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阜外医院CHIEF研究1.3万高血压患者调查:降压可明显提升生活质量

2018-09-27 卢芳 中国循环杂志

高血压很多时候是沉默的,有的人就认为这并不影响生活质量,高点就高点没关系,难道使用降压药会对生活质量有干扰?


高血压很多时候是沉默的,有的人就认为这并不影响生活质量,高点就高点没关系,难道使用降压药会对生活质量有干扰?
 
近期阜外医院张宇清、蒋雪丽等对中国高血压综合防治研究(CHIEF)相关数据进行分析发现,降压治疗可改善高血压患者健康相关生活质量,尤其是疼痛或不适、焦虑或抑郁相关维度。
 
另外,在这项研究中,探究的是以氨氯地平为基础的两种联合降压方案:(氨氯地平+复方阿米洛利)和(氨氯地平+替米沙坦)。
 
结果显示,这两种方案也在改善高血压患者健康相关生活质量方面是一样的。
 
既往人群研究表明,即使校正合并症,高血压人群的健康相关生活质量仍然较低,尤其是新诊断为高血压的患者。
 
虽然降压治疗在虚弱、老年人群中引起的低血压症状会影响健康相关生活质量,但服用耐受性良好的一线降压药的患者其生活质量会有所改善。
 
研究者强调,生活质量是高血压管理中非常重要的一部分,临床医生必须平衡考虑降低患者的血管事件和优化生活质量。
 
该研究共纳入CHIEF研究中13,542人,应用使用 EuroQoL 五维问卷(EQ-5D)比较两个降压治疗组患者的健康相关生活质量。

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