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Gastrointest Endosc:内镜治疗肠化生完全缓解后复发率高

2016-06-06 高晓方 翻译 中国医学论坛报

美国一项研究表明,内镜治疗肠化生完全缓解(CRIM)后复发率高,因此,CRIM后的持续监测很有必要。论文发表于《消化内镜》杂志6月刊[Gastrointest Endosc2016,83(6):1090]。 该研究检索多个数据库中内镜治疗CRIM后的长期随访研究,估算CRIM后复发性肠化生、不典型增生Barrett食管和高度不典型增生(HGD)或食管腺癌(EAC)每人-年随访的汇总发病率,评估

美国一项研究表明,内镜治疗肠化生完全缓解(CRIM)后复发率高,因此,CRIM后的持续监测很有必要。论文发表于《消化内镜》杂志6月刊[Gastrointest Endosc 2016,83(6):1090]。

该研究检索多个数据库中内镜治疗CRIM后的长期随访研究,估算CRIM后复发性肠化生、不典型增生Barrett食管和高度不典型增生(HGD)或食管腺癌(EAC)每人-年随访的汇总发病率,评估与复发相关的因素。

结果显示,41项研究的4443例患者符合入选标准,随访超过10427人-年,复发患者为795例。所有内镜治疗模式,复发性肠化生、不典型增生Barrett食管和HGD或EAC每人-年的汇总发病率分别为7.1%、1.3%和0.8%。患者年龄的增加和Barrett食管的病变长度可预测肠化生复发;内镜治疗后复发率为97%。

原始出处:

Krishnamoorthi R1, Singh S1, Ragunathan K2, A Katzka D1, K Wang K1, G Iyer P1.Risk of recurrence of Barrett's esophagus after successful endoscopic therapy.Gastrointest Endosc. 2016.

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    2016-12-14 许安
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    2017-04-22 lqvr
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    2016-06-08 楚钟

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