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乳酸链球菌素或有助抵抗头颈部鳞状细胞癌

2012-11-06 佚名 医学论坛网

  乳酸链球菌素是一种常见的食品防腐剂,美国密西根大学研究者们的最新研究发现,乳酸链球菌素具有减慢甚至是阻止头部或颈部鳞状细胞癌的功能。该研究还发现,乳酸链球素减缓或阻止肿瘤细胞的生长具有偏好性,即乳酸链球素只会阻断肿瘤细胞的增殖,而不会影响健康细胞。   美国密西根大学牙科学院教授,同时也是该研究结果的首席研究者Yvonne Kapila表示:美国食品与药品管理局(FDA)和世界卫生

  乳酸链球菌素是一种常见的食品防腐剂,美国密西根大学研究者们的最新研究发现,乳酸链球菌素具有减慢甚至是阻止头部或颈部鳞状细胞癌的功能。该研究还发现,乳酸链球素减缓或阻止肿瘤细胞的生长具有偏好性,即乳酸链球素只会阻断肿瘤细胞的增殖,而不会影响健康细胞。

  美国密西根大学牙科学院教授,同时也是该研究结果的首席研究者Yvonne Kapila表示:美国食品与药品管理局(FDA)和世界卫生组织(WHO)早就证实乳酸链球素是一种安全的物质。这也就是说,有了食品与药品管理局(FDA)关于乳酸链球素安全性的证实之后,在临床上要测试乳酸链球素具有的抗癌特性,要比重新去测试一种从未在人上测试过的新药要快很多。  

  既往研究发现,在细菌中,像乳酸链球素这类抗菌药,它能改变细菌细胞特性,从而使得细胞保持健康。但它们是否能改变其他细胞(如癌细胞和肿瘤细胞)的特性直到最近科学家们才开始着手研究。

  口腔癌是一种导致全世界人死亡的主要原因,且口腔鳞状细胞癌会导致90%的口腔癌患者死亡。据最近的研究,几十年以来,口腔癌患者的幸存率一直没有得到提高。

  该研究有史以来第一次证实乳酸链球素能促进癌细胞的死亡。研究还发现,乳酸链球素治疗癌症的机理可能是这样的:乳酸链球素能在癌细胞膜表面制造许多小孔,这就使得钙离子能够流入癌细胞,从而导致癌细胞的死亡。目前还不清楚这种乳酸链球素引发的钙离子所导致的癌细胞死亡的具体机理。但科学家明确知道的是钙离子是调控细胞存亡的关键因子。

 

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    2012-11-08 wshxjq
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