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JACC:任何可检测的超敏肌钙蛋白水平都与胸痛患者不良预后相关

2017-10-24 MedSci MedSci原创

目前,对于超敏肌钙蛋白(hs-cTn)水平和胸痛但不伴有心梗患者结局的临床研究鲜有报道。本研究提出一个假设:任何可检测到的高水平hs-cTn均与患者的不良结局预后有关。本研究纳入了2011年至2014年22589名胸痛且大于25岁并检测了hs-cTn水平的患者,将出现有可能影响hs-cTn水平的急性情况患者、心梗患者或缺乏能保证hs-cTn水平稳定信息的患者被排除在外,主要观察的事件为全因死亡率、

目前,对于超敏肌钙蛋白(hs-cTn)水平和胸痛但不伴有心梗患者结局的临床研究鲜有报道。本研究提出一个假设:任何可检测到的高水平hs-cTn均与患者的不良结局预后有关。本研究纳入了2011年至2014年22589名胸痛且大于25岁并检测了hs-cTn水平的患者,将出现有可能影响hs-cTn水平的急性情况患者、心梗患者或缺乏能保证hs-cTn水平稳定信息的患者被排除在外,主要观察的事件为全因死亡率、心源性死亡率、非心源性死亡率、心梗和心衰。最终共纳入19460名患者,平均年龄为54 ± 17岁,经过平均3.3 ± 1.2年时间的随访,1349(6.9%)名患者死亡。在hs-cTn水平为5 - 9, 10 - 14, 15 - 29, 30 - 49和 ≥50 ng/l的患者的全因死亡率的HR(95% Cl)分别为2.00 (1.66 - 2.42), 2.92 (2.38 - 3.59), 4.07 (3.28 - 5.05), 6.77 (5.22 - 8.78)和 9.68 (7.18 - 13.00)。与hs-cTn <5 ng/l的患者相比,任何可检测到的hs-cTn水平与

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    2017-11-04 hbwxf
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    2017-11-05 1e145228m78(暂无匿称)

    学习了谢谢作者分享!学习了谢谢作者分享!

    0

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    2017-11-04 海之蓝

    学习

    0

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    2017-10-25 明天会更好!

    谢谢分享谢谢分享

    0

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    2017-10-24 Jackie Li

    学习

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