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J Diabetes&Metabolism:反转!富含碳水化合物的植物性饮食或可改善Ⅰ型糖尿病

2020-07-28 Cathy 转化医学网

导言:Ⅰ型糖尿病是一种慢性自身免疫性疾病,其特征是胰岛β细胞被破坏、胰岛素分泌绝对不足而导致高血糖。虽然我国Ⅰ型糖尿病发病率较低,但相比于Ⅱ型糖尿病,Ⅰ型糖尿病往往较重,更不容易控制。而近期

导言:Ⅰ型糖尿病是一种慢性自身免疫性疾病,其特征是胰岛β细胞被破坏、胰岛素分泌绝对不足而导致高血糖。虽然我国Ⅰ型糖尿病发病率较低,但相比于Ⅱ型糖尿病,Ⅰ型糖尿病往往较重,更不容易控制。而近期有研究发现,富含碳水化合物的植物性饮食或可改善Ⅰ型糖尿病。

碳水化合物,即糖类化合物。为了控制血糖,Ⅰ型糖尿病患者的饮食指南通常提示需要谨慎摄入碳水化合物。而近期有一项研究表明,富含碳水化合物的植物性饮食可以改善Ⅰ型糖尿病患者的胰岛素敏感性和其他健康指标,并改善了整体健康状况。

该研究由美国责任医师协会的研究人员发表在《糖尿病与代谢杂志》上。题为“Plant-Based Diets for Type 1 Diabetes”。

该研究分析了两例Ⅰ型糖尿病患者的饮食案例。两位患者都采用了富含全碳水化合物的植物性饮食,包括水果,蔬菜,全谷物和豆类。患者的健康护理团队在饮食改变前后跟踪他们的血糖控制、心脏病风险因素以及其他健康指标。

其中一项案例研究追踪了一名女性患者,该女性于2018年被诊断出患有Ⅰ型糖尿病。当时,她的A1c(衡量三个月血糖水平的指标)为8.7%。她最初采用低碳水化合物(每天少于30克碳水化合物),高脂肪饮食,其中肉和奶制品含量很高。她的血糖稳定了,但是每克碳水化合物的摄入需要消耗更多的胰岛素,她的总胆固醇也从175mg / dL增加到221mg / dL。在2019年1月,她改吃植物性饮食,淘汰了乳制品,鸡蛋和肉类。结果该患者减少了胰岛素剂量,并将A1c水平维持在5.4%,胆固醇水平降至158 mg / dL。

该研究的作者,内科医生委员会临床研究主任Hana Kahleova博士说:“这项研究挑战了碳水化合物是糖尿病患者的敌人的错误观念,在本案例研究中,病人的情况正好相反:在饮食中添加更多有益健康的碳水化合物,减少了她的胰岛素需求,并改善了整体健康状况。”

另一个案例是一名42岁的男性,他在25岁时被诊断出患有Ⅰ型糖尿病,他从饮食中淘汰了动物性食品,转而以植物性饮食为基础。他每天摄入的碳水化合物从150克增加到400-450克。在采用富含碳水化合物的植物性饮食之后,他的体重减轻了,胰岛素需求也减少了,并且他的A1c从6.2%降低到5.5-5.8%。

作者指出,先前的一项小规模研究支持了该案例研究的结果,研究人员发现高碳水化合物,高纤维饮食可以改善10位Ⅰ型糖尿病患者的血糖控制。下一步,作者建议需要进行随机临床试验,以验证案例研究的结果,评估其可推广性,并量化植物性饮食在治疗Ⅰ型糖尿病中的有效性。

先前的研究发现,低脂植物性饮食对2型糖尿病患者有益。研究还表明,与非素食者相比,那些食用植物性饮食的人罹患2型糖尿病的风险降低了约一半。

Kahleova博士补充说:“数十年的研究证明,植物性饮食对2型糖尿病患者有益。现在,这些突破性的案例研究为Ⅰ型糖尿病患者带来了希望。”

原始出处:

Hana Kahleova, Brian Carlsen, Rickisha Berrien Lopez, et.al. Plant-Based Diets for Type 1 Diabetes. Journal of Diabetes and Metabolism

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createdBy=24ef12409748, createdName=lingaifan, createdTime=Thu Jul 30 04:35:43 CST 2020, time=2020-07-30, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1577231, encodeId=b55c15e72314c, content=<a href='/topic/show?id=d86d1159e36' target=_blank style='color:#2F92EE;'>#Metabolism#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=82, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=11597, encryptionId=d86d1159e36, topicName=Metabolism)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=1a6516392333, createdName=1249859em43(暂无昵称), createdTime=Thu Jul 30 04:35:43 CST 2020, time=2020-07-30, status=1, ipAttribution=)]
    2021-05-06 xuyong535
  4. [GetPortalCommentsPageByObjectIdResponse(id=1639551, encodeId=528b16395516b, content=<a href='/topic/show?id=afda591646' target=_blank style='color:#2F92EE;'>#DIA#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=54, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=5916, encryptionId=afda591646, topicName=DIA)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=987022654425, createdName=ms9608593228839890, createdTime=Thu Feb 04 06:35:43 CST 2021, time=2021-02-04, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1906442, encodeId=2d981906442d0, content=<a href='/topic/show?id=7795334e220' target=_blank style='color:#2F92EE;'>#化合物#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=72, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=33472, encryptionId=7795334e220, topicName=化合物)], attachment=null, authenticateStatus=null, createdAvatar=, 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GetPortalCommentsPageByObjectIdResponse(id=1464388, encodeId=205514643880e, content=<a href='/topic/show?id=9b04641580e' target=_blank style='color:#2F92EE;'>#水化#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=85, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=64158, encryptionId=9b04641580e, topicName=水化)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=f1276671681, createdName=yuanming9, createdTime=Thu Jul 30 04:35:43 CST 2020, time=2020-07-30, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1533281, encodeId=70cf153328135, content=<a href='/topic/show?id=5aa662e4339' target=_blank style='color:#2F92EE;'>#植物性饮食#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=121, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=62743, encryptionId=5aa662e4339, topicName=植物性饮食)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=24ef12409748, createdName=lingaifan, createdTime=Thu Jul 30 04:35:43 CST 2020, time=2020-07-30, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1577231, encodeId=b55c15e72314c, content=<a href='/topic/show?id=d86d1159e36' target=_blank style='color:#2F92EE;'>#Metabolism#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=82, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=11597, encryptionId=d86d1159e36, topicName=Metabolism)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=1a6516392333, createdName=1249859em43(暂无昵称), createdTime=Thu Jul 30 04:35:43 CST 2020, time=2020-07-30, status=1, ipAttribution=)]
  5. 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style='color:#2F92EE;'>#Diabetes#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=64, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=5917, encryptionId=c097591ed5, topicName=Diabetes)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=0045169, createdName=木头人513, createdTime=Sat Nov 28 02:35:43 CST 2020, time=2020-11-28, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1896707, encodeId=4fe41896e0723, content=<a href='/topic/show?id=4a391158248' target=_blank style='color:#2F92EE;'>#MET#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=91, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=11582, encryptionId=4a391158248, topicName=MET)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=18fc139, createdName=一闲, createdTime=Sun Nov 22 17:35:43 CST 2020, time=2020-11-22, status=1, ipAttribution=), 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createdBy=24ef12409748, createdName=lingaifan, createdTime=Thu Jul 30 04:35:43 CST 2020, time=2020-07-30, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1577231, encodeId=b55c15e72314c, content=<a href='/topic/show?id=d86d1159e36' target=_blank style='color:#2F92EE;'>#Metabolism#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=82, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=11597, encryptionId=d86d1159e36, topicName=Metabolism)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=1a6516392333, createdName=1249859em43(暂无昵称), createdTime=Thu Jul 30 04:35:43 CST 2020, time=2020-07-30, status=1, ipAttribution=)]
    2021-06-12 guojianrong
  6. [GetPortalCommentsPageByObjectIdResponse(id=1639551, encodeId=528b16395516b, content=<a href='/topic/show?id=afda591646' target=_blank style='color:#2F92EE;'>#DIA#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=54, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=5916, encryptionId=afda591646, topicName=DIA)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=987022654425, createdName=ms9608593228839890, createdTime=Thu Feb 04 06:35:43 CST 2021, time=2021-02-04, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1906442, encodeId=2d981906442d0, content=<a href='/topic/show?id=7795334e220' target=_blank style='color:#2F92EE;'>#化合物#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=72, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=33472, encryptionId=7795334e220, topicName=化合物)], attachment=null, authenticateStatus=null, createdAvatar=, 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createdBy=24ef12409748, createdName=lingaifan, createdTime=Thu Jul 30 04:35:43 CST 2020, time=2020-07-30, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1577231, encodeId=b55c15e72314c, content=<a href='/topic/show?id=d86d1159e36' target=_blank style='color:#2F92EE;'>#Metabolism#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=82, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=11597, encryptionId=d86d1159e36, topicName=Metabolism)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=1a6516392333, createdName=1249859em43(暂无昵称), createdTime=Thu Jul 30 04:35:43 CST 2020, time=2020-07-30, status=1, ipAttribution=)]
  7. [GetPortalCommentsPageByObjectIdResponse(id=1639551, encodeId=528b16395516b, content=<a href='/topic/show?id=afda591646' target=_blank style='color:#2F92EE;'>#DIA#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=54, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=5916, encryptionId=afda591646, topicName=DIA)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=987022654425, createdName=ms9608593228839890, createdTime=Thu Feb 04 06:35:43 CST 2021, time=2021-02-04, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1906442, encodeId=2d981906442d0, content=<a href='/topic/show?id=7795334e220' target=_blank style='color:#2F92EE;'>#化合物#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=72, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=33472, encryptionId=7795334e220, topicName=化合物)], attachment=null, authenticateStatus=null, createdAvatar=, 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topicList=[TopicDto(id=3352, encryptionId=9bea33520d, topicName=BET)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=9a1a37427546, createdName=ms5439512287675881, createdTime=Sat Feb 13 14:35:43 CST 2021, time=2021-02-13, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1888180, encodeId=da5018881803e, content=<a href='/topic/show?id=d56611584ec' target=_blank style='color:#2F92EE;'>#Meta#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=71, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=11584, encryptionId=d56611584ec, topicName=Meta)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=d8f4110, createdName=guojianrong, createdTime=Sat Jun 12 23:35:43 CST 2021, time=2021-06-12, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1902470, encodeId=e90319024e092, content=<a href='/topic/show?id=c097591ed5' target=_blank style='color:#2F92EE;'>#Diabetes#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=64, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=5917, encryptionId=c097591ed5, topicName=Diabetes)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=0045169, createdName=木头人513, createdTime=Sat Nov 28 02:35:43 CST 2020, time=2020-11-28, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1896707, encodeId=4fe41896e0723, content=<a href='/topic/show?id=4a391158248' target=_blank style='color:#2F92EE;'>#MET#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=91, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=11582, encryptionId=4a391158248, topicName=MET)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=18fc139, createdName=一闲, createdTime=Sun Nov 22 17:35:43 CST 2020, time=2020-11-22, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1464388, encodeId=205514643880e, content=<a href='/topic/show?id=9b04641580e' target=_blank style='color:#2F92EE;'>#水化#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=85, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=64158, encryptionId=9b04641580e, topicName=水化)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=f1276671681, createdName=yuanming9, createdTime=Thu Jul 30 04:35:43 CST 2020, time=2020-07-30, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1533281, encodeId=70cf153328135, content=<a href='/topic/show?id=5aa662e4339' target=_blank style='color:#2F92EE;'>#植物性饮食#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=121, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=62743, encryptionId=5aa662e4339, topicName=植物性饮食)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=24ef12409748, createdName=lingaifan, createdTime=Thu Jul 30 04:35:43 CST 2020, time=2020-07-30, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1577231, encodeId=b55c15e72314c, content=<a href='/topic/show?id=d86d1159e36' target=_blank style='color:#2F92EE;'>#Metabolism#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=82, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=11597, encryptionId=d86d1159e36, topicName=Metabolism)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=1a6516392333, createdName=1249859em43(暂无昵称), createdTime=Thu Jul 30 04:35:43 CST 2020, time=2020-07-30, status=1, ipAttribution=)]
    2020-11-22 一闲
  8. [GetPortalCommentsPageByObjectIdResponse(id=1639551, encodeId=528b16395516b, content=<a href='/topic/show?id=afda591646' target=_blank style='color:#2F92EE;'>#DIA#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=54, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=5916, encryptionId=afda591646, topicName=DIA)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=987022654425, createdName=ms9608593228839890, createdTime=Thu Feb 04 06:35:43 CST 2021, time=2021-02-04, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1906442, encodeId=2d981906442d0, content=<a href='/topic/show?id=7795334e220' target=_blank style='color:#2F92EE;'>#化合物#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=72, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=33472, encryptionId=7795334e220, topicName=化合物)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=267e204, createdName=wangyang7958, createdTime=Tue Jun 15 20:35:43 CST 2021, time=2021-06-15, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1745353, encodeId=07531e4535304, content=<a href='/topic/show?id=bdc262694bb' target=_blank style='color:#2F92EE;'>#植物#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=98, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=62694, encryptionId=bdc262694bb, topicName=植物)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=6a5e35527958, createdName=xuyong535, createdTime=Thu May 06 10:35:43 CST 2021, time=2021-05-06, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1761471, encodeId=f2511e614712d, content=<a href='/topic/show?id=9bea33520d' target=_blank style='color:#2F92EE;'>#BET#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=64, replyNumber=0, topicName=null, topicId=null, 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style='color:#2F92EE;'>#Diabetes#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=64, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=5917, encryptionId=c097591ed5, topicName=Diabetes)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=0045169, createdName=木头人513, createdTime=Sat Nov 28 02:35:43 CST 2020, time=2020-11-28, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1896707, encodeId=4fe41896e0723, content=<a href='/topic/show?id=4a391158248' target=_blank style='color:#2F92EE;'>#MET#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=91, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=11582, encryptionId=4a391158248, topicName=MET)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=18fc139, createdName=一闲, createdTime=Sun Nov 22 17:35:43 CST 2020, time=2020-11-22, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1464388, encodeId=205514643880e, content=<a href='/topic/show?id=9b04641580e' target=_blank style='color:#2F92EE;'>#水化#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=85, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=64158, encryptionId=9b04641580e, topicName=水化)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=f1276671681, createdName=yuanming9, createdTime=Thu Jul 30 04:35:43 CST 2020, time=2020-07-30, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1533281, encodeId=70cf153328135, content=<a href='/topic/show?id=5aa662e4339' target=_blank style='color:#2F92EE;'>#植物性饮食#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=121, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=62743, encryptionId=5aa662e4339, topicName=植物性饮食)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=24ef12409748, createdName=lingaifan, createdTime=Thu Jul 30 04:35:43 CST 2020, time=2020-07-30, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1577231, encodeId=b55c15e72314c, content=<a href='/topic/show?id=d86d1159e36' target=_blank style='color:#2F92EE;'>#Metabolism#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=82, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=11597, encryptionId=d86d1159e36, topicName=Metabolism)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=1a6516392333, createdName=1249859em43(暂无昵称), createdTime=Thu Jul 30 04:35:43 CST 2020, time=2020-07-30, status=1, ipAttribution=)]
    2020-07-30 yuanming9
  9. [GetPortalCommentsPageByObjectIdResponse(id=1639551, encodeId=528b16395516b, content=<a href='/topic/show?id=afda591646' target=_blank style='color:#2F92EE;'>#DIA#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=54, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=5916, encryptionId=afda591646, topicName=DIA)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=987022654425, createdName=ms9608593228839890, createdTime=Thu Feb 04 06:35:43 CST 2021, time=2021-02-04, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1906442, encodeId=2d981906442d0, content=<a href='/topic/show?id=7795334e220' target=_blank style='color:#2F92EE;'>#化合物#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=72, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=33472, encryptionId=7795334e220, topicName=化合物)], attachment=null, authenticateStatus=null, createdAvatar=, 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style='color:#2F92EE;'>#Diabetes#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=64, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=5917, encryptionId=c097591ed5, topicName=Diabetes)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=0045169, createdName=木头人513, createdTime=Sat Nov 28 02:35:43 CST 2020, time=2020-11-28, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1896707, encodeId=4fe41896e0723, content=<a href='/topic/show?id=4a391158248' target=_blank style='color:#2F92EE;'>#MET#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=91, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=11582, encryptionId=4a391158248, topicName=MET)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=18fc139, createdName=一闲, createdTime=Sun Nov 22 17:35:43 CST 2020, time=2020-11-22, status=1, ipAttribution=), 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createdBy=24ef12409748, createdName=lingaifan, createdTime=Thu Jul 30 04:35:43 CST 2020, time=2020-07-30, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1577231, encodeId=b55c15e72314c, content=<a href='/topic/show?id=d86d1159e36' target=_blank style='color:#2F92EE;'>#Metabolism#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=82, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=11597, encryptionId=d86d1159e36, topicName=Metabolism)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=1a6516392333, createdName=1249859em43(暂无昵称), createdTime=Thu Jul 30 04:35:43 CST 2020, time=2020-07-30, status=1, ipAttribution=)]
  10. [GetPortalCommentsPageByObjectIdResponse(id=1639551, encodeId=528b16395516b, content=<a href='/topic/show?id=afda591646' target=_blank style='color:#2F92EE;'>#DIA#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=54, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=5916, encryptionId=afda591646, topicName=DIA)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=987022654425, createdName=ms9608593228839890, createdTime=Thu Feb 04 06:35:43 CST 2021, time=2021-02-04, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1906442, encodeId=2d981906442d0, content=<a href='/topic/show?id=7795334e220' target=_blank style='color:#2F92EE;'>#化合物#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=72, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=33472, encryptionId=7795334e220, topicName=化合物)], attachment=null, authenticateStatus=null, createdAvatar=, 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