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J Dent Res:睡觉时佩戴假牙可增加老年人患肺炎的风险

2015-05-08 MedSci MedSci原创

J Dent Res:睡觉时佩戴假牙可增加老年人患肺炎的风险越来越多人意识到不良的口腔卫生是老年人肺炎的主要危险因素。为了确定多种口腔健康相关的危险因素,我们采用了前瞻性研究以评估社区老年人群(年龄在85岁及以上)中一系列的口腔健康行为与肺炎发生率之间可能存在的关系。研究开始随机选择了524名老年人(228名男性和296名女性;平均年龄为87.8岁),检查各研究对象的口腔卫生状况,记录其口腔健康行




越来越多人意识到不良的口腔卫生是老年人肺炎的主要危险因素。为了确定多种口腔健康相关的危险因素,我们采用了前瞻性研究以评估社区老年人群(年龄在85岁及以上)中一系列的口腔健康行为与肺炎发生率之间可能存在的关系。

研究开始随机选择了524名老年人(228名男性和296名女性;平均年龄为87.8岁),检查各研究对象的口腔卫生状况,记录其口腔健康行为,评估其医疗情况,包括血液化学分析,并每年随访一次,直至其因肺炎首次住院或者因肺炎过世。

3年随访期间,出现48名相关肺炎患者(20名因肺炎死亡和28名因急性肺炎住院)。453名佩戴有义齿,186名(40.8%)患者有睡眠时佩戴义齿的习惯,其患肺炎的风险较睡眠时取下义齿的患者高(log rank P = 0.021)。多变量 Cox回归分析表明,与认知障碍 (HR为2.15;95% CI为1.06-4.34),中风史 (HR为2.46;95% CI为1.13-5.35)以及呼吸系统疾病 (HR为2.25; 95% CI为1.20-4.23)诱导的肺炎的HR相比,无论是吞咽困难还是睡眠时佩戴义齿都会使肺炎发生的危险增加约2.3倍 (对于吞咽困难来说,风险比 [HR]为2.31;95%可信区间[CI]为1.11-4.82;睡眠时佩戴义齿的HR为2.38;95% CI为1.25-4.56)。此外,与睡眠时取下义齿的患者相比,习惯睡眠时佩戴义齿的患者其舌和义齿上存在菌斑的可能性增加,牙龈发炎的可能性也会增加,白色念球菌培养阳性,血液中白细胞介素-6的水平也较高。

本研究结果表明,睡眠时佩戴义齿不仅与口腔炎症、细菌滋生相关,还会增加患肺炎的风险,因此可以说,社区口腔卫生项目对肺炎的预防会有潜在的作用。

原始出处:
Iinuma T, Arai Y, Abe Y, Takayama M, Fukumoto M, Fukui Y, Iwase T, Takebayashi T, Hirose N, Gionhaku N, Komiyama K.Denture wearing during sleep doubles the risk of pneumonia in the very elderly.J Dent Res. 2015 Mar;94(3 Suppl):28S-36S. doi: 10.1177/0022034514552493.

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  1. [GetPortalCommentsPageByObjectIdResponse(id=125092, encodeId=fea21250928d, content=好文章,还会关注, beContent=null, objectType=article, channel=null, level=null, likeNumber=86, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/jW482SpianMayicTRbRZ5RzdAIB7UwTkHt6fQkBP8ictliaXtc5gCUmYdAW1sAETC2nhO3q6YjRHkUibyOCtP8ibmXNObTyd63A076/0, createdBy=d4111948983, createdName=1e10c84am36(暂无匿称), createdTime=Tue Sep 13 11:58:00 CST 2016, time=2016-09-13, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=93518, encodeId=2f7493518ea, content=是不是可以来一篇文章, beContent=null, objectType=article, channel=null, level=null, likeNumber=115, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://cacheapi.medsci.cn/resource/upload/20151119/IMG564D22F85A3BB6344.jpg, createdBy=750e1664472, createdName=De_dzw, createdTime=Tue Jul 19 00:56:00 CST 2016, time=2016-07-19, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=49694, encodeId=b3544969464, content=注意了, beContent=null, objectType=article, channel=null, level=null, likeNumber=138, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=45101626056, createdName=忠诚向上, createdTime=Sun Dec 27 22:09:00 CST 2015, time=2015-12-27, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=23480, encodeId=dcb4234800d, content=看看, beContent=null, objectType=article, channel=null, level=null, likeNumber=97, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=ee0d1618732, createdName=huaxipanxing, createdTime=Wed May 13 21:30:00 CST 2015, time=2015-05-13, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1540667, encodeId=8cc2154066efd, content=<a href='/topic/show?id=be0ae30534b' target=_blank style='color:#2F92EE;'>#睡觉#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=79, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=73053, encryptionId=be0ae30534b, topicName=睡觉)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=cb5913283122, createdName=tsing_hit, createdTime=Sun May 10 13:12:00 CST 2015, time=2015-05-10, status=1, ipAttribution=)]
    2016-09-13 1e10c84am36(暂无匿称)

    好文章,还会关注

    0

  2. [GetPortalCommentsPageByObjectIdResponse(id=125092, encodeId=fea21250928d, content=好文章,还会关注, beContent=null, objectType=article, channel=null, level=null, likeNumber=86, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/jW482SpianMayicTRbRZ5RzdAIB7UwTkHt6fQkBP8ictliaXtc5gCUmYdAW1sAETC2nhO3q6YjRHkUibyOCtP8ibmXNObTyd63A076/0, createdBy=d4111948983, createdName=1e10c84am36(暂无匿称), createdTime=Tue Sep 13 11:58:00 CST 2016, time=2016-09-13, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=93518, encodeId=2f7493518ea, content=是不是可以来一篇文章, beContent=null, objectType=article, channel=null, level=null, likeNumber=115, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://cacheapi.medsci.cn/resource/upload/20151119/IMG564D22F85A3BB6344.jpg, createdBy=750e1664472, createdName=De_dzw, createdTime=Tue Jul 19 00:56:00 CST 2016, time=2016-07-19, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=49694, encodeId=b3544969464, content=注意了, beContent=null, objectType=article, channel=null, level=null, likeNumber=138, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=45101626056, createdName=忠诚向上, createdTime=Sun Dec 27 22:09:00 CST 2015, time=2015-12-27, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=23480, encodeId=dcb4234800d, content=看看, beContent=null, objectType=article, channel=null, level=null, likeNumber=97, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=ee0d1618732, createdName=huaxipanxing, createdTime=Wed May 13 21:30:00 CST 2015, time=2015-05-13, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1540667, encodeId=8cc2154066efd, content=<a href='/topic/show?id=be0ae30534b' target=_blank style='color:#2F92EE;'>#睡觉#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=79, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=73053, encryptionId=be0ae30534b, topicName=睡觉)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=cb5913283122, createdName=tsing_hit, createdTime=Sun May 10 13:12:00 CST 2015, time=2015-05-10, status=1, ipAttribution=)]
    2016-07-19 De_dzw

    是不是可以来一篇文章

    0

  3. [GetPortalCommentsPageByObjectIdResponse(id=125092, encodeId=fea21250928d, content=好文章,还会关注, beContent=null, objectType=article, channel=null, level=null, likeNumber=86, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/jW482SpianMayicTRbRZ5RzdAIB7UwTkHt6fQkBP8ictliaXtc5gCUmYdAW1sAETC2nhO3q6YjRHkUibyOCtP8ibmXNObTyd63A076/0, createdBy=d4111948983, createdName=1e10c84am36(暂无匿称), createdTime=Tue Sep 13 11:58:00 CST 2016, time=2016-09-13, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=93518, encodeId=2f7493518ea, content=是不是可以来一篇文章, beContent=null, objectType=article, channel=null, level=null, likeNumber=115, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://cacheapi.medsci.cn/resource/upload/20151119/IMG564D22F85A3BB6344.jpg, createdBy=750e1664472, createdName=De_dzw, createdTime=Tue Jul 19 00:56:00 CST 2016, time=2016-07-19, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=49694, encodeId=b3544969464, content=注意了, beContent=null, objectType=article, channel=null, level=null, likeNumber=138, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=45101626056, createdName=忠诚向上, createdTime=Sun Dec 27 22:09:00 CST 2015, time=2015-12-27, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=23480, encodeId=dcb4234800d, content=看看, beContent=null, objectType=article, channel=null, level=null, likeNumber=97, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=ee0d1618732, createdName=huaxipanxing, createdTime=Wed May 13 21:30:00 CST 2015, time=2015-05-13, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1540667, encodeId=8cc2154066efd, content=<a href='/topic/show?id=be0ae30534b' target=_blank style='color:#2F92EE;'>#睡觉#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=79, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=73053, encryptionId=be0ae30534b, topicName=睡觉)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=cb5913283122, createdName=tsing_hit, createdTime=Sun May 10 13:12:00 CST 2015, time=2015-05-10, status=1, ipAttribution=)]
    2015-12-27 忠诚向上

    注意了

    0

  4. [GetPortalCommentsPageByObjectIdResponse(id=125092, encodeId=fea21250928d, content=好文章,还会关注, beContent=null, objectType=article, channel=null, level=null, likeNumber=86, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/jW482SpianMayicTRbRZ5RzdAIB7UwTkHt6fQkBP8ictliaXtc5gCUmYdAW1sAETC2nhO3q6YjRHkUibyOCtP8ibmXNObTyd63A076/0, createdBy=d4111948983, createdName=1e10c84am36(暂无匿称), createdTime=Tue Sep 13 11:58:00 CST 2016, time=2016-09-13, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=93518, encodeId=2f7493518ea, content=是不是可以来一篇文章, beContent=null, objectType=article, channel=null, level=null, likeNumber=115, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://cacheapi.medsci.cn/resource/upload/20151119/IMG564D22F85A3BB6344.jpg, createdBy=750e1664472, createdName=De_dzw, createdTime=Tue Jul 19 00:56:00 CST 2016, time=2016-07-19, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=49694, encodeId=b3544969464, content=注意了, beContent=null, objectType=article, channel=null, level=null, likeNumber=138, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=45101626056, createdName=忠诚向上, createdTime=Sun Dec 27 22:09:00 CST 2015, time=2015-12-27, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=23480, encodeId=dcb4234800d, content=看看, beContent=null, objectType=article, channel=null, level=null, likeNumber=97, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=ee0d1618732, createdName=huaxipanxing, createdTime=Wed May 13 21:30:00 CST 2015, time=2015-05-13, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1540667, encodeId=8cc2154066efd, content=<a href='/topic/show?id=be0ae30534b' target=_blank style='color:#2F92EE;'>#睡觉#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=79, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=73053, encryptionId=be0ae30534b, topicName=睡觉)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=cb5913283122, createdName=tsing_hit, createdTime=Sun May 10 13:12:00 CST 2015, time=2015-05-10, status=1, ipAttribution=)]
    2015-05-13 huaxipanxing

    看看

    0

  5. [GetPortalCommentsPageByObjectIdResponse(id=125092, encodeId=fea21250928d, content=好文章,还会关注, beContent=null, objectType=article, channel=null, level=null, likeNumber=86, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/jW482SpianMayicTRbRZ5RzdAIB7UwTkHt6fQkBP8ictliaXtc5gCUmYdAW1sAETC2nhO3q6YjRHkUibyOCtP8ibmXNObTyd63A076/0, createdBy=d4111948983, createdName=1e10c84am36(暂无匿称), createdTime=Tue Sep 13 11:58:00 CST 2016, time=2016-09-13, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=93518, encodeId=2f7493518ea, content=是不是可以来一篇文章, beContent=null, objectType=article, channel=null, level=null, likeNumber=115, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://cacheapi.medsci.cn/resource/upload/20151119/IMG564D22F85A3BB6344.jpg, createdBy=750e1664472, createdName=De_dzw, createdTime=Tue Jul 19 00:56:00 CST 2016, time=2016-07-19, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=49694, encodeId=b3544969464, content=注意了, beContent=null, objectType=article, channel=null, level=null, likeNumber=138, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=45101626056, createdName=忠诚向上, createdTime=Sun Dec 27 22:09:00 CST 2015, time=2015-12-27, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=23480, encodeId=dcb4234800d, content=看看, beContent=null, objectType=article, channel=null, level=null, likeNumber=97, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=ee0d1618732, createdName=huaxipanxing, createdTime=Wed May 13 21:30:00 CST 2015, time=2015-05-13, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1540667, encodeId=8cc2154066efd, content=<a href='/topic/show?id=be0ae30534b' target=_blank style='color:#2F92EE;'>#睡觉#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=79, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=73053, encryptionId=be0ae30534b, topicName=睡觉)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=cb5913283122, createdName=tsing_hit, createdTime=Sun May 10 13:12:00 CST 2015, time=2015-05-10, status=1, ipAttribution=)]
    2015-05-10 tsing_hit

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