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Lancet：烹饪和肺炎有啥关系?

2016-12-07 xing.T MedSci原创

儿童肺炎
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我们没有发现任何证据表明干预包括清洁生物燃料炉灶能够减少了马拉维农村儿童肺炎的风险。但是有效的策略以减少家庭空气污染的不利健康影响是必要的。

根据世界卫生组织估计，全球每年有超过400万的早产儿死亡，其中有50万5岁以下儿童死于肺炎，这些数据与烹饪时使用的固体燃料来源的空气污染有关。近日，顶级医学杂志Lancet上发表了一篇文章，研究人员假设，用清洁生物燃料替代明火炉灶将会降低儿童肺炎的发病率。 

研究人员进行了一项社区开放整群随机对照试验，来比较清洁生物燃料炉灶干预与继续使用明火炉灶对生活在马拉维两个地区Chikhwawa和Karonga的农村儿童肺炎的影响。使用计算机生成的随机数表与根据位置、到健康中心的距离、群体大小分层，将群体随机分配到干预组和对照组。在群体内，家里有4.5岁儿童的家庭有资格参加，发放给干预组家庭两个生物燃料的炉灶和一个太阳能电池板。主要结局为5岁以下的儿童发生WHO儿童疾病综合管理（IMCI）定义的肺炎情况。治疗意向性治疗用于进行疗效和安全性分析。该试验在ISRCTN进行注册，注册号为ISRCTN59448623。

研究者在2013年12月9日至2016年2月28日期间招募了来自150个群体8626户家庭的750名儿童。来自于8470户家庭的10,543名儿童为意向治疗分析提供了15,991名儿童/年的随访数据。干预组的IMCI肺炎发生率为每100名儿童15.76人/年（95%可信区间为14.89-16.63），对照组为100名儿童15.58人/年（95%可信区间为14.72-16.45），干预组比对照组发病率比值（IRR）为1.01（95%可信区间为0.91-1.13；P=0.80）。19名儿童出现了烹饪相关的严重不良事件（烧伤）；干预组9名和对照组10名（1名死亡）（IRR为0.91[95%可信区间为0.37-2.23]；P=0.83）。 

由此可见，我们没有发现任何证据表明干预包括清洁生物燃料炉灶能够减少了马拉维农村儿童肺炎的风险，但是有效的策略以减少家庭空气污染的不利健康影响是必要的。 

原始出处： 

Kevin Mortimer, et al. A cleaner burning biomass-fuelled cookstove intervention to prevent pneumonia in children under 5 years old in rural Malawi (the Cooking and Pneumonia Study): a cluster randomised controlled trial. Lancet.06 December 2016. 

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    2017-07-06 howi

    #Lancet#

    0

  2. [GetPortalCommentsPageByObjectIdResponse(id=1828699, encodeId=95171828699c0, content=<a href='/topic/show?id=1b6210686b2' target=_blank style='color:#2F92EE;'>#Lancet#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=69, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=10686, encryptionId=1b6210686b2, topicName=Lancet)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=3f0227, createdName=howi, createdTime=Thu Jul 06 03:01:00 CST 2017, time=2017-07-06, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1647160, encodeId=2fd5164e16083, content=<a href='/topic/show?id=02286e2683e' target=_blank style='color:#2F92EE;'>#烹饪#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=133, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=67268, encryptionId=02286e2683e, topicName=烹饪)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=b9e923392426, createdName=gao_jian4225, createdTime=Sat Apr 08 04:01:00 CST 2017, time=2017-04-08, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=163046, encodeId=e98616304615, content=需要全社会共同关注, beContent=null, objectType=article, channel=null, level=null, likeNumber=110, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/jW482SpianMayicTRbRZ5RzdAIB7UwTkHt6fQkBP8ictliaXtc5gCUmYdAW1sAETC2nhO3q6YjRHkUibyOCtP8ibmXNObTyd63A076/0, createdBy=d4111948983, createdName=1e10c84am36(暂无匿称), createdTime=Thu Dec 15 14:36:56 CST 2016, time=2016-12-15, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=162533, encodeId=f547162533c5, content=谢谢分享学习了, beContent=null, objectType=article, channel=null, level=null, likeNumber=99, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=e4e21675717, createdName=卡莲, createdTime=Tue Dec 13 20:17:21 CST 2016, time=2016-12-13, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=161184, encodeId=6884161184c8, content=哇，哎, beContent=null, objectType=article, channel=null, level=null, likeNumber=106, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://thirdwx.qlogo.cn/mmopen/vi_32/Q0j4TwGTfTKVkILniabnuT4anP3RF0Vej3wtdQkUBaoVQQnEtgRJuCA6d08SVmHylJsibr3ZOX3icakISxC61l5Aw/132, createdBy=bd3e1976218, createdName=aleale, createdTime=Thu Dec 08 12:31:17 CST 2016, time=2016-12-08, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=160879, encodeId=60e91608e989, content=非常精彩，支持支持！, beContent=null, objectType=article, channel=null, level=null, likeNumber=102, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=76491981781, createdName=1e184d7bm65(暂无匿称), createdTime=Wed Dec 07 09:47:34 CST 2016, time=2016-12-07, status=1, ipAttribution=)]
    2017-04-08 gao_jian4225

    #烹饪#

    0

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    2016-12-15 1e10c84am36(暂无匿称)

    需要全社会共同关注

    0

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    2016-12-13 卡莲

    谢谢分享学习了

    0

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    2016-12-08 aleale

    哇，哎

    0

  6. [GetPortalCommentsPageByObjectIdResponse(id=1828699, encodeId=95171828699c0, content=<a href='/topic/show?id=1b6210686b2' target=_blank style='color:#2F92EE;'>#Lancet#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=69, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=10686, encryptionId=1b6210686b2, topicName=Lancet)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=3f0227, createdName=howi, createdTime=Thu Jul 06 03:01:00 CST 2017, time=2017-07-06, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1647160, encodeId=2fd5164e16083, content=<a href='/topic/show?id=02286e2683e' target=_blank style='color:#2F92EE;'>#烹饪#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=133, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=67268, encryptionId=02286e2683e, topicName=烹饪)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=b9e923392426, createdName=gao_jian4225, createdTime=Sat Apr 08 04:01:00 CST 2017, time=2017-04-08, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=163046, encodeId=e98616304615, content=需要全社会共同关注, beContent=null, objectType=article, channel=null, level=null, likeNumber=110, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/jW482SpianMayicTRbRZ5RzdAIB7UwTkHt6fQkBP8ictliaXtc5gCUmYdAW1sAETC2nhO3q6YjRHkUibyOCtP8ibmXNObTyd63A076/0, createdBy=d4111948983, createdName=1e10c84am36(暂无匿称), createdTime=Thu Dec 15 14:36:56 CST 2016, time=2016-12-15, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=162533, encodeId=f547162533c5, content=谢谢分享学习了, beContent=null, objectType=article, channel=null, level=null, likeNumber=99, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=e4e21675717, createdName=卡莲, createdTime=Tue Dec 13 20:17:21 CST 2016, time=2016-12-13, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=161184, encodeId=6884161184c8, content=哇，哎, beContent=null, objectType=article, channel=null, level=null, likeNumber=106, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://thirdwx.qlogo.cn/mmopen/vi_32/Q0j4TwGTfTKVkILniabnuT4anP3RF0Vej3wtdQkUBaoVQQnEtgRJuCA6d08SVmHylJsibr3ZOX3icakISxC61l5Aw/132, createdBy=bd3e1976218, createdName=aleale, createdTime=Thu Dec 08 12:31:17 CST 2016, time=2016-12-08, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=160879, encodeId=60e91608e989, content=非常精彩，支持支持！, beContent=null, objectType=article, channel=null, level=null, likeNumber=102, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=76491981781, createdName=1e184d7bm65(暂无匿称), createdTime=Wed Dec 07 09:47:34 CST 2016, time=2016-12-07, status=1, ipAttribution=)]
    2016-12-07 1e184d7bm65(暂无匿称)

    非常精彩，支持支持！

    0

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