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BMJ Open:“维生素D缺乏导致代谢疾病风险增加”再一次得到证实

2015-12-06 Mechront 译 MedSci原创

维生素D缺乏是一个普遍存在的健康问题,越来越多的研究表明,缺乏维生素D会导致各种慢性疾病风险增加,不过对于少数群体,维生素D缺乏是否也会导致代谢性疾病风险增加呢?研究者对居住在南韩的健康北韩难民进行了一项研究,对纵向队列进行横断面分析。该研究共纳入了386名年龄≥30岁的北韩难民,检测去25(OH)D水平。研究数据显示参与者中87%的表现出齐刷刷D缺乏 (25(OH)D <20 ng/mL)

维生素D缺乏是一个普遍存在的健康问题,越来越多的研究表明,缺乏维生素D会导致各种慢性疾病风险增加,不过对于少数群体,维生素D缺乏是否也会导致代谢性疾病风险增加呢?

研究者对居住在南韩的健康北韩难民进行了一项研究,对纵向队列进行横断面分析。该研究共纳入了386名年龄≥30岁的北韩难民,检测去25(OH)D水平。

研究数据显示参与者中87%的表现维生素D缺乏 (25(OH)D <20 ng/mL) ;没有一个人维生素D是充足的(25(OH)D ≥30 ng/mL)。体重过轻的参与者((BMI) <18 kg/m(2))25(OH)D水平明显低于BMI正常组 (≥18.5 and<23 kg/m(2))。多因素回归分析显示, 校正性别、年龄、季节、居住时长、运动、BMI等之后,25(OH)D水平最低(<10 ng/mL)的人群与25(OH)D ≥20 ng/mL的相比,以下方面风险明显增高:代谢综合征 (OR, 6.37, 95% CI 1.34 to 30.3),高甘油三酯 (OR, 6.71, 95% CI 1.75 to 25.7),低水平高密度脂蛋白(OR, 5.98, 95% CI 1.54 to 23.2) 。

研究结果表明,居住在南韩的北韩难民维生素D缺乏现象很常见。且维生素D缺乏越严重,代谢疾病风险也越高。

原始出处:

Kim KJ, Kim YJ, Kim SH,et al.Vitamin D status and associated metabolic risk factors among North Korean refugees in South Korea: a cross-sectional study.BMJ Open. 2015 Nov 30;5


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    2016-06-22 明崖

    对中国是否也是如此

    0

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    2016-09-09 gaoxiaoe
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    2016-10-24 feather89
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    2016-01-05 xyfg98

    0

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    2016-01-05 三毛坨

    Hj

    0

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    2016-01-05 三毛坨

    o

    0

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    2015-12-27 hixiaoluo

    好文章,值得收藏

    0

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    2015-12-27 hixiaoluo

    好文章,值得收藏

    0

  9. [GetPortalCommentsPageByObjectIdResponse(id=90783, encodeId=6b8690e83bc, content=对中国是否也是如此, beContent=null, objectType=article, channel=null, level=null, likeNumber=80, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=73441710184, createdName=明崖, createdTime=Wed Jun 22 08:38:00 CST 2016, time=2016-06-22, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1847793, encodeId=6310184e79310, content=<a href='/topic/show?id=2977356edc' target=_blank style='color:#2F92EE;'>#BMJ#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=40, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=3567, encryptionId=2977356edc, topicName=BMJ)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=148754, createdName=gaoxiaoe, createdTime=Fri Sep 09 20:53:00 CST 2016, time=2016-09-09, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1725957, encodeId=e1111e259579a, content=<a href='/topic/show?id=986913980dd' target=_blank style='color:#2F92EE;'>#PE#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=45, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=13980, encryptionId=986913980dd, topicName=PE)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=f06c33759375, createdName=feather89, createdTime=Mon Oct 24 22:53:00 CST 2016, time=2016-10-24, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=52252, encodeId=e826522521f, content=赞, beContent=null, objectType=article, channel=null, level=null, likeNumber=102, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=fe261399236, createdName=xyfg98, createdTime=Tue Jan 05 22:35:00 CST 2016, time=2016-01-05, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=52037, encodeId=46095203e00, content=Hj, beContent=null, objectType=article, channel=null, level=null, likeNumber=136, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=43f41674911, createdName=三毛坨, createdTime=Tue Jan 05 12:59:00 CST 2016, time=2016-01-05, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=52038, encodeId=2cbe5203866, content=o, beContent=null, objectType=article, channel=null, level=null, likeNumber=132, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=43f41674911, createdName=三毛坨, createdTime=Tue Jan 05 12:59:00 CST 2016, time=2016-01-05, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=48859, encodeId=89a9488599e, content=好文章,值得收藏, beContent=null, objectType=article, channel=null, level=null, likeNumber=121, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=bc301610909, createdName=hixiaoluo, createdTime=Sun Dec 27 08:23:00 CST 2015, time=2015-12-27, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=48860, encodeId=59a6488608b, content=好文章,值得收藏, beContent=null, objectType=article, channel=null, level=null, likeNumber=89, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=bc301610909, createdName=hixiaoluo, createdTime=Sun Dec 27 08:23:00 CST 2015, time=2015-12-27, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=45394, encodeId=e263453946a, content=有意思, beContent=null, objectType=article, channel=null, level=null, likeNumber=80, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=df9e1651052, createdName=三三五五, createdTime=Wed Dec 09 20:23:00 CST 2015, time=2015-12-09, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1401991, encodeId=ae1a140199198, content=<a href='/topic/show?id=193025463d8' target=_blank style='color:#2F92EE;'>#代谢疾病#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=59, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=25463, encryptionId=193025463d8, topicName=代谢疾病)], attachment=null, authenticateStatus=null, createdAvatar=http://thirdqq.qlogo.cn/qqapp/101296147/F9591315BE4091482318EFFCD39C9D08/100, createdBy=bf9f2374681, createdName=windight, createdTime=Tue Dec 08 12:53:00 CST 2015, time=2015-12-08, status=1, ipAttribution=)]
    2015-12-09 三三五五

    有意思

    0

  10. [GetPortalCommentsPageByObjectIdResponse(id=90783, encodeId=6b8690e83bc, content=对中国是否也是如此, beContent=null, objectType=article, channel=null, level=null, likeNumber=80, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=73441710184, createdName=明崖, createdTime=Wed Jun 22 08:38:00 CST 2016, time=2016-06-22, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1847793, encodeId=6310184e79310, content=<a href='/topic/show?id=2977356edc' target=_blank style='color:#2F92EE;'>#BMJ#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=40, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=3567, encryptionId=2977356edc, topicName=BMJ)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=148754, createdName=gaoxiaoe, createdTime=Fri Sep 09 20:53:00 CST 2016, time=2016-09-09, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1725957, encodeId=e1111e259579a, content=<a href='/topic/show?id=986913980dd' target=_blank style='color:#2F92EE;'>#PE#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=45, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=13980, encryptionId=986913980dd, topicName=PE)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=f06c33759375, createdName=feather89, createdTime=Mon Oct 24 22:53:00 CST 2016, time=2016-10-24, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=52252, encodeId=e826522521f, content=赞, beContent=null, objectType=article, channel=null, level=null, likeNumber=102, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=fe261399236, createdName=xyfg98, createdTime=Tue Jan 05 22:35:00 CST 2016, time=2016-01-05, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=52037, encodeId=46095203e00, content=Hj, beContent=null, objectType=article, channel=null, level=null, likeNumber=136, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=43f41674911, createdName=三毛坨, createdTime=Tue Jan 05 12:59:00 CST 2016, time=2016-01-05, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=52038, encodeId=2cbe5203866, content=o, beContent=null, objectType=article, channel=null, level=null, likeNumber=132, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=43f41674911, createdName=三毛坨, createdTime=Tue Jan 05 12:59:00 CST 2016, time=2016-01-05, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=48859, encodeId=89a9488599e, content=好文章,值得收藏, beContent=null, objectType=article, channel=null, level=null, likeNumber=121, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=bc301610909, createdName=hixiaoluo, createdTime=Sun Dec 27 08:23:00 CST 2015, time=2015-12-27, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=48860, encodeId=59a6488608b, content=好文章,值得收藏, beContent=null, objectType=article, channel=null, level=null, likeNumber=89, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=bc301610909, createdName=hixiaoluo, createdTime=Sun Dec 27 08:23:00 CST 2015, time=2015-12-27, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=45394, encodeId=e263453946a, content=有意思, beContent=null, objectType=article, channel=null, level=null, likeNumber=80, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=df9e1651052, createdName=三三五五, createdTime=Wed Dec 09 20:23:00 CST 2015, time=2015-12-09, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1401991, encodeId=ae1a140199198, content=<a href='/topic/show?id=193025463d8' target=_blank style='color:#2F92EE;'>#代谢疾病#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=59, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=25463, encryptionId=193025463d8, topicName=代谢疾病)], attachment=null, authenticateStatus=null, createdAvatar=http://thirdqq.qlogo.cn/qqapp/101296147/F9591315BE4091482318EFFCD39C9D08/100, createdBy=bf9f2374681, createdName=windight, createdTime=Tue Dec 08 12:53:00 CST 2015, time=2015-12-08, status=1, ipAttribution=)]

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