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Phys Med Biol:用于辐射剂量评估的成人眼睛的可扩展且可变形的程式化模型

2018-03-25 cuiguizhong MedSci原创

美国佛罗里达大学生物医学工程的El Basha D近日在Phys Med Biol发表了一项工作,他们构建了一个几何眼模型,可以进行改变眼睛大小等扩展,也可允许改变眼睛形状,并且适用于眼部照射和辐射治疗的眼睛疾病研究。

美国佛罗里达大学生物医学工程的El Basha D近日在Phys Med Biol发表了一项工作,他们构建了一个几何眼模型,可以进行改变眼睛大小等扩展,也可允许改变眼睛形状,并且适用于眼部照射和辐射治疗的眼睛疾病研究。

随着眼镜片暴露于电离辐射年度限值的变化,人眼和其各种眼结构(包括晶状体、睫状体、角膜、视网膜、视神经、视网膜中央动脉和眼内结构)的预测性计算剂量学模型的建立是非常有意义的。迄今为止,大部分的计算眼模型为程式化模型、高分辨率立体像素模型和多边形网格模型。然而,它们的共同特征是,它们通常由正常大小的、大致球形的正视眼结构构成。在这项研究中,他们提出了一个几何眼模型,可以进行改变眼睛大小等扩展,也可允许改变眼睛形状,并且适用于眼部照射和辐射治疗的眼睛疾病研究。

该模型允许眼尺寸(轴向长度从20到26毫米)和眼形(从-12到+6的屈光度)连续变化。作为其用途的示范,构建了五种模型,有小尺寸的正视眼、平均尺寸的正视眼和大尺寸的正视眼以及-12D和+ 6D的平均大小的眼睛模型。通过正常单能电子束和光子束照射,给出眼睛前部和后部结构的合成能量相关剂量的系数。发现电子剂量系数随着眼后部结构变化而变化,如眼睛大小和形状;而眼睛晶状体的系数仅对眼睛大小的变化敏感。对于低于2MeV能量的光子剂量系数,没有发现眼睛大小或眼睛形状对其产生的差异。

该模型的将来可以应用到对于所有眼睛结构(不仅是晶状体)的剂量系数测量,可以作为眼睛大小和形状的一个辅助指标。

原文出处:

El Basha, D., et al., A scalable and deformable stylized model of the adult human eye for radiation dose assessment. Phys Med Biol, 2018.

本文系梅斯医学(MedSci)原创编译整理,转载需授权!

 

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    2018-04-23 sunylz
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    2018-03-31 smartxiuxiu

    有用

    0

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    2018-03-27 jiyangfei
  6. [GetPortalCommentsPageByObjectIdResponse(id=1917989, encodeId=005c191e98950, content=<a href='/topic/show?id=4f26341994' target=_blank style='color:#2F92EE;'>#Bio#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=55, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=3419, encryptionId=4f26341994, topicName=Bio)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=12de429, createdName=sunylz, createdTime=Mon Apr 23 04:51:00 CST 2018, time=2018-04-23, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1767398, encodeId=5d941e673989c, content=<a href='/topic/show?id=64f5343e2f' target=_blank style='color:#2F92EE;'>#Biol#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=59, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=3437, encryptionId=64f5343e2f, topicName=Biol)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=446937890434, createdName=12498ebem31暂无昵称, createdTime=Mon May 14 19:51:00 CST 2018, time=2018-05-14, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1687191, encodeId=6ef7168e19144, content=<a href='/topic/show?id=3b9293e37e7' target=_blank style='color:#2F92EE;'>#辐射剂量#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=64, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=93737, encryptionId=3b9293e37e7, topicName=辐射剂量)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=e22b28340090, createdName=124985dbm15(暂无昵称), createdTime=Thu Aug 02 18:51:00 CST 2018, time=2018-08-02, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=301557, encodeId=e6c230155eb8, content=有用, beContent=null, objectType=article, channel=null, level=null, likeNumber=89, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=18741984753, createdName=smartxiuxiu, createdTime=Sat Mar 31 21:28:52 CST 2018, time=2018-03-31, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1349362, encodeId=e338134936238, content=<a href='/topic/show?id=838593e35b2' target=_blank style='color:#2F92EE;'>#辐射#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=71, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=93735, encryptionId=838593e35b2, topicName=辐射)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=8e4c53, createdName=jiyangfei, createdTime=Tue Mar 27 06:51:00 CST 2018, time=2018-03-27, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1608677, encodeId=feca16086e78d, content=<a href='/topic/show?id=eb6b1145939' target=_blank style='color:#2F92EE;'>#Med#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=47, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=11459, encryptionId=eb6b1145939, topicName=Med)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=552a19396740, createdName=ms3994565386320060, createdTime=Tue Mar 27 06:51:00 CST 2018, time=2018-03-27, status=1, ipAttribution=)]
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