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JAMA Intern Med:不同社会经济地位2型糖尿病患者的死亡率研究

2016-08-05 Mechront 译 MedSci原创

目的:评估收入、教育水平、婚姻状况、出生国与2型糖尿病患者的全因、心血管相关、糖尿病相关和癌症相关死亡率的联系。方法:研究包括217364名年龄不足70岁的瑞典国家糖尿病登记的2型糖尿病患者,使用Cox比例风险回归模型对高达17的协变量进行分析。获取全因、心血管相关、糖尿病相关和癌症相关死亡率等数据。结果:217364名纳入研究的患者其平均年龄(SD)为58.3(9.3)岁,其中130839(60

目的:评估收入、教育水平、婚姻状况、出生国与2型糖尿病患者的全因、心血管相关、糖尿病相关和癌症相关死亡率的联系。

方法:研究包括217364名年龄不足70岁的瑞典国家糖尿病登记的2型糖尿病患者,使用Cox比例风险回归模型对高达17的协变量进行分析。获取全因、心血管相关、糖尿病相关和癌症相关死亡率等数据。

结果:217364名纳入研究的患者其平均年龄(SD)为58.3(9.3)岁,其中130839(60.2%)为男性。研究期间共发生了19105例全因死亡,心血管相关、糖尿病相关和癌症相关死亡数据分别为11423 (59.8%)、6984 (36.6%)和6438 (33.7%)。

使用充分调整模型,与单身相比,已婚人士的全因、心血管相关、糖尿病相关死亡风险HR分别为0.73 (95% CI, 0.70-0.77)、0.67 (95% CI, 0.63-0.71)、0.62 (95% CI, 0.57-0.67)。婚姻状况并不与总体癌症死亡率相关,但已婚男性和单身男人相比,前列腺癌死亡风险降低33%,HR=0.67 (95% CI, 0.50-0.90)。最低和最高收入群体的全因、心血管相关、糖尿病相关和癌症相关死亡风险HR分别为1.71 (95% CI, 1.60-1.83)、1.87 (95% CI, 1.72-2.05)、 1.80 (95% CI, 1.61-2.01)和1.28 (95% CI, 1.14-1.44)。与当地的瑞典人相比,非西方移民者的全因、心血管相关、糖尿病相关和癌症相关死亡风险HR分别为0.55 (95% CI, 0.48-0.63)、0.46 (95% CI, 0.38-0.56)、0.38 (95% CI, 0.29-0.49)和0.72 (95% CI, 0.58-0.88)。对于那些具有大专以上学历,与9年或更少的教育者相比,全因、心血管相关和癌症相关死亡风险HR分别为0.85 (95% CI, 0.80-0.90)、0.84 (95% CI, 0.78-0.91)和0.84 (95% CI, 0.76-0.93)。

结论:社会经济地位是功能强大的全因死亡率和心血管死亡率的独立的危险因素,但是不是癌症死亡率的强预测因素。

原始出处:

Rawshani A, Svensson AM,et al.Association Between Socioeconomic Status and Mortality, Cardiovascular Disease, and Cancer in Patients With Type 2 Diabetes.JAMA Intern Med. 2016 Aug 1;176(8):1146-54. doi: 10.1001/jamainternmed.2016.2940.

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    2016-09-20 1e10c84am36(暂无匿称)

    文章很好,非常有益

    0

  4. 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createdBy=552a19396740, createdName=ms3994565386320060, createdTime=Sun Aug 07 01:50:00 CST 2016, time=2016-08-07, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1616651, encodeId=04011616651f0, content=<a href='/topic/show?id=e660e3936c0' target=_blank style='color:#2F92EE;'>#社会#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=39, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=73936, encryptionId=e660e3936c0, topicName=社会)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=e6de19781024, createdName=ms705947299214030, createdTime=Sun Aug 07 01:50:00 CST 2016, time=2016-08-07, status=1, ipAttribution=)]
    2016-09-13 舒心和人

    学习了,感谢分享

    0

  5. 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createdBy=552a19396740, createdName=ms3994565386320060, createdTime=Sun Aug 07 01:50:00 CST 2016, time=2016-08-07, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1616651, encodeId=04011616651f0, content=<a href='/topic/show?id=e660e3936c0' target=_blank style='color:#2F92EE;'>#社会#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=39, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=73936, encryptionId=e660e3936c0, topicName=社会)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=e6de19781024, createdName=ms705947299214030, createdTime=Sun Aug 07 01:50:00 CST 2016, time=2016-08-07, status=1, ipAttribution=)]
    2016-09-11 1e10c84am36(暂无匿称)

    己拜读,受益匪浅

    0

  6. 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  7. 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  8. 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  9. 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  10. 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