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Endocrinology:针灸有利于减轻焦虑和抑郁情绪

2015-07-26 MedSci MedSci原创

来自乔治城大学医学中心(GUMC)的研究人员表示,进行动物研究为中国探究慢性病治疗机制提供了强有力的证据。Ladan Eshkevari博士(GUMC护理系、药理学和生理学副教授、麻醉护士、注册针灸师)说:“针灸的好处是众所周知的,且是有证据基础的。这项研究的重点在于演示针灸是如何作用于机体,并使得接受治疗的患者减轻压力和疼痛、解除抑郁情绪的。现在我们已经发现了针灸潜在的作用机制,但是我们需要采用

来自乔治城大学医学中心(GUMC)的研究人员表示,进行动物研究为中国探究慢性病治疗机制提供了强有力的证据。


Ladan Eshkevari博士(GUMC护理系、药理学和生理学副教授、麻醉护士、注册针灸师)说:“针灸的好处是众所周知的,且是有证据基础的。这项研究的重点在于演示针灸是如何作用于机体,并使得接受治疗的患者减轻压力和疼痛、解除抑郁情绪的。现在我们已经发现了针灸潜在的作用机制,但是我们需要采用盲法、安慰剂对照的临床试验以获得确切结论。

Eshkevari和她的团队采用电针刺一个功能强大的穴位——足三里 (St36),她们发现,这种作用于下丘脑-垂体-肾上腺轴(HPA)的钝性刺激会影响机体的慢性疼痛体验、免疫系统、情绪和情感等因素。针灸通过影响HPA轴进而减少相关激素的分泌,一些抗抑郁药和抗焦虑药的作用机制也是如此。

研究人员已经证明,对于因感冒引起慢性疼痛的小鼠,采用针灸治疗可以抑制HPA激素分泌,进而减轻小鼠疼痛,且这种作用效果是持久的。

试验分为四组进行:一组小鼠采用针灸方式(经电针以保证电刺激均匀分配);一组小鼠采用假针灸的方式(电刺激不在穴位);安慰剂组不给予任何针灸治疗;对照组既无压力源也无针灸治疗。研究人员采用两种试验方式:第一种方式是小鼠接受规律的针灸治疗,而另一种方式是在小鼠存在压力源时进行针灸治疗。目的是探究哪种针灸方式在临床更常用。

试验证明,小鼠接受慢性冷刺激数分钟后针刺足三里同压力源出现前预防性针刺足三里穴一样有效,都可减少应激激素的升高。且该试验采用一种药物作用于HPA轴以减少激素的分泌,事实证明,该药物具有同针灸相同的效果,这也间接证明了针灸的作用十分有效。

Eshkevari博士说道:“这是第一篇将存在焦虑和抑郁表现的小鼠同针刺足三里联系起来的文章,试验结果表明,针刺足三里可以有效抑制应激激素的释放,并减少小鼠的焦虑和抑郁行为,这项研究具有十分广阔的未来,它预示着针灸的应用前景十分广阔。”

不过,MedSci也提醒,这仅仅是动物研究,在人类是否也具有相似的效果,还需要进一步研究。另外,在传统针灸中,足三里,并不是主治焦虑,抑郁这一类疾病。

原始出处:
Eshkevari L, Mulroney SE, Egan R, Lao L.Effects of Acupuncture, RU-486 on the Hypothalamic-Pituitary-Adrenal Axis in Chronically Stressed Adult Male Rats. Endocrinology. 2015 Jul 21:EN20151018
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    2015-08-14 jdklsj

    中医的伟大!!

    0

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    2015-07-28 lyrichen

    感觉什么病都行,什么病都不行

    0

  5. [GetPortalCommentsPageByObjectIdResponse(id=1785199, encodeId=d5071e851998a, content=<a href='/topic/show?id=4c2a6e614a' target=_blank style='color:#2F92EE;'>#Endocrinology#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=67, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=6761, encryptionId=4c2a6e614a, topicName=Endocrinology)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=48732500158, createdName=12498c32m68暂无昵称, createdTime=Mon Jul 27 16:47:00 CST 2015, time=2015-07-27, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=35560, encodeId=f5153556070, content=中医的伟大!!, beContent=null, objectType=article, channel=null, level=null, likeNumber=126, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=10a41638418, createdName=jdklsj, createdTime=Fri Aug 14 13:17:00 CST 2015, time=2015-08-14, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=2023816, encodeId=6a412023816db, content=<a href='/topic/show?id=8bc8549e0d2' target=_blank style='color:#2F92EE;'>#抑郁情绪#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=71, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=54970, encryptionId=8bc8549e0d2, topicName=抑郁情绪)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=c49e75, createdName=qjddjq, createdTime=Tue Aug 11 23:47:00 CST 2015, time=2015-08-11, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=33630, encodeId=1c9b336309c, content=感觉什么病都行,什么病都不行, beContent=null, objectType=article, channel=null, level=null, likeNumber=131, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=a7311615220, createdName=lyrichen, createdTime=Tue Jul 28 08:17:00 CST 2015, time=2015-07-28, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=33552, encodeId=f98e3355226, content=评论都极到位, beContent=null, objectType=article, channel=null, level=null, likeNumber=160, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/mONcle9pic3yz0JbjHQ7nicJU7lHMOu0Itf3Zv3VBzEvK3k4AFPBXhiaxIRNGVI33GicoRXQEjkaasjdlWKwZuwcyhDP9Jibqt5ct/0, createdBy=f1281613275, createdName=zhouanxiu, createdTime=Mon Jul 27 06:38:00 CST 2015, time=2015-07-27, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=33540, encodeId=72b733540e0, content=针灸在刺法上有严格的要求,但传到国外就演变成了单纯的电刺激,不知是否对疗效有影响。, beContent=null, objectType=article, channel=null, level=null, likeNumber=149, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://cacheapi.medsci.cn/resource/upload/20150721/IMG55AE501E5DCEC7711.jpg, createdBy=34aa1635032, createdName=KR0817, createdTime=Sun Jul 26 22:40:00 CST 2015, time=2015-07-26, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=33523, encodeId=6da4335237e, content=足三里这个穴位在治疗慢性肾脏病也有帮助,13年发的文章显示, beContent=null, objectType=article, channel=null, level=null, likeNumber=139, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/mONcle9pic3ykRSkuxjt93yc9tvDWfIQItrwiaKSCps5kyrTyDlwic2FgoCWe88wR3ZiaggKYGueDIp26zVgnbzriaQ/0, createdBy=89d71602869, createdName=sundong, createdTime=Sun Jul 26 19:26:00 CST 2015, time=2015-07-26, status=1, ipAttribution=)]
    2015-07-27 zhouanxiu

    评论都极到位

    0

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    2015-07-26 KR0817

    针灸在刺法上有严格的要求,但传到国外就演变成了单纯的电刺激,不知是否对疗效有影响。

    0

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    2015-07-26 sundong

    足三里这个穴位在治疗慢性肾脏病也有帮助,13年发的文章显示

    0

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