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Rheumatology:IBD伴慢性背痛患者中未诊断的中轴型脊柱炎的患病率,二级护理横断面研究

2022-08-26 紫菀款冬 MedSci原创

阐明在常规二级炎症性肠病(IBD)门诊就诊的慢性腰痛患者中,未经风湿病学家确诊的中轴型脊柱炎的患病率。

目的:阐明在常规二级炎症性肠病(IBD)门诊就诊的慢性背痛患者中,未经风湿病学家确诊的中轴型脊柱炎(rheumatologist-verified diagnosis of axial spondyloarthritis,RVD-axSpA)患病率

方法:向在一所大学教学医院的IBD门诊连续就诊的患者发送筛查问卷并纳入以下人群进行风湿病评估——符合资格标准的患者(经胃肠科医生诊断证实,18-80 岁,无接受生物疗法,既往无axSpA诊断);axSpA的诊断概率为中等的人群[自我报告慢性背痛(CBP)>3 月,发病<45 年]。

内容包括医疗审查、体检、患者报告的结果测量、人类白细胞抗原B27、C反应蛋白、骨盆X线照片和axSpA方案磁共振成像。由一组风湿病专家对RVD axSpA进行诊断。

结果:在接触的470名患者中,91名患者自我报告的CBP>3 月,发病<45 年,其中82人符合临床评估条件。

对于在二级护理机构的IBD诊所就诊的未诊断RVD axSpA的患者(自我报告CBP,发病率<45 年),其患病率估计为5%(95%CI 1.3,12.0),平均症状持续时间为12年(S.D.12.4)。

结论:IBD患者中存在明显的axSpA隐性疾病负担。需要胃肠科的适当鉴定和转诊,以潜在地缩短诊断延迟,并让患者获得适当的治疗。

 

文献来源:

Lim CSE, Tremelling M, Hamilton L, et al. Prevalence of undiagnosed axial spondyloarthritis in inflammatory bowel disease patients with chronic back pain: secondary care cross-sectional study [published online ahead of print, 2022 Aug 22]. Rheumatology (Oxford). 2022;keac473. doi:10.1093/rheumatology/keac473

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  6. [GetPortalCommentsPageByObjectIdResponse(id=1935509, encodeId=47241935509ff, content=<a href='/topic/show?id=a161225e258' target=_blank style='color:#2F92EE;'>#中轴型脊柱炎#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=70, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=22572, encryptionId=a161225e258, topicName=中轴型脊柱炎)], attachment=null, authenticateStatus=null, createdAvatar=http://thirdqq.qlogo.cn/qqapp/1103841572/C2EFD5CFB07FE291138AD4FD0C98E3DE/100, createdBy=e3d52500031, createdName=膀胱癌, createdTime=Sun Jul 09 07:49:14 CST 2023, time=2023-07-09, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=2041598, encodeId=744d20415982c, content=<a href='/topic/show?id=a8de6299654' target=_blank style='color:#2F92EE;'>#横断面#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=99, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=62996, encryptionId=a8de6299654, topicName=横断面)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=21015, createdName=heli0118, createdTime=Fri May 26 07:49:14 CST 2023, time=2023-05-26, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=2062612, encodeId=df5c206261249, content=<a href='/topic/show?id=872c15438a4' target=_blank style='color:#2F92EE;'>#Rheumatology#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=88, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=15438, encryptionId=872c15438a4, topicName=Rheumatology)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=3307462, createdName=风铃821, createdTime=Sun Feb 05 03:49:14 CST 2023, time=2023-02-05, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1748518, encodeId=3cb31e4851863, content=<a href='/topic/show?id=01b55366362' target=_blank style='color:#2F92EE;'>#慢性背痛#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=90, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=53663, encryptionId=01b55366362, topicName=慢性背痛)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=674e36152420, createdName=zhanglin3091, createdTime=Mon May 08 22:49:14 CST 2023, time=2023-05-08, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1250836, encodeId=3bb51250836e1, content=<a href='/topic/show?id=7d6f52988e1' target=_blank style='color:#2F92EE;'>#患病率#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=164, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=52988, encryptionId=7d6f52988e1, topicName=患病率)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=f49517, createdName=xinmeili, createdTime=Thu Aug 25 16:49:14 CST 2022, time=2022-08-25, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1263731, encodeId=24a01263e3157, content=<a href='/topic/show?id=75bc930217' target=_blank style='color:#2F92EE;'>#IBD#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=91, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=9302, encryptionId=75bc930217, topicName=IBD)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=fc0372, createdName=bnurmamat, createdTime=Thu Aug 25 16:49:14 CST 2022, time=2022-08-25, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1342059, encodeId=bacf1342059b3, content=<a href='/topic/show?id=c0b8835e6c5' target=_blank style='color:#2F92EE;'>#背痛#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=82, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=83576, encryptionId=c0b8835e6c5, topicName=背痛)], attachment=null, authenticateStatus=null, createdAvatar=https://thirdwx.qlogo.cn/mmopen/vi_32/xkicoVBAnV4HxvdCqC1viaW8wdLQdN9hVP9icgqqDsxC6UVPjfhogdfc2iaU1xNUMVlFl5QicicWrjWQBTsVye5ngOQQ/132, createdBy=f92f2500185, createdName=ms7405317358118777, createdTime=Thu Aug 25 16:49:14 CST 2022, time=2022-08-25, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1440445, encodeId=f5aa144044540, content=<a href='/topic/show?id=6f0e845427f' target=_blank style='color:#2F92EE;'>#脊柱炎#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=78, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=84542, encryptionId=6f0e845427f, topicName=脊柱炎)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=50834728424, createdName=1249898am16暂无昵称, createdTime=Thu Aug 25 16:49:14 CST 2022, time=2022-08-25, status=1, ipAttribution=)]
    2022-08-25 bnurmamat
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