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Lancet oncol:良好生活方式确能延缓衰老

2013-09-29 佚名 《柳叶刀—肿瘤学》

人们都知道健康饮食、适量运动对身体有好处。一项最新研究从细胞老化角度进一步证实,保持良好的生活方式,的确能延缓衰老。 据介绍,人体细胞内的染色体上有称作端粒的结构,它好比鞋带两头防止磨损的“保护帽”。人出生时,染色体端粒都有一定长度。随着细胞不断分裂和老化,端粒会慢慢变短。因此,端粒长度被用作判断衰老程度的重要标志。 英国新一期《柳叶刀—肿瘤》杂志刊登美国研究人员的论文说,一项有35名前列腺癌

人们都知道健康饮食、适量运动对身体有好处。一项最新研究从细胞老化角度进一步证实,保持良好的生活方式,的确能延缓衰老。

据介绍,人体细胞内的染色体上有称作端粒的结构,它好比鞋带两头防止磨损的“保护帽”。人出生时,染色体端粒都有一定长度。随着细胞不断分裂和老化,端粒会慢慢变短。因此,端粒长度被用作判断衰老程度的重要标志。

英国新一期《柳叶刀—肿瘤》杂志刊登美国研究人员的论文说,一项有35名前列腺癌患者参加的长期跟踪研究,在5年的时间里,其中一组志愿者按要求完成饮食、运动、压力调节等全方位的积极改变,另一组作为对照。结果发现,积极作出改变的一组人的端粒长度平均延长了约10%,而对照组则平均缩短了约3%。

研究人员介绍说,这项研究提到的积极生活方式包括:多吃富含果蔬、豆类和谷物的食品,减少碳水化合物和油脂摄入;坚持中等强度的有氧运动,如每天散步半小时;练习瑜伽或进行呼吸训练、冥想等舒缓压力的活动;定期参加心理医生组织的团体性“社会支持”活动等。

领导这项研究的加利福尼亚大学旧金山分校教授迪恩。奥尼什说,虽然这项研究的对象是前列腺癌患者,研究结果应该同样可推及健康男性和女性,即保持健康生活方式可延缓端粒缩短进程。研究人员下一步将开展大规模随机对照研究,进一步确认这一效果。

原文阅读

Ornish D, Lin J, Chan JM, Epel E, Kemp C, Weidner G, Marlin R, Frenda SJ, Magbanua MJ, Daubenmier J, Estay I, Hills NK, Chainani-Wu N, Carroll PR, Blackburn EH.Effect of comprehensive lifestyle changes on telomerase activity and telomere length in men with biopsy-proven low-risk prostate cancer: 5-year follow-up of a descriptive pilot study.Lancet Oncol. 2013 Sep 16.

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  3. [GetPortalCommentsPageByObjectIdResponse(id=1932363, encodeId=0e81193236386, content=<a href='/topic/show?id=d8de4951168' target=_blank style='color:#2F92EE;'>#延缓衰老#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=64, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=49511, encryptionId=d8de4951168, topicName=延缓衰老)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=7f52347, createdName=soongzhihua, createdTime=Tue Apr 15 02:45:00 CST 2014, time=2014-04-15, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1827622, encodeId=051f182e62204, content=<a href='/topic/show?id=1b6210686b2' target=_blank style='color:#2F92EE;'>#Lancet#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=59, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=10686, encryptionId=1b6210686b2, topicName=Lancet)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=395f25, createdName=爆笑小医, createdTime=Sun Dec 01 14:45:00 CST 2013, time=2013-12-01, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1864484, encodeId=b7df186448422, content=<a href='/topic/show?id=16ce133504e' target=_blank style='color:#2F92EE;'>#Oncol#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=73, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=13350, encryptionId=16ce133504e, topicName=Oncol)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=b63894, createdName=minlingfeng, createdTime=Mon Nov 11 14:45:00 CST 2013, time=2013-11-11, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=6183, encodeId=b579618356, content=无语研究,但是人家发SCI,这才是正点, beContent=null, objectType=article, channel=null, level=null, likeNumber=132, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://img.medsci.cn/20220519/c2ab253484ee4527a2d4e9589a4821ac/45de9bf494a54becb2ea4369c9d11e85.jpg, createdBy=7a3710, createdName=lovetcm, createdTime=Mon Sep 30 19:11:00 CST 2013, time=2013-09-30, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=6181, encodeId=1b8b618105, content=112.114.12.234于2013-9-29 17:48:00 评论道: <br> 泥玛,这劳资早就知道了! <br> <br> 哈哈,楼上的正解!, beContent=null, objectType=article, channel=null, level=null, likeNumber=141, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://img.medsci.cn/20211213/a4233b110a314856b51b2ba7363cc1a1/02edceab314e4237aec74a0678eee6bf.jpg, createdBy=507370304, createdName=ellen0820, createdTime=Mon Sep 30 11:06:00 CST 2013, time=2013-09-30, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=6180, encodeId=fee36180e0, content=泥玛,这劳资早就知道了!, beContent=null, objectType=article, channel=null, level=null, likeNumber=128, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=f0620, createdName=112.114.12.234, createdTime=Sun Sep 29 17:48:00 CST 2013, time=2013-09-29, status=1, ipAttribution=)]
    2013-11-11 minlingfeng
  4. [GetPortalCommentsPageByObjectIdResponse(id=1932363, encodeId=0e81193236386, content=<a href='/topic/show?id=d8de4951168' target=_blank style='color:#2F92EE;'>#延缓衰老#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=64, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=49511, encryptionId=d8de4951168, topicName=延缓衰老)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=7f52347, createdName=soongzhihua, createdTime=Tue Apr 15 02:45:00 CST 2014, time=2014-04-15, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1827622, encodeId=051f182e62204, content=<a href='/topic/show?id=1b6210686b2' target=_blank style='color:#2F92EE;'>#Lancet#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=59, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=10686, encryptionId=1b6210686b2, topicName=Lancet)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=395f25, createdName=爆笑小医, createdTime=Sun Dec 01 14:45:00 CST 2013, time=2013-12-01, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1864484, encodeId=b7df186448422, content=<a href='/topic/show?id=16ce133504e' target=_blank style='color:#2F92EE;'>#Oncol#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=73, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=13350, encryptionId=16ce133504e, topicName=Oncol)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=b63894, createdName=minlingfeng, createdTime=Mon Nov 11 14:45:00 CST 2013, time=2013-11-11, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=6183, encodeId=b579618356, content=无语研究,但是人家发SCI,这才是正点, beContent=null, objectType=article, channel=null, level=null, likeNumber=132, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://img.medsci.cn/20220519/c2ab253484ee4527a2d4e9589a4821ac/45de9bf494a54becb2ea4369c9d11e85.jpg, createdBy=7a3710, createdName=lovetcm, createdTime=Mon Sep 30 19:11:00 CST 2013, time=2013-09-30, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=6181, encodeId=1b8b618105, content=112.114.12.234于2013-9-29 17:48:00 评论道: <br> 泥玛,这劳资早就知道了! <br> <br> 哈哈,楼上的正解!, beContent=null, objectType=article, channel=null, level=null, likeNumber=141, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://img.medsci.cn/20211213/a4233b110a314856b51b2ba7363cc1a1/02edceab314e4237aec74a0678eee6bf.jpg, createdBy=507370304, createdName=ellen0820, createdTime=Mon Sep 30 11:06:00 CST 2013, time=2013-09-30, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=6180, encodeId=fee36180e0, content=泥玛,这劳资早就知道了!, beContent=null, objectType=article, channel=null, level=null, likeNumber=128, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=f0620, createdName=112.114.12.234, createdTime=Sun Sep 29 17:48:00 CST 2013, time=2013-09-29, status=1, ipAttribution=)]
    2013-09-30 lovetcm

    无语研究,但是人家发SCI,这才是正点

    0

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    2013-09-30 ellen0820

    112.114.12.234于2013-9-29 17:48:00 评论道:
    泥玛,这劳资早就知道了!

    哈哈,楼上的正解!

    0

  6. [GetPortalCommentsPageByObjectIdResponse(id=1932363, encodeId=0e81193236386, content=<a href='/topic/show?id=d8de4951168' target=_blank style='color:#2F92EE;'>#延缓衰老#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=64, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=49511, encryptionId=d8de4951168, topicName=延缓衰老)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=7f52347, createdName=soongzhihua, createdTime=Tue Apr 15 02:45:00 CST 2014, time=2014-04-15, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1827622, encodeId=051f182e62204, content=<a href='/topic/show?id=1b6210686b2' target=_blank style='color:#2F92EE;'>#Lancet#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=59, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=10686, encryptionId=1b6210686b2, topicName=Lancet)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=395f25, createdName=爆笑小医, createdTime=Sun Dec 01 14:45:00 CST 2013, time=2013-12-01, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1864484, encodeId=b7df186448422, content=<a href='/topic/show?id=16ce133504e' target=_blank style='color:#2F92EE;'>#Oncol#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=73, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=13350, encryptionId=16ce133504e, topicName=Oncol)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=b63894, createdName=minlingfeng, createdTime=Mon Nov 11 14:45:00 CST 2013, time=2013-11-11, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=6183, encodeId=b579618356, content=无语研究,但是人家发SCI,这才是正点, beContent=null, objectType=article, channel=null, level=null, likeNumber=132, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://img.medsci.cn/20220519/c2ab253484ee4527a2d4e9589a4821ac/45de9bf494a54becb2ea4369c9d11e85.jpg, createdBy=7a3710, createdName=lovetcm, createdTime=Mon Sep 30 19:11:00 CST 2013, time=2013-09-30, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=6181, encodeId=1b8b618105, content=112.114.12.234于2013-9-29 17:48:00 评论道: <br> 泥玛,这劳资早就知道了! <br> <br> 哈哈,楼上的正解!, beContent=null, objectType=article, channel=null, level=null, likeNumber=141, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://img.medsci.cn/20211213/a4233b110a314856b51b2ba7363cc1a1/02edceab314e4237aec74a0678eee6bf.jpg, createdBy=507370304, createdName=ellen0820, createdTime=Mon Sep 30 11:06:00 CST 2013, time=2013-09-30, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=6180, encodeId=fee36180e0, content=泥玛,这劳资早就知道了!, beContent=null, objectType=article, channel=null, level=null, likeNumber=128, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=f0620, createdName=112.114.12.234, createdTime=Sun Sep 29 17:48:00 CST 2013, time=2013-09-29, status=1, ipAttribution=)]
    2013-09-29 112.114.12.234

    泥玛,这劳资早就知道了!

    0

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