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JACC:女性冠心病患者的冠脉功能不全与不良预后相关

2019-02-16 不详 网络

目前,近一半疑似有心梗的女性并无冠脉梗阻性疾病(CAD),反倒是冠脉的反应性异常(CR)比较常见。本研究的目的旨在评估和比较有或无CAD女性的CR发生率和远期不良心血管结局(MACE)。本研究纳入了224名有症状的冠心病女性患者,并对其进行了CR检测,经过平均9.7年时间的随访,共有129例不良心血管事件发生,低冠状动脉血流储备是MACE增高的预测因子([HR]: 1.06; 95% [CI]:

目前,近一半疑似有心梗的女性并无冠脉梗阻性疾病(CAD),反倒是冠脉的反应性异常(CR)比较常见。本研究的目的旨在评估和比较有或无CAD女性的CR发生率和远期不良血管结局(MACE)。

本研究纳入了224名有症状的冠心病女性患者,并对其进行了CR检测,经过平均9.7年时间的随访,共有129例不良血管事件发生,低冠状动脉血流储备是MACE增高的预测因子([HR]: 1.06; 95% [CI]: 1.01 - 1.12; p = 0.021),低冠脉血流可增加患者死亡风险(HR: 1.12; 95% CI: 1.01 - 1.24; p = 0.038)和MACE风险(HR: 1.11; 95% CI: 1.03 - 1.20; p = 0.006)。另外,心外膜冠脉硝酸甘油的扩张与临床结局不呈相关性。

研究结果显示,在有临床症状的冠心病女性中,微血管的功能损伤与主要不良心血管结局相关。

原始出处:

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    2019-09-29 hbwxf
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    2019-02-23 jyzxjiangqin

    女性冠心病患者的治疗。

    0

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