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Arthritis Res:缺乏运动及肥胖与狼疮的认知障碍有关

2017-07-25 zhuliee 来宝网

据2月15发表于Arthritis Care & Research.的文章报道,在系统性红斑狼疮女性患者中,缺乏运动和肥胖与认知功能,尤其是执行功能受损有关。



每日健康---据2月15发表于Arthritis Care & Research.的文章报道,在系统性红斑狼疮女性患者中,缺乏运动和肥胖与认知功能,尤其是执行功能受损有关。

为了评估肥胖和缺乏运动是否和女性SLE患者的认知缺损相关,来自芝加哥的加利福尼亚的Patricia Katz博士和他的同事实行了一个横断面研究,包含138例女性SLE患者,这些患者通过双能X线骨密度仪测定人体成分。

研究人员发现,有28%的女性患者缺乏运动,50%的女性患者有肥胖,20%的女性患者存在认知障碍。认知障碍由执行功能的电池评估,通过评估发现,缺乏活动的女性的认知障碍比活动的女性更常见。(23% vs. 5%, P=0.003)其中肥胖的女性患者认知障碍的比例明显高于无肥胖的女性患者(23% vs.6%),在认知测试的执行功能的部分的比例也显着高于无肥胖的女性SLE患者(19% vs.2%)。总之,女性SLE患者缺乏运动及肥胖更容易表现出认知执行功能受损。(OR值:缺乏运动 9.4,肥胖14.8)

“肥胖和缺乏活动均为认知功能损害的显着独立相关因素。”该研究的作者说:“如果队列研究结果也显示缺乏运动和肥胖是认知功能损害的预测因子,那么这两个因素可以作为我们干预的重要靶标。”

原始出处:

Patricia Katz, Laura Julian, Mary C. Tonner, et al. Physical activity, obesity, and cognitive impairment among women with systemic lupus erythematosus. Arthritis Care & Research, 2017. DOI: 10.1002/acr.21587.

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    2017-07-27 zhaojie88
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    2017-07-26 榄枷檬

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