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Eur Respir J:急性呼吸衰竭而无创通气患者呼吸困难的患病率、危险因素和预后

2018-08-10 xing.T MedSci原创

由此可见,在因ARF而接受NIV治疗的患者中,呼吸困难较为常见且剧烈,并且其与较高的NIV失败和较差结局风险相关。

呼吸困难是插管患者较为常见而且严重的症状,但对于重症监护室(ICU)接受无创机械通气的患者发生的呼吸困难很少关注。

近日,呼吸疾病领域权威杂志Eur Respir J上发表了一篇研究文章,该研究的目的是根据对法国和比利时54个ICU中因急性呼吸衰竭(ARF)接受通气支持的患者进行前瞻性观察性队列研究的二次分析来量化因ARF接受无创通气(NIV)治疗的患者呼吸困难的患病率、强度和预后影响。研究人员通过改良的Borg量表测量呼吸困难。

在纳入的426名患者中,入院时呼吸困难评分的中位数(四分位数间)为4(3-5),在第一次NIV后为3(2-4)(p=0.001)。第一次NIV疗程后呼吸困难强度≥4与序贯器官衰竭评估评分(比值比(OR)为1.12,p=0.001)、呼吸频率(OR为1.03,p=0.032)、焦虑(OR为1.92,p=0.006)、泄漏(OR为2.5,p=0.002)和动脉二氧化碳张力(OR为0.98,p=0.025)相关。呼吸困难强度≥4与NIV失败(OR为2.41,p=0.001)以及死亡率(OR为2.11,p=0.009)独立相关,但与ICU后较高的负担和生活质量改变无关。

由此可见,在因ARF而接受NIV治疗的患者中,呼吸困难较为常见且剧烈,并且其与较高的NIV失败和较差结局风险相关。

原始出处:

Laurence Dangers,et al. Dyspnoea in patients receiving noninvasive ventilation for acute respiratory failure: prevalence, risk factors and prognostic impact. Eur Respir J. 2018. http://erj.ersjournals.com/content/52/2/1702637

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    2019-05-18 145cae3em48(暂无昵称)

    使用brog评分作为静息状态下的呼吸困难评分量表是否合适?

    0

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  5. [GetPortalCommentsPageByObjectIdResponse(id=366395, encodeId=b2ca36639562, content=使用brog评分作为静息状态下的呼吸困难评分量表是否合适?, beContent=null, objectType=article, channel=null, level=null, likeNumber=79, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=357a5088625, createdName=145cae3em48(暂无昵称), createdTime=Sat May 18 12:31:05 CST 2019, time=2019-05-18, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1250563, encodeId=76a81250563b2, content=<a href='/topic/show?id=7d6f52988e1' target=_blank style='color:#2F92EE;'>#患病率#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=72, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=52988, encryptionId=7d6f52988e1, topicName=患病率)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=f49517, createdName=xinmeili, createdTime=Sat Aug 11 15:05:00 CST 2018, time=2018-08-11, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1281866, encodeId=4f8b128186630, content=<a href='/topic/show?id=21753963364' target=_blank style='color:#2F92EE;'>#呼吸困难#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=70, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=39633, encryptionId=21753963364, topicName=呼吸困难)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=365d170, createdName=chenwq08, createdTime=Sat Aug 11 15:05:00 CST 2018, time=2018-08-11, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1495702, encodeId=be041495e022d, content=<a href='/topic/show?id=aa1e58914c2' target=_blank style='color:#2F92EE;'>#无创通气#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=106, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=58914, encryptionId=aa1e58914c2, topicName=无创通气)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=6e489186998, createdName=yhy100203, createdTime=Sat Aug 11 15:05:00 CST 2018, time=2018-08-11, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1582522, encodeId=1b5715825221a, content=<a href='/topic/show?id=d6be52242ec' target=_blank style='color:#2F92EE;'>#急性呼吸衰竭#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=69, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=52242, encryptionId=d6be52242ec, topicName=急性呼吸衰竭)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=be9016942559, createdName=12498dabm82暂无昵称, createdTime=Sat Aug 11 15:05:00 CST 2018, time=2018-08-11, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=337621, encodeId=99f433e621fb, content=学习了,谢谢分享~~~~, beContent=null, objectType=article, channel=null, level=null, likeNumber=89, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=d7e71713450, createdName=太阳系小猪, createdTime=Fri Aug 10 06:42:48 CST 2018, time=2018-08-10, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=337614, encodeId=6cff33e6148a, content=学习学习学习, beContent=null, objectType=article, channel=null, level=null, likeNumber=98, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/mStl88fu4NfNLvzZhgPxRkia1DP5MpwEgtXo1XhXA11xD6MWKxunAZFXKSNic0fWHUQx83oNHPlRMxxIctM83QKeCLkJpMibibiaC/0, createdBy=7e581734408, createdName=深海的鱼, createdTime=Fri Aug 10 06:39:31 CST 2018, time=2018-08-10, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=337603, encodeId=370a33e6034d, content=好文,值得点赞!认真学习,应用于实践!谢谢分享给广大同好!, beContent=null, objectType=article, channel=null, level=null, likeNumber=99, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=30251637888, createdName=lietome15, createdTime=Fri Aug 10 06:18:02 CST 2018, time=2018-08-10, status=1, ipAttribution=)]
  6. [GetPortalCommentsPageByObjectIdResponse(id=366395, encodeId=b2ca36639562, content=使用brog评分作为静息状态下的呼吸困难评分量表是否合适?, beContent=null, objectType=article, channel=null, level=null, likeNumber=79, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=357a5088625, createdName=145cae3em48(暂无昵称), createdTime=Sat May 18 12:31:05 CST 2019, time=2019-05-18, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1250563, encodeId=76a81250563b2, content=<a href='/topic/show?id=7d6f52988e1' target=_blank style='color:#2F92EE;'>#患病率#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=72, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=52988, encryptionId=7d6f52988e1, topicName=患病率)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=f49517, createdName=xinmeili, createdTime=Sat Aug 11 15:05:00 CST 2018, time=2018-08-11, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1281866, encodeId=4f8b128186630, content=<a href='/topic/show?id=21753963364' target=_blank style='color:#2F92EE;'>#呼吸困难#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=70, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=39633, encryptionId=21753963364, topicName=呼吸困难)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=365d170, createdName=chenwq08, createdTime=Sat Aug 11 15:05:00 CST 2018, time=2018-08-11, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1495702, encodeId=be041495e022d, content=<a href='/topic/show?id=aa1e58914c2' target=_blank style='color:#2F92EE;'>#无创通气#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=106, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=58914, encryptionId=aa1e58914c2, topicName=无创通气)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=6e489186998, createdName=yhy100203, createdTime=Sat Aug 11 15:05:00 CST 2018, time=2018-08-11, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1582522, encodeId=1b5715825221a, content=<a href='/topic/show?id=d6be52242ec' target=_blank style='color:#2F92EE;'>#急性呼吸衰竭#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=69, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=52242, encryptionId=d6be52242ec, topicName=急性呼吸衰竭)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=be9016942559, createdName=12498dabm82暂无昵称, createdTime=Sat Aug 11 15:05:00 CST 2018, time=2018-08-11, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=337621, encodeId=99f433e621fb, content=学习了,谢谢分享~~~~, beContent=null, objectType=article, channel=null, level=null, likeNumber=89, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=d7e71713450, createdName=太阳系小猪, createdTime=Fri Aug 10 06:42:48 CST 2018, time=2018-08-10, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=337614, encodeId=6cff33e6148a, content=学习学习学习, beContent=null, objectType=article, channel=null, level=null, likeNumber=98, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/mStl88fu4NfNLvzZhgPxRkia1DP5MpwEgtXo1XhXA11xD6MWKxunAZFXKSNic0fWHUQx83oNHPlRMxxIctM83QKeCLkJpMibibiaC/0, createdBy=7e581734408, createdName=深海的鱼, createdTime=Fri Aug 10 06:39:31 CST 2018, time=2018-08-10, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=337603, encodeId=370a33e6034d, content=好文,值得点赞!认真学习,应用于实践!谢谢分享给广大同好!, beContent=null, objectType=article, channel=null, level=null, likeNumber=99, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=30251637888, createdName=lietome15, createdTime=Fri Aug 10 06:18:02 CST 2018, time=2018-08-10, status=1, ipAttribution=)]
    2018-08-10 太阳系小猪

    学习了,谢谢分享~~~~

    0

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    2018-08-10 深海的鱼

    学习学习学习

    0

  8. [GetPortalCommentsPageByObjectIdResponse(id=366395, encodeId=b2ca36639562, content=使用brog评分作为静息状态下的呼吸困难评分量表是否合适?, beContent=null, objectType=article, channel=null, level=null, likeNumber=79, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=357a5088625, createdName=145cae3em48(暂无昵称), createdTime=Sat May 18 12:31:05 CST 2019, time=2019-05-18, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1250563, encodeId=76a81250563b2, content=<a href='/topic/show?id=7d6f52988e1' target=_blank style='color:#2F92EE;'>#患病率#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=72, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=52988, encryptionId=7d6f52988e1, topicName=患病率)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=f49517, createdName=xinmeili, createdTime=Sat Aug 11 15:05:00 CST 2018, time=2018-08-11, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1281866, encodeId=4f8b128186630, content=<a href='/topic/show?id=21753963364' target=_blank style='color:#2F92EE;'>#呼吸困难#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=70, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=39633, encryptionId=21753963364, topicName=呼吸困难)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=365d170, createdName=chenwq08, createdTime=Sat Aug 11 15:05:00 CST 2018, time=2018-08-11, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1495702, encodeId=be041495e022d, content=<a href='/topic/show?id=aa1e58914c2' target=_blank style='color:#2F92EE;'>#无创通气#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=106, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=58914, encryptionId=aa1e58914c2, topicName=无创通气)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=6e489186998, createdName=yhy100203, createdTime=Sat Aug 11 15:05:00 CST 2018, time=2018-08-11, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1582522, encodeId=1b5715825221a, content=<a href='/topic/show?id=d6be52242ec' target=_blank style='color:#2F92EE;'>#急性呼吸衰竭#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=69, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=52242, encryptionId=d6be52242ec, topicName=急性呼吸衰竭)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=be9016942559, createdName=12498dabm82暂无昵称, createdTime=Sat Aug 11 15:05:00 CST 2018, time=2018-08-11, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=337621, encodeId=99f433e621fb, content=学习了,谢谢分享~~~~, beContent=null, objectType=article, channel=null, level=null, likeNumber=89, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=d7e71713450, createdName=太阳系小猪, createdTime=Fri Aug 10 06:42:48 CST 2018, time=2018-08-10, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=337614, encodeId=6cff33e6148a, content=学习学习学习, beContent=null, objectType=article, channel=null, level=null, likeNumber=98, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/mStl88fu4NfNLvzZhgPxRkia1DP5MpwEgtXo1XhXA11xD6MWKxunAZFXKSNic0fWHUQx83oNHPlRMxxIctM83QKeCLkJpMibibiaC/0, createdBy=7e581734408, createdName=深海的鱼, createdTime=Fri Aug 10 06:39:31 CST 2018, time=2018-08-10, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=337603, encodeId=370a33e6034d, content=好文,值得点赞!认真学习,应用于实践!谢谢分享给广大同好!, beContent=null, objectType=article, channel=null, level=null, likeNumber=99, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=30251637888, createdName=lietome15, createdTime=Fri Aug 10 06:18:02 CST 2018, time=2018-08-10, status=1, ipAttribution=)]
    2018-08-10 lietome15

    好文,值得点赞!认真学习,应用于实践!谢谢分享给广大同好!

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