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Sci Rep：成人早发型糖尿病的特征有哪些？

2017-04-21 MedSci MedSci原创

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近期，一项发表在杂志Sci Rep上的研究评估了中国人群新诊断的早发型糖尿病的特征，对全国横断面调查中2801例未确定糖尿病或糖尿病前期的糖尿病患者进行了分析。此项研究根据糖尿病发病的年龄，将参与者分为四类（22-43岁、44-52岁、53-61岁和> 61岁），其中将第一组受试者定义为早发型糖尿病组。早发型糖尿病组患者的收缩压（SBP）、总胆固醇、低密度脂蛋白、餐后2小时血糖和尿白蛋白肌酐

近期，一项发表在杂志Sci Rep上的研究评估了中国人群新诊断的早发型糖尿病的特征，对全国横断面调查中2801例未确定糖尿病或糖尿病前期的糖尿病患者进行了分析。

此项研究根据糖尿病发病的年龄，将参与者分为四类（22-43岁、44-52岁、53-61岁和> 61岁），其中将第一组受试者定义为早发型糖尿病组。

早发型糖尿病组患者的收缩压（SBP）、总胆固醇、低密度脂蛋白、餐后2小时血糖和尿白蛋白肌酐比例均较低。

早发型糖尿病患者和其他年龄组患者之间的体重指数、稳态模型评估（HOMA）的β细胞功能和糖尿病家族史没有差异。

胰岛素抵抗（IR）的HOMA评分和葡萄糖负荷后30分钟的DI指数（DI30）在早发型糖尿病患者中升高。

早发型糖尿病患者的β细胞功能下降更为恶化。男性、甘油三酯、HOMA-IR和DI30与早期诊断的年龄呈正相关。

此项研究表明：与年龄较大的糖尿病患者相比，年龄较轻时诊断为糖尿病的患者，特征在于具有类似的心血管风险，胰岛素抵抗增加，并且β细胞功能衰竭的程度更严重。

原始出处：
Zou X, Zhou X, et al. The characteristics of newly diagnosed adult early-onset diabetes: a population-based cross-sectional study. Sci Rep. 2017 Apr 19;7:46534. doi: 10.1038/srep46534.

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    2018-01-19 ms7258648636991762

    #早发#

    0

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    2017-04-30 绛珠草小姐

    学习了，谢谢分享

    0

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    2017-04-28 绛珠草小姐

    学习了，谢谢分享

    0

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    2017-04-27 1e1b0e77m05(暂无匿称)

    早期诊断出糖尿病有点困难

    0

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    2017-04-25 1def5ccfm69(暂无匿称)

    学习了

    0

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    2017-04-23 虈亣靌

    学习了很好的内容

    0

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    2017-04-22 爹

    糖尿病早期应该还是要重视

    0

  8. [GetPortalCommentsPageByObjectIdResponse(id=1664029, encodeId=a6d61664029cb, content=<a href='/topic/show?id=a20c59283e5' target=_blank style='color:#2F92EE;'>#早发#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=53, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=59283, encryptionId=a20c59283e5, topicName=早发)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=06c425715601, createdName=ms7258648636991762, createdTime=Fri Jan 19 06:04:00 CST 2018, time=2018-01-19, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=192139, encodeId=8cd81921398b, content=学习了，谢谢分享, beContent=null, objectType=article, channel=null, level=null, likeNumber=63, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://q.qlogo.cn/qqapp/101296147/1A51842815047D40BFDAA8D69AA8E519/100, createdBy=fd7f2029163, createdName=绛珠草小姐, createdTime=Sun Apr 30 11:43:25 CST 2017, time=2017-04-30, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=191481, encodeId=42dc1914815b, content=学习了，谢谢分享, beContent=null, objectType=article, channel=null, level=null, likeNumber=61, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://q.qlogo.cn/qqapp/101296147/1A51842815047D40BFDAA8D69AA8E519/100, createdBy=fd7f2029163, createdName=绛珠草小姐, createdTime=Fri Apr 28 13:09:10 CST 2017, time=2017-04-28, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=191080, encodeId=2a9a191080b1, content=早期诊断出糖尿病有点困难, beContent=null, objectType=article, channel=null, level=null, likeNumber=76, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/ajNVdqHZLLAVv1veDKlI7ISDgWM6lGCNl8WQ0dzGibseiaBhpxICLBMmoiaMuOBljYmFYwLUcKXiblicL4eJiauKEic2g/0, createdBy=ef751994234, createdName=1e1b0e77m05(暂无匿称), createdTime=Thu Apr 27 11:37:47 CST 2017, time=2017-04-27, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=190337, encodeId=dea019033ee5, content=学习了, beContent=null, objectType=article, channel=null, level=null, likeNumber=83, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/oLAjfB7s1ib01ticx4P4peVO79gkOckmWQ4AOTZCu4TmH8Tib2WjYEo4A6sic8141se9bNsJyib0mdql9GFpXXNLfFXeibOCZ6HoGY/0, createdBy=78281734442, createdName=1def5ccfm69(暂无匿称), createdTime=Tue Apr 25 05:45:19 CST 2017, time=2017-04-25, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=190006, encodeId=e36919000613, content=学习了很好的内容, beContent=null, objectType=article, channel=null, level=null, likeNumber=59, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/mONcle9pic3zMoyicyo6ia9f4IuLQAwZoxD6Hx4ibd5CMcOCYhStY6oDibbKK6O2X8iaicldO5ib8j1iapOIobIKCGiczU2A/0, createdBy=56251941490, createdName=虈亣靌, createdTime=Sun Apr 23 23:48:06 CST 2017, time=2017-04-23, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=189520, encodeId=0d5d18952004, content=糖尿病早期应该还是要重视, beContent=null, objectType=article, channel=null, level=null, likeNumber=41, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/Q3auHgzwzM7VqWONeiaUtbbiakTte9c8LKljRjI1rydjLKBNq2lIn28vTvzCVP2ZAdLTC7m4PVibicxRyFj4R2GDzVQazjCyupTTUjX3OB06PAw/0, createdBy=b2bd1952121, createdName=爹, createdTime=Sat Apr 22 01:14:14 CST 2017, time=2017-04-22, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=189376, encodeId=c6401893e657, content=学习了谢谢了。, beContent=null, objectType=article, channel=null, level=null, likeNumber=57, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/mONcle9pic3zSn0GqHrsfLPeNmuNF9ibgMfMOAs7Iic5MpiaU8RLmRH67xCKuk5wzfhb7G4ib7ia6z9lrnsTicj1nAUfEOMecZDtvvu/0, createdBy=d7f91939785, createdName=186****0580(小山羊）, createdTime=Fri Apr 21 14:19:05 CST 2017, time=2017-04-21, status=1, ipAttribution=)]
    2017-04-21 186****0580(小山羊）

    学习了谢谢了。

    0

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