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CMAJ:生孩子一定要找妇产科专科医师吗?

2015-09-08 sapphira 译 MedSci原创

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背景:以前的研究表明家庭内科医生和产科医生接生没有什么差别,但那些研究大多是小样本量,而且没有一个做过潜在选择偏倚的调整。我们用计量经济学的方法考虑潜在的混杂因素,对比了研究中的内科家庭医生和产科医生接生的结果。

方法:我们对2006年4月1日至2009年3月31日之间加拿大(除魁北克)所有医院妊娠超过20周、新生儿体重大于500g的生产进行了回顾性的大样本量队列研究,对比了由家庭内科医生和产科医生接生的结果。初期结果是用多变量逻辑回归和工具变量的多变量回归统计院内围产期死亡的风险、产妇死亡率和总的发病率。

结果:390个医院、799823个婴儿、793053个产妇中,共有3600例围产期死亡、14393例产妇患病。对比由内科家庭医生接生和由产科医生接生,根据逻辑回归,围产期死亡的相关风险是0.98(95%置信区间,[CI] 0.85–1.14),母体发病率相关风险是0.81(95% CI 0.70–0.94)。根据工具变量法,这两者分别是0.97(95% CI 0.58–1.64)和1.13(95% CI 0.65–1.95)。

讨论:考虑了所有混杂因素后,我们发现内科家庭医生和产科医生接生的围产期死亡率和严重母体并发症的发生率相似。其他差别尚待研究。

原始出处:

Aubrey-Bassler K, Cullen RM, Simms A, Asghari S, Crane J, Wang PP, Godwin M.Outcomes of deliveries by family physicians or obstetricians: a population-based cohort study using an instrumental variable.CMAJ. 2015 Aug 24. 

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