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J Asthma:中度到重度永久过敏性鼻炎对胸腹运动学与呼吸肌功能影响研究

2019-02-01 AlexYang MedSci原创

最近,有研究人员评估了中度到重度永久过敏性鼻炎患者中胸腹运动学、呼吸肌力和膈肌肌电图活性(EAdi)。研究是一个代表性的研究,包括了40名参与者,20名为AR患者,20名为对照。研究发现,AR患者的胸腹运动学受损(胸壁总体积减少)(p=0.004),总呼吸周期(p=0.014)和呼气时间值(P=0.006)均更低。另外,AR患者的腹壁肋骨贡献百分比(p=0.475)和呼吸速率(p=0.019)均增

最近,有研究人员评估了中度到重度永久过敏性鼻炎患者中胸腹运动学、呼吸肌力和膈肌肌电图活性(EAdi)。

研究是一个代表性的研究,包括了40名参与者,20名为AR患者,20名为对照。研究发现,AR患者的胸腹运动学受损(胸壁总体积减少)(p=0.004),总呼吸周期(p=0.014)和呼气时间值(P=0.006)均更低。另外,AR患者的腹壁肋骨贡献百分比(p=0.475)和呼吸速率(p=0.019)均增加。研究还发现肺肋骨潮气量与MIP(r=0.544; p<0.001)、SNIP (r=0.615; p<0.001)和MEP (r=0.604; p<0.001) 存在正相关关系。在调整了年龄、BMI和性别变量后,多变量分析表明AR患者个体的MIP(β=-24.341; p<0.001)、MEP (β =-0.277; p<0.001)、SNIP (β=-34.687; p<0.001)和RMS (β=-0.041; p=0.017)值均更低。

最后,研究人员指出,与对照组相比,中度到重度AR患者具有更差的呼吸肌力、膈肌激活及胸壁体积分布,并且腹部高位对潮气量的贡献更高。他们的发现也支持了上呼吸道和下呼吸道以整体和协同的方式工作的概念。

原始出处:

Silva PFDS, Dornelas de Andrade A, de Andrade LC et al. Impact of moderate-severe persistent allergic rhinitis on thoraco-abdominal kinematics and respiratory muscle function. J Asthma. 18 January 2019.

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    2019-09-15 skhzy
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    2019-02-03 lietome15

    好文,值得点赞!认真学习,应用于实践!谢谢分享给广大同好!

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