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阜外医院新材料化学消融治疗肥厚型心肌病,可减少酒精泄露

2018-07-06 朱柳媛 中国循环杂志

阜外医院杨伟宪、乔树宾等人在本刊发文指出,无水酒精联合明胶海绵化学消融治疗肥厚型梗阻性心肌病安全、有效。


阜外医院杨伟宪、乔树宾等人在本刊发文指出,无水酒精联合明胶海绵化学消融治疗肥厚型梗阻性心肌病安全、有效。
 
该研究团队报告了2017年5月至2017年12月在阜外医院接受无水酒精联合明胶海绵化学消融治疗的7 例肥厚型梗阻性心肌病患者资料。
 
7 例患者中男性5 例,女性2 例,中位年龄56岁,平均最大室间隔厚19.6 mm,消融间隔支1~2支,无水酒精用量为1.4 ml,明胶海绵用量0.5 ml。
 
据研究者介绍,这7例患者术后左心室流出道压差下降显著,纽约心脏协会(NYHA)心功能分级明显改善,未发生严重并发症。
 
作者表示,对于药物治疗不能缓解的患者,心肌切除术是治疗肥厚型心肌病的金标准,经皮室间隔无水酒精化学消融术是一种有效的替代方法。
 
化学消融术主要是通过向间隔支注入无水酒精,使部分肥厚的心肌坏死,室间隔变薄,从而解除左心室流出道的梗阻。研究表明该方法总体上安全有效,但也存在一些局限性,如无水酒精漏入前降支或交通支开放导致无水酒精流向非靶目标区域,造成非靶目标心肌梗死
 
因此,研究者在进行酒精化学消融时,对单纯无水酒精消融可能产生不良反应的部分患者,尝试联合使用明胶海绵进行补充消融。作者表示,这是对无水酒精化学消融的一种有益的补充,下一步需要更大样本和更长期的随访来明确这一手术方法的有效性和安全性。
 
原始出处:

刘蓉, 胡奉环, 袁建松, 等. 无水酒精联合明胶海绵化学消融治疗肥厚型梗阻性心肌病疗效分析. 中国循环杂志, 2018, 33: 576-579.

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    2019-01-12 124fc40fm27暂无昵称

    预后如何?

    0

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  5. [GetPortalCommentsPageByObjectIdResponse(id=1816075, encodeId=8c8b18160e5c4, content=<a href='/topic/show?id=fc4e9e348b6' target=_blank style='color:#2F92EE;'>#阜外医#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=122, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=97348, encryptionId=fc4e9e348b6, topicName=阜外医)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=c97a2500111, createdName=thinkibmz_44722594, createdTime=Sat Apr 27 22:31:00 CST 2019, time=2019-04-27, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=357960, encodeId=48d235e960f7, content=预后如何?, beContent=null, objectType=article, channel=null, level=null, likeNumber=81, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=09c02529822, createdName=124fc40fm27暂无昵称, createdTime=Sat Jan 12 20:25:33 CST 2019, time=2019-01-12, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1293671, encodeId=e00212936e1f8, content=<a href='/topic/show?id=4c6e9e34931' target=_blank style='color:#2F92EE;'>#阜外医院#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=97, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=97349, encryptionId=4c6e9e34931, topicName=阜外医院)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=8942242, createdName=jj000001, createdTime=Sun Jul 08 11:31:00 CST 2018, time=2018-07-08, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1421729, encodeId=28cb1421e2951, content=<a href='/topic/show?id=4bc865819d2' target=_blank style='color:#2F92EE;'>#消融#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=107, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=65819, encryptionId=4bc865819d2, topicName=消融)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=1a193676008, createdName=xiangyuzhou972, createdTime=Sun Jul 08 11:31:00 CST 2018, time=2018-07-08, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1597736, encodeId=9864159e73663, content=<a href='/topic/show?id=28986582e02' target=_blank style='color:#2F92EE;'>#消融治疗#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=61, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=65827, encryptionId=28986582e02, topicName=消融治疗)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=f07818523366, createdName=zhishijing, createdTime=Sun Jul 08 11:31:00 CST 2018, time=2018-07-08, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1622338, encodeId=2e3e1622338a3, content=<a href='/topic/show?id=b9578094833' target=_blank style='color:#2F92EE;'>#肌病#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=47, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=80948, encryptionId=b9578094833, topicName=肌病)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=395f25, createdName=爆笑小医, createdTime=Sun Jul 08 11:31:00 CST 2018, time=2018-07-08, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=329954, encodeId=3aae329954e7, content=好, beContent=null, objectType=article, channel=null, level=null, likeNumber=65, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=18741984753, createdName=smartxiuxiu, createdTime=Sat Jul 07 10:14:14 CST 2018, time=2018-07-07, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=329806, encodeId=378b329806a7, content=了解一下.谢谢分享!, beContent=null, objectType=article, channel=null, level=null, likeNumber=111, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://cdnapi.center.medsci.cn/medsci/head/2019/12/23/2f51002e1349ccda5be11c1eea1e1e60.jpg, createdBy=a22097948, createdName=天地飞扬, createdTime=Fri Jul 06 20:35:53 CST 2018, time=2018-07-06, status=1, ipAttribution=)]
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    2018-07-07 smartxiuxiu

    0

  8. [GetPortalCommentsPageByObjectIdResponse(id=1816075, encodeId=8c8b18160e5c4, content=<a href='/topic/show?id=fc4e9e348b6' target=_blank style='color:#2F92EE;'>#阜外医#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=122, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=97348, encryptionId=fc4e9e348b6, topicName=阜外医)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=c97a2500111, createdName=thinkibmz_44722594, createdTime=Sat Apr 27 22:31:00 CST 2019, time=2019-04-27, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=357960, encodeId=48d235e960f7, content=预后如何?, beContent=null, objectType=article, channel=null, level=null, likeNumber=81, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=09c02529822, createdName=124fc40fm27暂无昵称, createdTime=Sat Jan 12 20:25:33 CST 2019, time=2019-01-12, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1293671, encodeId=e00212936e1f8, content=<a href='/topic/show?id=4c6e9e34931' target=_blank style='color:#2F92EE;'>#阜外医院#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=97, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=97349, encryptionId=4c6e9e34931, topicName=阜外医院)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=8942242, createdName=jj000001, createdTime=Sun Jul 08 11:31:00 CST 2018, time=2018-07-08, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1421729, encodeId=28cb1421e2951, content=<a href='/topic/show?id=4bc865819d2' target=_blank style='color:#2F92EE;'>#消融#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=107, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=65819, encryptionId=4bc865819d2, topicName=消融)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=1a193676008, createdName=xiangyuzhou972, createdTime=Sun Jul 08 11:31:00 CST 2018, time=2018-07-08, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1597736, encodeId=9864159e73663, content=<a href='/topic/show?id=28986582e02' target=_blank style='color:#2F92EE;'>#消融治疗#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=61, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=65827, encryptionId=28986582e02, topicName=消融治疗)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=f07818523366, createdName=zhishijing, createdTime=Sun Jul 08 11:31:00 CST 2018, time=2018-07-08, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1622338, encodeId=2e3e1622338a3, content=<a href='/topic/show?id=b9578094833' target=_blank style='color:#2F92EE;'>#肌病#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=47, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=80948, encryptionId=b9578094833, topicName=肌病)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=395f25, createdName=爆笑小医, createdTime=Sun Jul 08 11:31:00 CST 2018, time=2018-07-08, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=329954, encodeId=3aae329954e7, content=好, beContent=null, objectType=article, channel=null, level=null, likeNumber=65, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=18741984753, createdName=smartxiuxiu, createdTime=Sat Jul 07 10:14:14 CST 2018, time=2018-07-07, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=329806, encodeId=378b329806a7, content=了解一下.谢谢分享!, beContent=null, objectType=article, channel=null, level=null, likeNumber=111, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://cdnapi.center.medsci.cn/medsci/head/2019/12/23/2f51002e1349ccda5be11c1eea1e1e60.jpg, createdBy=a22097948, createdName=天地飞扬, createdTime=Fri Jul 06 20:35:53 CST 2018, time=2018-07-06, status=1, ipAttribution=)]
    2018-07-06 天地飞扬

    了解一下.谢谢分享!

    0

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