Baidu
map

J Clin Periodontol:治疗牙周炎可减少2型糖尿病的全身炎症

2020-05-24 MedSci原创 MedSci原创

本研究旨在评估牙周治疗对2型糖尿病全身炎症的影响。

本研究旨在评估牙周治疗对2型糖尿病全身炎症的影响。

 

招募了患有2型糖尿病(n = 83)和没有糖尿病(对照组,n = 75)的成人,患有牙周炎的参与者接受了牙周治疗并接受了12个月的随访。测定牙周炎症的生物标志物(牙龈沟液白细胞介素-6,肿瘤坏死因子-α,白细胞介素-1β,干扰素-γ,基质金属蛋白酶-8,基质金属蛋白酶-9,脂联素)以及炎症和糖尿病控制的血清标志物(糖化血红蛋白,高敏C反应蛋白,白介素-6,肿瘤坏死因子-α,白介素-1β,干扰素-γ,瘦素,脂联素)。使用结构方程模型评估牙周治疗对口腔和全身炎症的影响。

 

结果显示,从基线到第12个月,牙周治疗显著改善了临床状况,减少了龈沟液的生物标志物。结构方程模型确定,在基线时,糖尿病和牙周炎的患者的全身性炎症明显高于非糖尿病性牙周炎对照(Δ = 0.20,p = .002),口腔炎症组之间无明显差异。与患有牙周炎但非糖尿病的患者相比,患有糖尿病和牙周炎的患者的牙周治疗后全身性炎症的减少程度更大(Δ= -0.25,p = .01)。

 

综上所述,该研究结果表明,糖尿病和牙周炎一起会增加全身性炎症,有证据表明,牙周治疗后,全身炎症会减轻。

 

原始出处:

 

Philip M Preshaw, John J Taylor, et al., Treatment of Periodontitis Reduces Systemic Inflammation in Type 2 Diabetes. J Clin Periodontol. 2020 Feb 27. doi: 10.1111/jcpe.13274.  

版权声明:
本网站所有内容来源注明为“梅斯医学”或“MedSci原创”的文字、图片和音视频资料,版权均属于梅斯医学所有。非经授权,任何媒体、网站或个人不得转载,授权转载时须注明来源为“梅斯医学”。其它来源的文章系转载文章,或“梅斯号”自媒体发布的文章,仅系出于传递更多信息之目的,本站仅负责审核内容合规,其内容不代表本站立场,本站不负责内容的准确性和版权。如果存在侵权、或不希望被转载的媒体或个人可与我们联系,我们将立即进行删除处理。
在此留言
评论区 (4)
#插入话题
  1. [GetPortalCommentsPageByObjectIdResponse(id=1728477, encodeId=0fb31e28477e2, content=<a href='/topic/show?id=986913980dd' target=_blank style='color:#2F92EE;'>#PE#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=55, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=13980, encryptionId=986913980dd, topicName=PE)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=f06c33759375, createdName=feather89, createdTime=Mon Mar 01 02:40:05 CST 2021, time=2021-03-01, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1451256, encodeId=48431451256d0, content=<a href='/topic/show?id=f0476e49582' target=_blank style='color:#2F92EE;'>#牙周#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=51, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=67495, encryptionId=f0476e49582, topicName=牙周)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=4c37265, createdName=医者仁心, createdTime=Tue May 26 12:40:05 CST 2020, time=2020-05-26, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1516574, encodeId=34e915165e4e4, content=<a href='/topic/show?id=3b0329699d3' target=_blank style='color:#2F92EE;'>#全身炎症#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=62, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=29699, encryptionId=3b0329699d3, topicName=全身炎症)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=4f6210986148, createdName=12498dd9m14暂无昵称, createdTime=Tue May 26 12:40:05 CST 2020, time=2020-05-26, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1043133, encodeId=1d24104313307, content=谢谢MedSci提供最新的资讯, beContent=null, objectType=article, channel=null, level=null, likeNumber=84, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=f0620, createdName=misszhang, createdTime=Mon May 25 00:40:05 CST 2020, time=2020-05-25, status=1, ipAttribution=)]
    2021-03-01 feather89
  2. [GetPortalCommentsPageByObjectIdResponse(id=1728477, encodeId=0fb31e28477e2, content=<a href='/topic/show?id=986913980dd' target=_blank style='color:#2F92EE;'>#PE#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=55, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=13980, encryptionId=986913980dd, topicName=PE)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=f06c33759375, createdName=feather89, createdTime=Mon Mar 01 02:40:05 CST 2021, time=2021-03-01, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1451256, encodeId=48431451256d0, content=<a href='/topic/show?id=f0476e49582' target=_blank style='color:#2F92EE;'>#牙周#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=51, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=67495, encryptionId=f0476e49582, topicName=牙周)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=4c37265, createdName=医者仁心, createdTime=Tue May 26 12:40:05 CST 2020, time=2020-05-26, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1516574, encodeId=34e915165e4e4, content=<a href='/topic/show?id=3b0329699d3' target=_blank style='color:#2F92EE;'>#全身炎症#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=62, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=29699, encryptionId=3b0329699d3, topicName=全身炎症)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=4f6210986148, createdName=12498dd9m14暂无昵称, createdTime=Tue May 26 12:40:05 CST 2020, time=2020-05-26, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1043133, encodeId=1d24104313307, content=谢谢MedSci提供最新的资讯, beContent=null, objectType=article, channel=null, level=null, likeNumber=84, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=f0620, createdName=misszhang, createdTime=Mon May 25 00:40:05 CST 2020, time=2020-05-25, status=1, ipAttribution=)]
  3. [GetPortalCommentsPageByObjectIdResponse(id=1728477, encodeId=0fb31e28477e2, content=<a href='/topic/show?id=986913980dd' target=_blank style='color:#2F92EE;'>#PE#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=55, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=13980, encryptionId=986913980dd, topicName=PE)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=f06c33759375, createdName=feather89, createdTime=Mon Mar 01 02:40:05 CST 2021, time=2021-03-01, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1451256, encodeId=48431451256d0, content=<a href='/topic/show?id=f0476e49582' target=_blank style='color:#2F92EE;'>#牙周#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=51, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=67495, encryptionId=f0476e49582, topicName=牙周)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=4c37265, createdName=医者仁心, createdTime=Tue May 26 12:40:05 CST 2020, time=2020-05-26, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1516574, encodeId=34e915165e4e4, content=<a href='/topic/show?id=3b0329699d3' target=_blank style='color:#2F92EE;'>#全身炎症#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=62, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=29699, encryptionId=3b0329699d3, topicName=全身炎症)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=4f6210986148, createdName=12498dd9m14暂无昵称, createdTime=Tue May 26 12:40:05 CST 2020, time=2020-05-26, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1043133, encodeId=1d24104313307, content=谢谢MedSci提供最新的资讯, beContent=null, objectType=article, channel=null, level=null, likeNumber=84, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=f0620, createdName=misszhang, createdTime=Mon May 25 00:40:05 CST 2020, time=2020-05-25, status=1, ipAttribution=)]
  4. [GetPortalCommentsPageByObjectIdResponse(id=1728477, encodeId=0fb31e28477e2, content=<a href='/topic/show?id=986913980dd' target=_blank style='color:#2F92EE;'>#PE#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=55, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=13980, encryptionId=986913980dd, topicName=PE)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=f06c33759375, createdName=feather89, createdTime=Mon Mar 01 02:40:05 CST 2021, time=2021-03-01, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1451256, encodeId=48431451256d0, content=<a href='/topic/show?id=f0476e49582' target=_blank style='color:#2F92EE;'>#牙周#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=51, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=67495, encryptionId=f0476e49582, topicName=牙周)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=4c37265, createdName=医者仁心, createdTime=Tue May 26 12:40:05 CST 2020, time=2020-05-26, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1516574, encodeId=34e915165e4e4, content=<a href='/topic/show?id=3b0329699d3' target=_blank style='color:#2F92EE;'>#全身炎症#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=62, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=29699, encryptionId=3b0329699d3, topicName=全身炎症)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=4f6210986148, createdName=12498dd9m14暂无昵称, createdTime=Tue May 26 12:40:05 CST 2020, time=2020-05-26, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1043133, encodeId=1d24104313307, content=谢谢MedSci提供最新的资讯, beContent=null, objectType=article, channel=null, level=null, likeNumber=84, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=f0620, createdName=misszhang, createdTime=Mon May 25 00:40:05 CST 2020, time=2020-05-25, status=1, ipAttribution=)]
    2020-05-25 misszhang

    谢谢MedSci提供最新的资讯

    0

相关资讯

手劲儿小提示有糖尿病风险!天津慢性炎症与健康促进队列研究

糖尿病前期是我国日益严重的健康问题,是糖尿病和心血管疾病的高危状态。

JACC:单用替卡格雷对伴有糖尿病PCI患者的影响

经皮冠状动脉介入治疗(PCI)后,短暂的双抗血小板治疗后单用P2Y12抑制剂替卡格雷可以减少出血,而不会增加缺血损伤。然而,这种方法对伴有糖尿病患者的影响尚不清楚。本研究的目的旨在比较和评估替卡格雷和

Semin Arthritis Rheu:类风湿性关节炎中与羟氯喹、甲氨蝶呤、生物制剂和糖皮质激素相关的糖尿病

在RA患者中,羟氯喹、甲氨蝶呤和TNFi与患糖尿病的风险降低相关,而糖皮质激素与糖尿病的风险升高相关。

糖尿病合并低血糖患者的福音!FDA接受dasiglucagon HypoPal“救援笔”用于严重低血糖的新药申请

Zealand是一家生物技术公司,近日宣布,美国食品药品监督管理局(FDA)已接受该公司dasiglucagon HypoPal“救援笔”治疗糖尿病低血糖的新药申请(NDA)。

J Appl Oral Sci:牙周治疗对牙周炎和糖尿病患者的影响

关于2型糖尿病(T2D)和牙周炎患者的牙周治疗对血糖控制和全身炎症的影响尚无定论。本研究旨在评估洁治和根面平整(SRP)对2型糖尿病(T2D)患者的代谢控制和全身炎症的影响。

Sci adv:蓝藻 “创可贴” 或加速糖尿病患者伤口修复

近日,刊登于《科学进展》的研究成果显示,一种由活的蓝藻制成的皮肤贴片可加速小鼠的伤口愈合,并可能有助于治疗糖尿病患者的慢性伤口。

Baidu
map
Baidu
map
Baidu
map