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PLoS One:母乳喂养可有效预防儿童龋齿的发生

2015-11-20 MedSci MedSci原创

了解母乳喂养和奶瓶喂养在儿童龋齿发展过程中发挥的作用对于帮助口腔科医生,家长以及照顾者预防儿童龋齿的发生发展来说是十分有必要的,同时对于研究人员开发有效的公共卫生政策来说也是十分有必要的。然而,对母乳喂养和奶瓶喂养对儿童龋齿的影响这一问题尚未完全理解。

了解母乳喂养和奶瓶喂养在儿童龋齿发展过程中发挥的作用对于帮助口腔科医生,家长以及照顾者预防儿童龋齿的发生发展来说是十分有必要的,同时对于研究人员开发有效的公共卫生政策来说也是十分有必要的。然而,对母乳喂养和奶瓶喂养对儿童龋齿的影响这一问题尚未完全理解。

本系统综述和meta分析旨在寻找回答这个问题的科学证据:奶瓶喂养的儿童乳牙龋齿发生率是否较母乳喂养的儿童大?为此研究人员检索了七个电子数据库的相关文献,并查阅了灰色文献。两名独立的评审员选择并提取了研究数据,并使用质量评估了偏倚的风险。采用随机效应模型进行meta分析,并用比值比(OR)和95%可信区间来评估结果。

最终共纳入了七项研究,包括五个横断面研究,一个病例对照研究和一个队列研究。横断面研究的meta分析显示,母乳喂养的儿童其龋齿率较奶瓶喂养的儿童小(OR: 0.43; 95%CI: 0.23-0.80)。四项研究表明,奶瓶喂养的儿童龋齿的数目较多(p<0.05),而三项研究发现二者之间并无此关联(p>0.05)。

因此,科学证据表明,母乳喂养可预防儿童早期龋齿的发生。据WHO/UNICEF指南推荐两岁以下的儿童接受母乳喂养存在好处。当然仍需要进一步的前瞻性观察性队列研究以证实本研究的结果。

原始出处:

Avila WM, Pordeus IA, Paiva SM, Martins CC. Breast and Bottle Feeding as Risk Factors for Dental Caries: A Systematic Review and Meta-Analysis. PLoS One. 2015 Nov 18;10(11):e0142922. doi: 10.1371/journal.pone.0142922.

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    2016-09-13 1e10c84am36(暂无匿称)

    好文章,还会关注

    0

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  3. [GetPortalCommentsPageByObjectIdResponse(id=124961, encodeId=083e1249617d, content=好文章,还会关注, beContent=null, objectType=article, channel=null, level=null, likeNumber=104, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/jW482SpianMayicTRbRZ5RzdAIB7UwTkHt6fQkBP8ictliaXtc5gCUmYdAW1sAETC2nhO3q6YjRHkUibyOCtP8ibmXNObTyd63A076/0, createdBy=d4111948983, createdName=1e10c84am36(暂无匿称), createdTime=Tue Sep 13 11:32:00 CST 2016, time=2016-09-13, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1664963, encodeId=b7c51664963e1, content=<a href='/topic/show?id=c8664008e1a' target=_blank style='color:#2F92EE;'>#喂养#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=72, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=40087, encryptionId=c8664008e1a, topicName=喂养)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=0ed425881542, createdName=ms1948154235210413, createdTime=Sat Apr 16 12:14:00 CST 2016, time=2016-04-16, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=47080, encodeId=3c8c4e08095, content=提倡母乳喂养, beContent=null, objectType=article, channel=null, level=null, likeNumber=218, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=90f31612316, createdName=xiaotaiyang1, createdTime=Tue Dec 22 17:06:00 CST 2015, time=2015-12-22, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1299500, encodeId=30a6129950006, content=<a href='/topic/show?id=7a056349485' target=_blank style='color:#2F92EE;'>#母乳#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=83, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=63494, encryptionId=7a056349485, topicName=母乳)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=bf1b289, createdName=villahu, createdTime=Sun Nov 22 13:14:00 CST 2015, time=2015-11-22, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1789736, encodeId=25af1e8973620, content=<a href='/topic/show?id=6e4814388e2' target=_blank style='color:#2F92EE;'>#Plos one#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=68, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=14388, encryptionId=6e4814388e2, topicName=Plos one)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=fda6311, createdName=119337457, createdTime=Fri Dec 11 18:14:00 CST 2015, time=2015-12-11, status=1, ipAttribution=)]
    2015-12-22 xiaotaiyang1

    提倡母乳喂养

    0

  4. [GetPortalCommentsPageByObjectIdResponse(id=124961, encodeId=083e1249617d, content=好文章,还会关注, beContent=null, objectType=article, channel=null, level=null, likeNumber=104, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/jW482SpianMayicTRbRZ5RzdAIB7UwTkHt6fQkBP8ictliaXtc5gCUmYdAW1sAETC2nhO3q6YjRHkUibyOCtP8ibmXNObTyd63A076/0, createdBy=d4111948983, createdName=1e10c84am36(暂无匿称), createdTime=Tue Sep 13 11:32:00 CST 2016, time=2016-09-13, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1664963, encodeId=b7c51664963e1, content=<a href='/topic/show?id=c8664008e1a' target=_blank style='color:#2F92EE;'>#喂养#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=72, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=40087, encryptionId=c8664008e1a, topicName=喂养)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=0ed425881542, createdName=ms1948154235210413, createdTime=Sat Apr 16 12:14:00 CST 2016, time=2016-04-16, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=47080, encodeId=3c8c4e08095, content=提倡母乳喂养, beContent=null, objectType=article, channel=null, level=null, likeNumber=218, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=90f31612316, createdName=xiaotaiyang1, createdTime=Tue Dec 22 17:06:00 CST 2015, time=2015-12-22, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1299500, encodeId=30a6129950006, content=<a href='/topic/show?id=7a056349485' target=_blank style='color:#2F92EE;'>#母乳#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=83, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=63494, encryptionId=7a056349485, topicName=母乳)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=bf1b289, createdName=villahu, createdTime=Sun Nov 22 13:14:00 CST 2015, time=2015-11-22, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1789736, encodeId=25af1e8973620, content=<a href='/topic/show?id=6e4814388e2' target=_blank style='color:#2F92EE;'>#Plos one#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=68, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=14388, encryptionId=6e4814388e2, topicName=Plos one)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=fda6311, createdName=119337457, createdTime=Fri Dec 11 18:14:00 CST 2015, time=2015-12-11, status=1, ipAttribution=)]
    2015-11-22 villahu
  5. [GetPortalCommentsPageByObjectIdResponse(id=124961, encodeId=083e1249617d, content=好文章,还会关注, beContent=null, objectType=article, channel=null, level=null, likeNumber=104, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/jW482SpianMayicTRbRZ5RzdAIB7UwTkHt6fQkBP8ictliaXtc5gCUmYdAW1sAETC2nhO3q6YjRHkUibyOCtP8ibmXNObTyd63A076/0, createdBy=d4111948983, createdName=1e10c84am36(暂无匿称), createdTime=Tue Sep 13 11:32:00 CST 2016, time=2016-09-13, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1664963, encodeId=b7c51664963e1, content=<a href='/topic/show?id=c8664008e1a' target=_blank style='color:#2F92EE;'>#喂养#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=72, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=40087, encryptionId=c8664008e1a, topicName=喂养)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=0ed425881542, createdName=ms1948154235210413, createdTime=Sat Apr 16 12:14:00 CST 2016, time=2016-04-16, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=47080, encodeId=3c8c4e08095, content=提倡母乳喂养, beContent=null, objectType=article, channel=null, level=null, likeNumber=218, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=90f31612316, createdName=xiaotaiyang1, createdTime=Tue Dec 22 17:06:00 CST 2015, time=2015-12-22, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1299500, encodeId=30a6129950006, content=<a href='/topic/show?id=7a056349485' target=_blank style='color:#2F92EE;'>#母乳#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=83, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=63494, encryptionId=7a056349485, topicName=母乳)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=bf1b289, createdName=villahu, createdTime=Sun Nov 22 13:14:00 CST 2015, time=2015-11-22, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1789736, encodeId=25af1e8973620, content=<a href='/topic/show?id=6e4814388e2' target=_blank style='color:#2F92EE;'>#Plos one#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=68, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=14388, encryptionId=6e4814388e2, topicName=Plos one)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=fda6311, createdName=119337457, createdTime=Fri Dec 11 18:14:00 CST 2015, time=2015-12-11, status=1, ipAttribution=)]

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 据统计,全球每年有大约175000名十五岁以下儿童被确诊为癌症。在发达国家中,每年的发病率增长大约0.9%,而这一结果被部分解释为诊断和报道的技术进步。儿童癌症是较少见的,并且过去数年中存活率也大为提高,这要归功于治疗技术的进步。但是,这仍旧是发达国家中儿童和青少年的首要致死因素。白血病是儿童癌症中最为常见的一种,30%的儿童癌症是白血病。儿童最为常见的两种急性白血病是急性淋巴细胞白血

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