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2型糖尿病患者中医证型分析

2021-08-22 August MedSci原创

据相关报道显示,糖尿病的发病率呈逐年增长趋势,已经成为危害人类健康的三大慢性病之一,通常由于患者受到多种因素的干扰所致。

     随着患病率的不断上升,糖尿病(diabetesmellitus,DM)已经成为严重威胁人类健康的慢性非传染性疾病。中医药在治疗DM及其并发症方面有着整体调节、显著改善临床症状、有效延缓病情进展的独特优势,因此研究DM中医证型特点,对进一步认识DM病程阶段,以及辨证论治、判断预后有重要指导意义。

     2型糖尿病(T2DM)属中医学“消渴病”范畴,消渴病病机为“阴虚为本,燥热为标”,消渴日久,燥热更伤阴液则气阴两伤,日久阴阳两虚,兼有湿、痰、浊、 瘀等实邪,其病机的演变与研究结果一致。因此,在T2DM进展过程中,气阴两虚证为主要证型;体重正常的患者兼证以血瘀为主,超重和肥胖的患者兼证以痰湿、湿热为主。在T2DM治疗过程中,对超重或者肥胖的T2DM患者,在益气养阴的同时应重视健脾祛湿化痰;对体重正常的T2DM 患者,在益气养阴的同时应注重活血化瘀

通过中医证型自主症状的研究,调查发现,中医证型分布主要为气阴两虚、阴虚燥热、痰湿中阻,三种中医证型的腰臀比、BMI、病程及年龄比较差异有统计学意义(P<0.05),其90例2型糖尿病患者中,气阴两虚患者主要容易出现肢体麻痛、气短、心烦等自主症状;阴虚燥热患者易出现口渴引饮、脘腹胀满、心烦等自主症状;而痰湿中阻患者易出现肢体麻痛、气短、心悸怔忡、自汗盗汗等自主症状,气阴两虚患者并发症发生率为100.00%,阴虚燥热为76.00%,痰湿中阻为68.00%。结论是2型糖尿病患者中医证型分布主要为气阴两虚、阴虚燥热、痰湿中阻,各中医证型患者的临床指标具有较大差异,患者易出现自汗盗汗、气短、头晕等临床症状,并发症发生率较高

糖尿病周围神经病变(diabetic peripheral neuopathy,DPN)是糖尿病最常见且严重的并发症。DPN 的临床表现为肢体疼痛、麻木、感觉异常、甚至肌肉萎缩等,是引起感染、坏疽、截肢的最主要原因之一,严重影响糖尿病患者的生存和生活质量。 结果是DPN各证出现频率为,气虚血瘀证 > 寒凝血瘀证 > 肝肾亏虚证 > 痰瘀阻络证 > 阴虚血瘀证。不同病程、TSS评分、C 肽在各证频数分布上有差异(P < 0.05)。结论:DPN 中医证型分布存在一定规律,且与临床指标相关。

参考文献:沙雯君,雷涛.2型糖尿病周围神经病变中医证型分布规律分析[J].世界最新医学信息文摘,2019,19(88):228-229.

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    2021-08-22 misszhang

    谢谢MedSci提供最新的资讯

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    2021-08-22 运动yd

    中医中药,大多被人诋毁,不过梅斯里总是客观公正的

    0

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