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Circ: Cardiovasc Inte:经导管主动脉瓣置换术后左心室心肌功能的预后相关因素

2019-01-11 xiangting MedSci原创

左心室心肌做功指数Tei与经导管主动脉瓣置换术后长短期随访期间的临床结局受损有关。

左心室心肌做功指数Tei是一个超声心动图参数,其包含了收缩期和舒张期时间间隔的信息。虽然经导管主动脉瓣置换术后收缩和舒张参数的预后价值已得到了很好研究,但尚未评估Tei在这种情况下的作用。

纳入2007年8月至2015年12月经导管主动脉瓣置换术前、后接受过经胸超声心动图检查的连续症状性严重主动脉瓣狭窄患者。主要终点是TAVR后的1年全因死亡率。在有计算Tei超声心动图图像的824名患者中,639名患者的pre-Tei正常(<0.45),185名患者升高(≥0.45),而602名患者的post-Tei正常,120名患者升高。在调整混杂因素后,pre-Tei升高与30天(校正风险比[HRadj] 3.62; 95%CI,1.89-6.91)和1年的全因死亡风险升高相关(HRadj 2.56; 95%CI,1.78-3.69)。同样,post-Tei与30天和1年随访期间的死亡风险升高相关(HRadj 6.70; 95%CI,4.22-10.63)。在多因素分析中Tei可分别作为早期(每0.1- HRadj的pre-Tei指数1.40; 95%CI,1.23-1.60)和晚期死亡率的独立预测因子(每0.1-HRadj的post-Tei指数1.40; 95%CI,1.31-1.50)。

左心室心肌做功指数Tei与经导管主动脉瓣置换术后长短期随访期间的临床结局受损有关。

原始出处:

Masahiko Asami. Prognostic Relevance of Left Ventricular Myocardial Performance After Transcatheter Aortic Valve Replacement. Circ: Cardiovascular Interventions. 10 January 2019.

本文系梅斯医学(MedSci)原创编译整理,转载需授权!

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    2019-02-28 quxin068
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    2019-02-15 yxch48
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  5. 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  6. 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  7. 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time=2019-01-13, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1576678, encodeId=091115e6678d7, content=<a href='/topic/show?id=48fee966468' target=_blank style='color:#2F92EE;'>#置换术#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=55, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=79664, encryptionId=48fee966468, topicName=置换术)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=054816326830, createdName=ms117281293605716, createdTime=Sun Jan 13 08:55:00 CST 2019, time=2019-01-13, status=1, ipAttribution=)]
    2019-01-13 lsj631
  9. 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