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ESC Heart Failure:非侵入性方法测量慢性心力衰竭患者身体成分结果比较

2021-07-04 MedSci原创 MedSci原创

恶病质(cachexia)亦称恶液质。表现为极度消瘦,皮包骨头,形如骷髅,贫血,无力,完全卧床,生活不能自理,极度痛苦,全身衰竭等综合征,在慢性心力衰竭 (CHF)患者 中很常见,

恶病质(cachexia)亦称恶液质。表现为极度消瘦,皮包骨头,形如骷髅,贫血,无力,完全卧床,生活不能自理,极度痛苦,全身衰竭等综合征,在慢性心力衰竭 (CHF)患者 中很常见,患病率为5%15%然而,由于细胞外液的变化,检测CHF患者的恶病质尤其具有挑战性。

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近日,发表在ESC Heart Failure杂志的一项研究通过双能 X 射线吸收仪 (DEXA) 和多频生物电阻抗分析 (BIA) 设备测量了身体成分。研究人员评估了平均年龄为70岁的120CHF患者的身体成分。植入心脏除颤器或起搏器的患者被排除在外,因为此类患者禁用生物电阻抗测量。不能平躺或超过 DEXA 机器 150 公斤体重限制的患者也被排除在外。所有患者在同一天进行两次身体成分评估,其中还包括完整的血管临床病史和检查、血液检查、心电图和超声心动图等。

结果显示,BIA测量的平均脂肪量 (FM) 27.2 (11.7) kg,而DEXA测量的FM32.3 (12.2) kgBIA 的平均 (SD) 瘦体重 (LM) 56.6 (10.9) kg,而DEXA 51.1 (9.9) kgBIA测量的平均骨量(BM)为3.00.5kg,而DEXA 2.80.6kgDEXABIA身体成分测量与其他身体尺寸测量(身体质量指数、臀围和腰围)都有很好的相关性。

BIA DEXA 测量的身体成分

该研究结果证实并扩展了其他科学家将DEXA BIA 进行比较的结果。用于评估身体成分的设备不可互换。尽管 DEXA 是一种辐射源,但它仍是人体成分分析的参考方法。BIA 设备可以在门诊就诊的同时快速评估身体成分,可能更方便,但需要在恶病质研究中进一步验证。

总之,DEXA BIA两种技术在 FMLM BM 的测量上存在差异,不应互换使用。

原始出处

Parin Shah.et al.A comparison of non-invasive methods of measuring body composition in patients with heart failure: a report from SICA-HF.ESC Heart Failure https://doi.org/10.1002/ehf2.13402

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    2021-07-06 zhaojie88
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    2021-07-06 slcumt

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简要介绍:心力衰竭(心衰)是一种临床综合征,定义为由于任何心脏结构或功能异常导致心室充盈或射血能力受损的一组复杂临床综合征。其主要临床表现为呼吸困难和乏力(活动耐量受限)以及液体潴留(肺淤血和外周水肿)。 该指南从基层医疗卫生机构的实际工作出发,在心力衰竭早期识别与诊断、转诊和社区管理、患者自我管理和家庭管理方面给出了明确的指导。

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