BMC Cancer：不想患结直肠癌？多吃含钙物质！

2015-12-21 Seven L 译 MedSci原创

摄入高剂量的饮食钙被认为具有预防直肠癌的作用，研究者对日常饮食钙摄入非常低的韩国人进行了一项病例对照研究，探究饮食钙摄入和结直肠癌风险间的剂量反应关系。该研究纳入了2010年8月-2013年8月诊断为结直肠癌的患者，同时纳入对照组。通过半定量食物频度问卷调查采集参与者饮食钙摄入情况，并根据癌症位置将其分为结肠癌、远端结肠癌和直肠癌。使用二元和多分类回归分析模型评估饮食钙摄入量和结直肠癌风险间联系。

摄入高剂量的饮食钙被认为具有预防直肠癌的作用，研究者对日常饮食钙摄入非常低的韩国人进行了一项病例对照研究，探究饮食钙摄入和结直肠癌风险间的剂量反应关系。

该研究纳入了2010年8月-2013年8月诊断为结直肠癌的患者，同时纳入了对照组。通过半定量食物频度问卷调查采集参与者饮食钙摄入情况，并根据癌症位置将其分为结肠癌、远端结肠癌和直肠癌。使用二元和多分类回归分析模型评估饮食钙摄入量和结直肠癌风险间联系。

最后的分析数据来自922名结直肠癌患者，以及2766名对照组。无论男女，饮食钙摄入量最高的四分之一群体比最低的四分之一群体，其结直肠癌风险显著下降（男：OR=0.16，95% CI 0.11-0.24；女：OR= 0.16，95% CI 0.09-0.29）。无论是结肠癌、远端结肠癌还是直肠癌，饮食钙摄入量最高的四分之一人群，无论男女，其癌症风险均降低。

韩国人比西方人日常钙摄入量更低，对韩国人的研究表明，饮食钙摄入量越高，患结直肠癌风险越低。无论男女，无论结直肠癌位置，摄入更高含量的饮食钙，癌症风险均降低。

原始出处：

Han C, Shin A,et al.Dietary calcium intake and the risk of colorectal cancer: a case control study.BMC Cancer. 2015 Dec 16;15(1):966.

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继续努力

136 0
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2016-04-24 忠诚向上

继续努力

154 0
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2016-04-24 忠诚向上

继续努力

98 0
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2016-04-24 忠诚向上

继续努力

209 0
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2016-04-24 忠诚向上

继续努力

80 0
[GetPortalCommentsPageByObjectIdResponse(id=1974648, encodeId=c83319e4648ff, content=<a href='/topic/show?id=f145355379' target=_blank style='color:#2F92EE;'>#BMC#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=61, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=3553, encryptionId=f145355379, topicName=BMC)], attachment=null, authenticateStatus=null, createdAvatar=https://thirdqq.qlogo.cn/qqapp/101173734/363C99735735B7F4CB11D5F78F580525/100, createdBy=aab22500211, createdName=ms3025846204744509, createdTime=Fri Feb 12 21:11:00 CST 2016, time=2016-02-12, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=82443, encodeId=946d82443e5, content=继续努力, beContent=null, objectType=article, channel=null, level=null, likeNumber=133, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=45101626056, createdName=忠诚向上, createdTime=Sun Apr 24 11:36:00 CST 2016, time=2016-04-24, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=82442, encodeId=14bf82442fb, content=继续努力, beContent=null, objectType=article, channel=null, level=null, likeNumber=211, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=45101626056, createdName=忠诚向上, createdTime=Sun Apr 24 11:36:00 CST 2016, time=2016-04-24, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=82441, encodeId=b67d8244123, content=继续努力, beContent=null, objectType=article, channel=null, level=null, likeNumber=136, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=45101626056, createdName=忠诚向上, createdTime=Sun Apr 24 11:36:00 CST 2016, time=2016-04-24, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=82440, encodeId=1950824406e, content=继续努力, beContent=null, objectType=article, channel=null, level=null, likeNumber=154, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=45101626056, createdName=忠诚向上, createdTime=Sun Apr 24 11:36:00 CST 2016, time=2016-04-24, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=82433, encodeId=9d8b824339c, content=继续努力, beContent=null, objectType=article, channel=null, level=null, likeNumber=98, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=45101626056, createdName=忠诚向上, createdTime=Sun Apr 24 11:35:00 CST 2016, time=2016-04-24, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=82432, encodeId=45f28243221, content=继续努力, beContent=null, objectType=article, channel=null, level=null, likeNumber=209, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=45101626056, createdName=忠诚向上, createdTime=Sun Apr 24 11:35:00 CST 2016, time=2016-04-24, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=82434, encodeId=0c1c8243404, content=继续努力, beContent=null, objectType=article, channel=null, level=null, likeNumber=80, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=45101626056, createdName=忠诚向上, createdTime=Sun Apr 24 11:35:00 CST 2016, time=2016-04-24, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=82435, encodeId=53cc82435d3, content=继续努力, beContent=null, objectType=article, channel=null, level=null, likeNumber=79, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=45101626056, createdName=忠诚向上, createdTime=Sun Apr 24 11:35:00 CST 2016, time=2016-04-24, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=82438, encodeId=1e0f82438e9, content=继续努力, beContent=null, objectType=article, channel=null, level=null, likeNumber=113, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=45101626056, createdName=忠诚向上, createdTime=Sun Apr 24 11:35:00 CST 2016, time=2016-04-24, status=1, ipAttribution=)]
2016-04-24 忠诚向上

继续努力

79 0
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2016-04-24 忠诚向上

继续努力

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