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PLos One:炎症性肠病患者的生活保健费用和住院费用

2017-05-13 MedSci MedSci原创

寿命终止(EOL)的护理需要很大的成本,特别是急性护理服务。在炎症性肠病(IBD)患者中,由于依赖医院服务和昂贵的诊断测试和治疗,EOL的成本可能会更多。近期,一项发表在杂志PLos One上的研究旨在比较IBD与非IBD患者之间的EOL医疗保健用途和成本。研究者们使用相关的健康管理数据,对2010年至2013年期间加拿大安大略省所有死亡人员进行了回顾性队列研究。对IBD(N = 2,214)和非

寿命终止(EOL)的护理需要很大的成本,特别是急性护理服务。在炎症性肠病IBD)患者中,由于依赖医院服务和昂贵的诊断测试和治疗,EOL的成本可能会更多。近期,一项发表在杂志PLos One上的研究旨在比较IBD与非IBD患者之间的EOL医疗保健用途和成本。


研究者们使用相关的健康管理数据,对2010年至2013年期间加拿大安大略省所有死亡人员进行了回顾性队列研究。对IBD(N = 2,214)和非IBD(N = 262,540)的死亡人数进行了比较,分析了最后90天生命的住院时间以及最后一年的直接医疗费用总额。

此项研究结果显示:在生命的最后90天中,IBD患者在医院平均时间为16天,与非IBD患者相比,是其调整后医院天数2.1倍(95%置信区间[CI] 1.5-2.8天)。 

IBD诊断与最后一年调整后的每位患者成本相比,增加了7,210加元(95%CI $ 5,005- $ 9,464),其中76%是由于住院费用过高。IBD护理的EOL成本高于16项研究慢性疾病中的15项。医疗保健费用在最后的90天内大幅上涨,主要是由于住院费用上升。

此项研究结果表明:IBD患者在接近EOL时,花费更多的时间在医院,并承受比其他患者更大的医疗保健费用。

原始出处:
Murthy SK, James PD, et al. High end of life health care costs and hospitalization burden in inflammatory bowel disease patients: A population-based study. PLoS One. 2017 May 12;12(5):e0177211. doi: 10.1371/journal.pone.0177211. eCollection 2017. 

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    2017-07-06 lofter

    学习了,感谢分享

    0

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createdAvatar=https://wx.qlogo.cn/mmopen/NUyjXTCJjo6KcicAVC1MwuK9CDibOwszLoEBg36ZXqzB5NDasNV9GTfFDmBicM1V8hUS4OtTicG3IiaFIKq4wqD23LUxORRJXqjVs/0, createdBy=00e81647535, createdName=I come, createdTime=Fri Jun 09 22:16:14 CST 2017, time=2017-06-09, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=205426, encodeId=16b620542638, content=学习了谢谢分享, beContent=null, objectType=article, channel=null, level=null, likeNumber=108, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/oLAjfB7s1ib06iaV3D9Tg5KwlM29ic8TDJMJOiarryMIZZhTjXxyRT9lffSWpWWcWojnL7ibJwcOn99ayict8FJ9ICYmNh9swD6R4E/0, createdBy=196f1683049, createdName=收获你的美, createdTime=Fri Jun 02 05:30:52 CST 2017, time=2017-06-02, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=201361, encodeId=d972201361f8, content=学习了,多谢分享, beContent=null, objectType=article, channel=null, level=null, likeNumber=100, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=84e21956153, createdName=1e1263e3m20(暂无匿称), createdTime=Mon May 22 23:45:48 CST 2017, time=2017-05-22, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=200562, encodeId=582e2005629d, content=炎症性肠病费钱, beContent=null, objectType=article, channel=null, level=null, likeNumber=109, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/NUyjXTCJjo6KcicAVC1MwuK9CDibOwszLoEBg36ZXqzB5NDasNV9GTfFDmBicM1V8hUS4OtTicG3IiaFIKq4wqD23LUxORRJXqjVs/0, createdBy=00e81647535, createdName=I come, createdTime=Sat May 20 21:33:54 CST 2017, time=2017-05-20, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=199600, encodeId=d644199600b9, content=学习了,谢谢, beContent=null, objectType=article, channel=null, level=null, likeNumber=76, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/NUyjXTCJjo6KcicAVC1MwuOWcPEsEP4FrvDcicue5V6rMkmXmY73KjYP59vQrEdjU89iaN4ZkOhsItlHkmGTjhV3b5S3zOQA4E0/0, createdBy=cc261682151, createdName=卡圣, createdTime=Thu May 18 12:41:07 CST 2017, time=2017-05-18, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=199568, encodeId=0918199568ee, content=学习了谢谢分享, beContent=null, objectType=article, channel=null, level=null, likeNumber=89, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=c0a61971598, createdName=往日如昨, createdTime=Thu May 18 09:58:33 CST 2017, time=2017-05-18, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=198678, encodeId=29291986e8f2, content=炎症性肠病患者的生活保健费用。, beContent=null, objectType=article, channel=null, level=null, likeNumber=74, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://cacheapi.medsci.cn/resource/upload/20160806/IMG57A5698BDB0244113.jpg, createdBy=32a91358059, createdName=jyzxjiangqin, createdTime=Tue May 16 07:24:34 CST 2017, time=2017-05-16, status=1, ipAttribution=)]
    2017-06-09 I come

    学习了谢谢分享

    0

  5. 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    2017-06-02 收获你的美

    学习了谢谢分享

    0

  6. 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attachment=null, authenticateStatus=null, createdAvatar=http://cacheapi.medsci.cn/resource/upload/20160806/IMG57A5698BDB0244113.jpg, createdBy=32a91358059, createdName=jyzxjiangqin, createdTime=Tue May 16 07:24:34 CST 2017, time=2017-05-16, status=1, ipAttribution=)]
    2017-05-22 1e1263e3m20(暂无匿称)

    学习了,多谢分享

    0

  7. 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attachment=null, authenticateStatus=null, createdAvatar=http://cacheapi.medsci.cn/resource/upload/20160806/IMG57A5698BDB0244113.jpg, createdBy=32a91358059, createdName=jyzxjiangqin, createdTime=Tue May 16 07:24:34 CST 2017, time=2017-05-16, status=1, ipAttribution=)]
    2017-05-20 I come

    炎症性肠病费钱

    0

  8. 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topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/NUyjXTCJjo6KcicAVC1MwuOWcPEsEP4FrvDcicue5V6rMkmXmY73KjYP59vQrEdjU89iaN4ZkOhsItlHkmGTjhV3b5S3zOQA4E0/0, createdBy=cc261682151, createdName=卡圣, createdTime=Thu May 18 12:41:07 CST 2017, time=2017-05-18, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=199568, encodeId=0918199568ee, content=学习了谢谢分享, beContent=null, objectType=article, channel=null, level=null, likeNumber=89, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=c0a61971598, createdName=往日如昨, createdTime=Thu May 18 09:58:33 CST 2017, time=2017-05-18, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=198678, encodeId=29291986e8f2, content=炎症性肠病患者的生活保健费用。, beContent=null, objectType=article, channel=null, level=null, likeNumber=74, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://cacheapi.medsci.cn/resource/upload/20160806/IMG57A5698BDB0244113.jpg, createdBy=32a91358059, createdName=jyzxjiangqin, createdTime=Tue May 16 07:24:34 CST 2017, time=2017-05-16, status=1, ipAttribution=)]
    2017-05-18 卡圣

    学习了,谢谢

    0

  9. 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    2017-05-18 往日如昨

    学习了谢谢分享

    0

  10. 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    2017-05-16 jyzxjiangqin

    炎症性肠病患者的生活保健费用。

    0

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现实生活中的一项多中心队列研究表明:对于异常结构的监测,靶向活检的色素内镜检查(CE)优于白光内镜。 此外,使用CE进行活体光学诊断时,对于发育不良的排除诊断,准确度十分高,特别是内镜医师专家进行检查时。 该研究共纳入了350名IBD患者,其中女性占47%,UC患者占78%,平均IBD持续时间为17年;这些患者接受了标准模式的白光内镜(41.5%)或高清白光内镜(58.5%);随后使用

Gut:CD177+中性粒细胞负性调节IBD!

由此可见,CD177+中性粒细胞是具有功能活性的亚群,在IBD中通过增加杀菌活性和IL-22的生产来发挥保护作用。针对CD177+中性粒细胞的治疗策略可能有益于IBD的治疗。

Gastroenterology:英夫利昔单抗暴露与IBD小儿患者发生恶性肿瘤或HLH的风险增加无关!

来自于大型临床试验和SEER数据库的数据得到的对年龄、性别和种族进行调整后的SIRs,研究人员发现英夫利昔单抗暴露与IBD小儿患者发生恶性肿瘤或HLH的风险增加无关。巯基嘌呤暴露是IBD小儿患者发生恶性肿瘤或HLH的一个重要前提事件。

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