Moderna宣布其新冠疫苗mRNA-1273有效率达94.5％

2020-11-16 MedSci原创 MedSci原创

Moderna指出，在第一次中期分析中发现了11例严重COVID-19病例，而这些病例均发生在安慰剂组。

Moderna今天宣布了III期COVE研究的首次中期分析结果，结果显示其新冠病毒COVID-19疫苗mRNA-1273的有效率达94.5％。该分析共确诊95例新冠病毒感染患者，其中安慰剂组90例，而mRNA-1273组仅为5例。

图片来源：uk.reuters.com

Moderna计划在未来几周内寻求FDA的紧急使用许可，该文件将以151例患者的最终分析为基础，平均随访时间超过2个月。

COVE研究目前正在美国30000名年龄在18岁及以上、有重大COVID-19感染风险的参与者中评估100 mcg剂量COVID-19疫苗mRNA-1273的疗效。受试者给药两次，间隔28天。该试验的主要终点是预防有症状的COVID-19疾病，主要的次要目标包括预防严重的COVID-19疾病和预防SARS-CoV-2感染。

Moderna指出，在第一次中期分析中发现了11例严重COVID-19病例，而这些病例均发生在安慰剂组。

mRNA新冠疫苗作用机理（图片来源：NIH官网）

原始出处：

https://www.firstwordpharma.com/node/1774578?tsid=4

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2021-05-12 般若傻瓜

#eRNA#

55 0
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2021-06-15 liao1619

#mRNA-1273#

57 0
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2020-11-20 药师小王

好消息啊

110 0
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2020-11-17 杨群

涨知识，祖国继续加油

0 0
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2020-11-17 lovetcm

国内疫苗仍有差距！陈院士疫苗，科兴疫苗未知数比较多。国药灭活疫苗最靠谱，但比不上mRNA疫苗，对抗病毒突变能力差，效果也达不到90%

135 0
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2020-11-17 公卫新人

新冠肺炎，疫情何时才能消失

71 0
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2020-11-17 杏林小小

#mRNA-1273#

51 0
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2020-11-16 ms2000001051330459

学习了，涨知识了！

108 0

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Moderna宣布其新冠疫苗mRNA-1273有效率达94.5％

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