AJNR：儿童烟雾病患者间接血管重建术后脑血流量的增加：动脉自旋标记MRI

2016-04-16 MedSci MedSci原创

研究背景和研究目的：烟雾病的严重性通常用传统的血管造影来衡量。动脉自旋标记的MR图像现在被认为是一种无创的定量脑血流量的方法。这个研究旨在通过动脉自旋标记MR图像的统计参数图分析进行手术后的烟雾病儿童患者的脑血流量变化研究材料和方法：我们纳入了2011年到2013年通过多颅骨钻孔性间接脑血管重建治疗的15位儿童患者。使用SPM8按照广义线性模型对术前及术后3个月及12个月的动脉自旋标记序列及T1序

研究背景和研究目的：烟雾病的严重性通常用传统的血管造影来衡量。动脉自旋标记的MR图像现在被认为是一种无创的定量脑血流量的方法。这个研究旨在通过动脉自旋标记MR图像的统计参数图分析进行手术后的烟雾病儿童患者的脑血流量变化

研究材料和方法：我们纳入了2011年到2013年通过多颅骨钻孔性间接脑血管重建治疗的15位儿童患者。使用SPM8按照广义线性模型对术前及术后3个月及12个月的动脉自旋标记序列及T1序列进行分析。组间进行体素分析，比较所有的病变半球和健侧半球，在个体水平，对每个病人同对照组进行比较。

研究结果：组间分析显示具有统计学差异的烟雾病患者患侧半球术前大脑中动脉供血区灌注不足以及血管重建后相同供血区灌注明显的增加(P < .05多重比较谬误纠正后)。术前，协同DSA定位的个体分析显示病变区域显著的灌注不足。血管重建术后，仅一位病人灌注无明显改善，与临床数据相符合。

研究结论：使用SPM分析动脉自旋标记MR提供一种无创的术前脑血流动力学缺损的评估，和儿童烟雾病患者术后改善的客观评估。

原始出处：

Blauwblomme T1, Lemaitre H2, Naggara O3, Calmon R4, Kossorotoff M5, et al,Cerebral Blood Flow Improvement after Indirect Revascularization for Pediatric Moyamoya Disease: A Statistical Analysis of Arterial Spin-Labeling MRI. Am J Neuroradiol. 2016 Apr;37(4):706-12. doi: 10.3174/ajnr.A4592. Epub 2015 Nov 19

版权声明：
本网站所有内容来源注明为“梅斯医学”或“MedSci原创”的文字、图片和音视频资料，版权均属于梅斯医学所有。非经授权，任何媒体、网站或个人不得转载，授权转载时须注明来源为“梅斯医学”。其它来源的文章系转载文章，或“梅斯号”自媒体发布的文章，仅系出于传递更多信息之目的，本站仅负责审核内容合规，其内容不代表本站立场，本站不负责内容的准确性和版权。如果存在侵权、或不希望被转载的媒体或个人可与我们联系，我们将立即进行删除处理。
在此留言

评论区 (5)

#插入话题

插入图片

[GetPortalCommentsPageByObjectIdResponse(id=2042254, encodeId=742a2042254b4, content=<a href='/topic/show?id=754b8508329' target=_blank style='color:#2F92EE;'>#脑血流#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=77, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=85083, encryptionId=754b8508329, topicName=脑血流)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=b191324, createdName=marongnuan, createdTime=Mon Sep 12 16:18:00 CST 2016, time=2016-09-12, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=2075892, encodeId=4bc820e58922a, content=<a href='/topic/show?id=b208891e986' target=_blank style='color:#2F92EE;'>#血流量#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=104, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=89179, encryptionId=b208891e986, topicName=血流量)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=a691420, createdName=30397604, createdTime=Sun Dec 11 01:18:00 CST 2016, time=2016-12-11, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=2077861, encodeId=3c8620e786116, content=<a href='/topic/show?id=5bb63332374' target=_blank style='color:#2F92EE;'>#动脉自旋标记MRI#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=62, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=33323, encryptionId=5bb63332374, topicName=动脉自旋标记MRI)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=72bf2500198, createdName=小小小向日葵, createdTime=Tue Apr 19 20:18:00 CST 2016, time=2016-04-19, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1986789, encodeId=d87c1986e8975, content=<a href='/topic/show?id=e21b2834245' target=_blank style='color:#2F92EE;'>#儿童烟雾病#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=69, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=28342, encryptionId=e21b2834245, topicName=儿童烟雾病)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=568152, createdName=snowpeakxu, createdTime=Fri Apr 29 06:18:00 CST 2016, time=2016-04-29, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1771562, encodeId=b2961e715625d, content=<a href='/topic/show?id=0a91333227e' target=_blank style='color:#2F92EE;'>#动脉自旋标记#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=103, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=33322, encryptionId=0a91333227e, topicName=动脉自旋标记)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=dc0d38318388, createdName=xjy15, createdTime=Mon Oct 03 07:18:00 CST 2016, time=2016-10-03, status=1, ipAttribution=)]
2016-09-12 marongnuan

#脑血流#

77 0
[GetPortalCommentsPageByObjectIdResponse(id=2042254, encodeId=742a2042254b4, content=<a href='/topic/show?id=754b8508329' target=_blank style='color:#2F92EE;'>#脑血流#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=77, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=85083, encryptionId=754b8508329, topicName=脑血流)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=b191324, createdName=marongnuan, createdTime=Mon Sep 12 16:18:00 CST 2016, time=2016-09-12, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=2075892, encodeId=4bc820e58922a, content=<a href='/topic/show?id=b208891e986' target=_blank style='color:#2F92EE;'>#血流量#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=104, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=89179, encryptionId=b208891e986, topicName=血流量)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=a691420, createdName=30397604, createdTime=Sun Dec 11 01:18:00 CST 2016, time=2016-12-11, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=2077861, encodeId=3c8620e786116, content=<a href='/topic/show?id=5bb63332374' target=_blank style='color:#2F92EE;'>#动脉自旋标记MRI#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=62, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=33323, encryptionId=5bb63332374, topicName=动脉自旋标记MRI)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=72bf2500198, createdName=小小小向日葵, createdTime=Tue Apr 19 20:18:00 CST 2016, time=2016-04-19, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1986789, encodeId=d87c1986e8975, content=<a href='/topic/show?id=e21b2834245' target=_blank style='color:#2F92EE;'>#儿童烟雾病#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=69, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=28342, encryptionId=e21b2834245, topicName=儿童烟雾病)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=568152, createdName=snowpeakxu, createdTime=Fri Apr 29 06:18:00 CST 2016, time=2016-04-29, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1771562, encodeId=b2961e715625d, content=<a href='/topic/show?id=0a91333227e' target=_blank style='color:#2F92EE;'>#动脉自旋标记#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=103, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=33322, encryptionId=0a91333227e, topicName=动脉自旋标记)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=dc0d38318388, createdName=xjy15, createdTime=Mon Oct 03 07:18:00 CST 2016, time=2016-10-03, status=1, ipAttribution=)]
2016-12-11 30397604

#血流量#

104 0
[GetPortalCommentsPageByObjectIdResponse(id=2042254, encodeId=742a2042254b4, content=<a href='/topic/show?id=754b8508329' target=_blank style='color:#2F92EE;'>#脑血流#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=77, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=85083, encryptionId=754b8508329, topicName=脑血流)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=b191324, createdName=marongnuan, createdTime=Mon Sep 12 16:18:00 CST 2016, time=2016-09-12, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=2075892, encodeId=4bc820e58922a, content=<a href='/topic/show?id=b208891e986' target=_blank style='color:#2F92EE;'>#血流量#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=104, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=89179, encryptionId=b208891e986, topicName=血流量)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=a691420, createdName=30397604, createdTime=Sun Dec 11 01:18:00 CST 2016, time=2016-12-11, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=2077861, encodeId=3c8620e786116, content=<a href='/topic/show?id=5bb63332374' target=_blank style='color:#2F92EE;'>#动脉自旋标记MRI#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=62, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=33323, encryptionId=5bb63332374, topicName=动脉自旋标记MRI)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=72bf2500198, createdName=小小小向日葵, createdTime=Tue Apr 19 20:18:00 CST 2016, time=2016-04-19, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1986789, encodeId=d87c1986e8975, content=<a href='/topic/show?id=e21b2834245' target=_blank style='color:#2F92EE;'>#儿童烟雾病#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=69, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=28342, encryptionId=e21b2834245, topicName=儿童烟雾病)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=568152, createdName=snowpeakxu, createdTime=Fri Apr 29 06:18:00 CST 2016, time=2016-04-29, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1771562, encodeId=b2961e715625d, content=<a href='/topic/show?id=0a91333227e' target=_blank style='color:#2F92EE;'>#动脉自旋标记#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=103, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=33322, encryptionId=0a91333227e, topicName=动脉自旋标记)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=dc0d38318388, createdName=xjy15, createdTime=Mon Oct 03 07:18:00 CST 2016, time=2016-10-03, status=1, ipAttribution=)]
2016-04-19 小小小向日葵

#动脉自旋标记MRI#

62 0
[GetPortalCommentsPageByObjectIdResponse(id=2042254, encodeId=742a2042254b4, content=<a href='/topic/show?id=754b8508329' target=_blank style='color:#2F92EE;'>#脑血流#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=77, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=85083, encryptionId=754b8508329, topicName=脑血流)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=b191324, createdName=marongnuan, createdTime=Mon Sep 12 16:18:00 CST 2016, time=2016-09-12, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=2075892, encodeId=4bc820e58922a, content=<a href='/topic/show?id=b208891e986' target=_blank style='color:#2F92EE;'>#血流量#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=104, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=89179, encryptionId=b208891e986, topicName=血流量)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=a691420, createdName=30397604, createdTime=Sun Dec 11 01:18:00 CST 2016, time=2016-12-11, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=2077861, encodeId=3c8620e786116, content=<a href='/topic/show?id=5bb63332374' target=_blank style='color:#2F92EE;'>#动脉自旋标记MRI#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=62, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=33323, encryptionId=5bb63332374, topicName=动脉自旋标记MRI)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=72bf2500198, createdName=小小小向日葵, createdTime=Tue Apr 19 20:18:00 CST 2016, time=2016-04-19, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1986789, encodeId=d87c1986e8975, content=<a href='/topic/show?id=e21b2834245' target=_blank style='color:#2F92EE;'>#儿童烟雾病#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=69, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=28342, encryptionId=e21b2834245, topicName=儿童烟雾病)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=568152, createdName=snowpeakxu, createdTime=Fri Apr 29 06:18:00 CST 2016, time=2016-04-29, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1771562, encodeId=b2961e715625d, content=<a href='/topic/show?id=0a91333227e' target=_blank style='color:#2F92EE;'>#动脉自旋标记#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=103, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=33322, encryptionId=0a91333227e, topicName=动脉自旋标记)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=dc0d38318388, createdName=xjy15, createdTime=Mon Oct 03 07:18:00 CST 2016, time=2016-10-03, status=1, ipAttribution=)]
2016-04-29 snowpeakxu

#儿童烟雾病#

69 0
[GetPortalCommentsPageByObjectIdResponse(id=2042254, encodeId=742a2042254b4, content=<a href='/topic/show?id=754b8508329' target=_blank style='color:#2F92EE;'>#脑血流#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=77, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=85083, encryptionId=754b8508329, topicName=脑血流)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=b191324, createdName=marongnuan, createdTime=Mon Sep 12 16:18:00 CST 2016, time=2016-09-12, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=2075892, encodeId=4bc820e58922a, content=<a href='/topic/show?id=b208891e986' target=_blank style='color:#2F92EE;'>#血流量#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=104, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=89179, encryptionId=b208891e986, topicName=血流量)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=a691420, createdName=30397604, createdTime=Sun Dec 11 01:18:00 CST 2016, time=2016-12-11, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=2077861, encodeId=3c8620e786116, content=<a href='/topic/show?id=5bb63332374' target=_blank style='color:#2F92EE;'>#动脉自旋标记MRI#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=62, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=33323, encryptionId=5bb63332374, topicName=动脉自旋标记MRI)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=72bf2500198, createdName=小小小向日葵, createdTime=Tue Apr 19 20:18:00 CST 2016, time=2016-04-19, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1986789, encodeId=d87c1986e8975, content=<a href='/topic/show?id=e21b2834245' target=_blank style='color:#2F92EE;'>#儿童烟雾病#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=69, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=28342, encryptionId=e21b2834245, topicName=儿童烟雾病)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=568152, createdName=snowpeakxu, createdTime=Fri Apr 29 06:18:00 CST 2016, time=2016-04-29, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1771562, encodeId=b2961e715625d, content=<a href='/topic/show?id=0a91333227e' target=_blank style='color:#2F92EE;'>#动脉自旋标记#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=103, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=33322, encryptionId=0a91333227e, topicName=动脉自旋标记)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=dc0d38318388, createdName=xjy15, createdTime=Mon Oct 03 07:18:00 CST 2016, time=2016-10-03, status=1, ipAttribution=)]
2016-10-03 xjy15

#动脉自旋标记#

103 0

内科

外科

专科科室

热点

按科室浏览

临床工具

科研工具

其他工具

科研数智化

真实世界研究解决方案

数字化学术传播解决方案

其它

神经科

AJNR：儿童烟雾病患者间接血管重建术后脑血流量的增加：动脉自旋标记MRI

相关资讯

科室

工具

服务

神经科

AJNR：儿童烟雾病患者间接血管重建术后脑血流量的增加：动脉自旋标记MRI

相关资讯

Stroke：2454例入院治疗儿童烟雾病患者及医院大小对结局影响的分析

警惕烟雾病儿童脑血流突然下降

科室

工具

服务