是感到吞咽困难、声音沙哑和自我感觉有发热的状况。在基本的生命体征监测中,发现她的体温、血压和血氧饱和度都是正常的(血压:140/86mmHg,血氧饱和度98%)。

通过体格检查发现,该女患者的会厌部有轻度压痛感,和颈部前方有肿胀的现象,但无颈淋巴结肿大或张口流涎现象。颈外侧软组织的X线影像显示会厌部“拇指征”(图A,箭头所指处),表明会厌出现肿胀,怀疑为会厌炎。而颈部的计算机断层扫描(CT)显示会厌部(图B,箭头所指处)、舌底部及舌扁桃体均出现了严重的肿胀和水肿。在间接喉镜检查下,可以看到会厌和舌根部位存在有红斑和炎症现象。这对于临床上鉴别诊断舌扁桃体肿大有重要的临床意义。

由于该患者存在气道狭窄可能发展为窒息的风险,主治医生立即按照会厌炎的常规治疗,使用头孢曲松钠和地塞米松对其进行处理以尽快控制炎症的发展。此外,还对该女患者作留院密切观察48小时处理。

经过3天的治疗后,该患者的血培养结果显示阴性。会厌部水肿症状明显有所好转,现今已经能够经口进食了。最后,该患者决定出院回家继续口服1个星期的头孢呋辛抗生素来完成整个治疗。

医学知识:

急性会厌炎:

急性会厌炎又称声门上喉炎或会厌前咽峡炎,是一种特殊的、主要累及喉部声门上区的会厌及其周围组织(包括会厌谷、杓会厌襞等)的急性炎症病变,以会厌高度水肿为主要特征。急性会厌炎是喉科的急重症之一,儿童及成人皆可出现,主要表现为全身中毒症状、吞咽及呼吸困难。急性会厌炎病情进展迅速,多数患者经及时治疗可获得痊愈,少数病情凶险,很快窒息,死亡率较高。

治疗要点:一旦确诊,需住院治疗。尽快控制感染,静脉注射足量的抗生素和糖皮质激素,如头孢类抗生素、地塞米松等。急性变态反应性会厌炎患者首先进行变态反应治疗。如喉阻塞程度较严重则按喉阻塞的处理原则治疗。如会厌舌面脓肿形成,或脓肿虽已破裂仍引流不畅时,应行切开排脓。

原始出处:

Venkata Angirekula,and Ashrit Multani.Epiglottitis in an Adult.N Engl J Med 2015; 372:e20April 9, 2015DOI: 10.1056/NEJMicm1400061



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    2016-09-30 double19999

    处理起来,蛮困难

    0

  2. [GetPortalCommentsPageByObjectIdResponse(id=137922, encodeId=863613e92226, content=处理起来,蛮困难, beContent=null, objectType=article, channel=null, level=null, likeNumber=87, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/NUyjXTCJjo6KcicAVC1MwuHuBzGfFa0ZqPJYqr8iciaolWKTYMBxib5icxqsU2OEBYjj5ticwp82e8Zwx1luhoXzErojvkibyVwMF6O/0, createdBy=daf91941768, createdName=double19999, createdTime=Fri Sep 30 12:04:09 CST 2016, time=2016-09-30, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=96587, encodeId=3ca29658e26, content=积极检查治疗,防止喉阻塞。, beContent=null, objectType=article, channel=null, level=null, likeNumber=98, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://cdnapi.center.medsci.cn/medsci/head/2017/04/21/72142930668371951a41ef4ea4b233e6.jpg, createdBy=dcbc1715228, createdName=刘煜, createdTime=Sun Aug 07 06:06:00 CST 2016, time=2016-08-07, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1664853, encodeId=1977166485354, content=<a href='/topic/show?id=13792580544' target=_blank style='color:#2F92EE;'>#会厌炎#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=0, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=25805, encryptionId=13792580544, topicName=会厌炎)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=1dfe25855341, createdName=ms1692810954239974, createdTime=Fri Mar 18 13:35:00 CST 2016, time=2016-03-18, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=25447, encodeId=ff682544ec4, content=儿童的更凶险,要密切关注, beContent=null, objectType=article, channel=null, level=null, likeNumber=133, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=934b1626634, createdName=Medxie, createdTime=Sun May 31 07:04:00 CST 2015, time=2015-05-31, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=21557, encodeId=187a2155e9c, content=碰但了一列,但是还要小心,处理不好很容易出问题!, beContent=null, objectType=article, channel=null, level=null, likeNumber=167, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/ajNVdqHZLLCEEr4dM45RatXXGAkFCicnNYiasFiaRicicO1YWsIeTFOhgapauqib8Z8TChNB3ttVC5RqNHptDvAxA72Q/0, createdBy=a82a1611288, createdName=yydlt, createdTime=Tue Apr 21 13:50:00 CST 2015, time=2015-04-21, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=21556, encodeId=a9ab21556f2, content=即使气管切开吧!, beContent=null, objectType=article, channel=null, level=null, likeNumber=119, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/ajNVdqHZLLCEEr4dM45RatXXGAkFCicnNYiasFiaRicicO1YWsIeTFOhgapauqib8Z8TChNB3ttVC5RqNHptDvAxA72Q/0, createdBy=a82a1611288, createdName=yydlt, createdTime=Tue Apr 21 13:49:00 CST 2015, time=2015-04-21, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=21552, encodeId=524a2155293, content=急性会厌炎是喉科的急重症之一,主要表现为全身中毒症状、吞咽及呼吸困难。有窒息的风险,须处理及时治疗处理以尽快控制炎症的发展。, beContent=null, objectType=article, channel=null, level=null, likeNumber=75, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=91c51554277, createdName=jbliufj, createdTime=Tue Apr 21 11:56:00 CST 2015, time=2015-04-21, status=1, ipAttribution=)]
    2016-08-07 刘煜

    积极检查治疗,防止喉阻塞。

    0

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    2015-05-31 Medxie

    儿童的更凶险,要密切关注

    0

  5. [GetPortalCommentsPageByObjectIdResponse(id=137922, encodeId=863613e92226, content=处理起来,蛮困难, beContent=null, objectType=article, channel=null, level=null, likeNumber=87, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/NUyjXTCJjo6KcicAVC1MwuHuBzGfFa0ZqPJYqr8iciaolWKTYMBxib5icxqsU2OEBYjj5ticwp82e8Zwx1luhoXzErojvkibyVwMF6O/0, createdBy=daf91941768, createdName=double19999, createdTime=Fri Sep 30 12:04:09 CST 2016, time=2016-09-30, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=96587, encodeId=3ca29658e26, content=积极检查治疗,防止喉阻塞。, beContent=null, objectType=article, channel=null, level=null, likeNumber=98, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://cdnapi.center.medsci.cn/medsci/head/2017/04/21/72142930668371951a41ef4ea4b233e6.jpg, createdBy=dcbc1715228, createdName=刘煜, createdTime=Sun Aug 07 06:06:00 CST 2016, time=2016-08-07, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1664853, encodeId=1977166485354, content=<a href='/topic/show?id=13792580544' target=_blank style='color:#2F92EE;'>#会厌炎#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=0, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=25805, encryptionId=13792580544, topicName=会厌炎)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=1dfe25855341, createdName=ms1692810954239974, createdTime=Fri Mar 18 13:35:00 CST 2016, time=2016-03-18, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=25447, encodeId=ff682544ec4, content=儿童的更凶险,要密切关注, beContent=null, objectType=article, channel=null, level=null, likeNumber=133, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=934b1626634, createdName=Medxie, createdTime=Sun May 31 07:04:00 CST 2015, time=2015-05-31, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=21557, encodeId=187a2155e9c, content=碰但了一列,但是还要小心,处理不好很容易出问题!, beContent=null, objectType=article, channel=null, level=null, likeNumber=167, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/ajNVdqHZLLCEEr4dM45RatXXGAkFCicnNYiasFiaRicicO1YWsIeTFOhgapauqib8Z8TChNB3ttVC5RqNHptDvAxA72Q/0, createdBy=a82a1611288, createdName=yydlt, createdTime=Tue Apr 21 13:50:00 CST 2015, time=2015-04-21, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=21556, encodeId=a9ab21556f2, content=即使气管切开吧!, beContent=null, objectType=article, channel=null, level=null, likeNumber=119, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/ajNVdqHZLLCEEr4dM45RatXXGAkFCicnNYiasFiaRicicO1YWsIeTFOhgapauqib8Z8TChNB3ttVC5RqNHptDvAxA72Q/0, createdBy=a82a1611288, createdName=yydlt, createdTime=Tue Apr 21 13:49:00 CST 2015, time=2015-04-21, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=21552, encodeId=524a2155293, content=急性会厌炎是喉科的急重症之一,主要表现为全身中毒症状、吞咽及呼吸困难。有窒息的风险,须处理及时治疗处理以尽快控制炎症的发展。, beContent=null, objectType=article, channel=null, level=null, likeNumber=75, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=91c51554277, createdName=jbliufj, createdTime=Tue Apr 21 11:56:00 CST 2015, time=2015-04-21, status=1, ipAttribution=)]
    2015-04-21 yydlt

    碰但了一列,但是还要小心,处理不好很容易出问题!

    0

  6. [GetPortalCommentsPageByObjectIdResponse(id=137922, encodeId=863613e92226, content=处理起来,蛮困难, beContent=null, objectType=article, channel=null, level=null, likeNumber=87, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/NUyjXTCJjo6KcicAVC1MwuHuBzGfFa0ZqPJYqr8iciaolWKTYMBxib5icxqsU2OEBYjj5ticwp82e8Zwx1luhoXzErojvkibyVwMF6O/0, createdBy=daf91941768, createdName=double19999, createdTime=Fri Sep 30 12:04:09 CST 2016, time=2016-09-30, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=96587, encodeId=3ca29658e26, content=积极检查治疗,防止喉阻塞。, beContent=null, objectType=article, channel=null, level=null, likeNumber=98, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://cdnapi.center.medsci.cn/medsci/head/2017/04/21/72142930668371951a41ef4ea4b233e6.jpg, createdBy=dcbc1715228, createdName=刘煜, createdTime=Sun Aug 07 06:06:00 CST 2016, time=2016-08-07, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1664853, encodeId=1977166485354, content=<a href='/topic/show?id=13792580544' target=_blank style='color:#2F92EE;'>#会厌炎#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=0, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=25805, encryptionId=13792580544, topicName=会厌炎)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=1dfe25855341, createdName=ms1692810954239974, createdTime=Fri Mar 18 13:35:00 CST 2016, time=2016-03-18, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=25447, encodeId=ff682544ec4, content=儿童的更凶险,要密切关注, beContent=null, objectType=article, channel=null, level=null, likeNumber=133, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=934b1626634, createdName=Medxie, createdTime=Sun May 31 07:04:00 CST 2015, time=2015-05-31, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=21557, encodeId=187a2155e9c, content=碰但了一列,但是还要小心,处理不好很容易出问题!, beContent=null, objectType=article, channel=null, level=null, likeNumber=167, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/ajNVdqHZLLCEEr4dM45RatXXGAkFCicnNYiasFiaRicicO1YWsIeTFOhgapauqib8Z8TChNB3ttVC5RqNHptDvAxA72Q/0, createdBy=a82a1611288, createdName=yydlt, createdTime=Tue Apr 21 13:50:00 CST 2015, time=2015-04-21, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=21556, encodeId=a9ab21556f2, content=即使气管切开吧!, beContent=null, objectType=article, channel=null, level=null, likeNumber=119, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/ajNVdqHZLLCEEr4dM45RatXXGAkFCicnNYiasFiaRicicO1YWsIeTFOhgapauqib8Z8TChNB3ttVC5RqNHptDvAxA72Q/0, createdBy=a82a1611288, createdName=yydlt, createdTime=Tue Apr 21 13:49:00 CST 2015, time=2015-04-21, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=21552, encodeId=524a2155293, content=急性会厌炎是喉科的急重症之一,主要表现为全身中毒症状、吞咽及呼吸困难。有窒息的风险,须处理及时治疗处理以尽快控制炎症的发展。, beContent=null, objectType=article, channel=null, level=null, likeNumber=75, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=91c51554277, createdName=jbliufj, createdTime=Tue Apr 21 11:56:00 CST 2015, time=2015-04-21, status=1, ipAttribution=)]
    2015-04-21 yydlt

    即使气管切开吧!

    0

  7. [GetPortalCommentsPageByObjectIdResponse(id=137922, encodeId=863613e92226, content=处理起来,蛮困难, beContent=null, objectType=article, channel=null, level=null, likeNumber=87, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/NUyjXTCJjo6KcicAVC1MwuHuBzGfFa0ZqPJYqr8iciaolWKTYMBxib5icxqsU2OEBYjj5ticwp82e8Zwx1luhoXzErojvkibyVwMF6O/0, createdBy=daf91941768, createdName=double19999, createdTime=Fri Sep 30 12:04:09 CST 2016, time=2016-09-30, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=96587, encodeId=3ca29658e26, content=积极检查治疗,防止喉阻塞。, beContent=null, objectType=article, channel=null, level=null, likeNumber=98, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://cdnapi.center.medsci.cn/medsci/head/2017/04/21/72142930668371951a41ef4ea4b233e6.jpg, createdBy=dcbc1715228, createdName=刘煜, createdTime=Sun Aug 07 06:06:00 CST 2016, time=2016-08-07, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1664853, encodeId=1977166485354, content=<a href='/topic/show?id=13792580544' target=_blank style='color:#2F92EE;'>#会厌炎#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=0, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=25805, encryptionId=13792580544, topicName=会厌炎)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=1dfe25855341, createdName=ms1692810954239974, createdTime=Fri Mar 18 13:35:00 CST 2016, time=2016-03-18, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=25447, encodeId=ff682544ec4, content=儿童的更凶险,要密切关注, beContent=null, objectType=article, channel=null, level=null, likeNumber=133, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=934b1626634, createdName=Medxie, createdTime=Sun May 31 07:04:00 CST 2015, time=2015-05-31, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=21557, encodeId=187a2155e9c, content=碰但了一列,但是还要小心,处理不好很容易出问题!, beContent=null, objectType=article, channel=null, level=null, likeNumber=167, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/ajNVdqHZLLCEEr4dM45RatXXGAkFCicnNYiasFiaRicicO1YWsIeTFOhgapauqib8Z8TChNB3ttVC5RqNHptDvAxA72Q/0, createdBy=a82a1611288, createdName=yydlt, createdTime=Tue Apr 21 13:50:00 CST 2015, time=2015-04-21, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=21556, encodeId=a9ab21556f2, content=即使气管切开吧!, beContent=null, objectType=article, channel=null, level=null, likeNumber=119, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/ajNVdqHZLLCEEr4dM45RatXXGAkFCicnNYiasFiaRicicO1YWsIeTFOhgapauqib8Z8TChNB3ttVC5RqNHptDvAxA72Q/0, createdBy=a82a1611288, createdName=yydlt, createdTime=Tue Apr 21 13:49:00 CST 2015, time=2015-04-21, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=21552, encodeId=524a2155293, content=急性会厌炎是喉科的急重症之一,主要表现为全身中毒症状、吞咽及呼吸困难。有窒息的风险,须处理及时治疗处理以尽快控制炎症的发展。, beContent=null, objectType=article, channel=null, level=null, likeNumber=75, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=91c51554277, createdName=jbliufj, createdTime=Tue Apr 21 11:56:00 CST 2015, time=2015-04-21, status=1, ipAttribution=)]
    2015-04-21 jbliufj

    急性会厌炎是喉科的急重症之一,主要表现为全身中毒症状、吞咽及呼吸困难。有窒息的风险,须处理及时治疗处理以尽快控制炎症的发展。

    0

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