Heart：当代先天性心脏病成年人生存数据

2015-11-21 Mechront 译 MedSci原创

目前并没有关于当代伴先天性心脏病成年人的生存相关数据。研究者使用了一种随着年龄增长的生存分析作为主要的时间尺度，估计先天性心脏病成年患者的当代生存率。根据严重程度和病变情况将患者进行分层分析生存率，并于标准人群进行比较。研究数据显示，纳入人群平均年龄37岁，49%为男性。对14 327名患者累积前瞻性随访90 270人年时间内，发生率535例死亡。轻度、中度、重度病变中位生存率分别为84.1 (9

目前并没有关于当代伴先天性心脏病成年人的生存相关数据。研究者使用了一种随着年龄增长的生存分析作为主要的时间尺度，估计先天性心脏病成年患者的当代生存率。根据严重程度和病变情况将患者进行分层分析生存率，并与标准人群进行比较。

研究数据显示，纳入人群平均年龄37岁，49%为男性。对14 327名患者累积前瞻性随访90 270人-年时间内，发生率535例死亡。轻度、中度、重度病变中位生存率分别为84.1(95% CI 81.9 to 87.0)、75.4 (95% CI 72.9 to 79.1)、53.4 (95% CI 49.9 to 60.7)。病变最轻的患者，其生存率与一般人群相比无明显差异，不过中重度患者的生存率明显低于一般人群 (p<0.001)。

该研究提供了先天性心脏病成年人患者的当代生存数据，这可有助于病人咨询、临床干预措施和未来研究的时机选择等。

原始出处：

van der Bom T, Mulder BJ,et al.Contemporary survival of adults with congenital heart disease.Heart. 2015 Nov 5.

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#插入话题

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2016-03-28 thinkibmz_44722603

#生存数据#

58 0
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2015-11-29 三三五五

能不能设计一个小儿的先心数据库？

135 0
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2015-11-23 zhaojie88

#ART#

58 0
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2015-11-23 huirong

#先天性#

50 0
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2015-11-23 slcumt

#HEART#

64 0

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