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AJG:胰腺炎后糖尿病与2型糖尿病患者死亡和住院的风险的比较

2019-05-20 不详 MedSci原创

胰腺炎患者易出现糖尿病等并发症,因此,本项研究旨在评估胰腺炎后糖尿病(PPDM)患者与2型糖尿病(T2DM)患者的死亡率和住院风险的差异。

背景及目的:
胰腺炎患者易出现糖尿病等并发症,因此,本项研究旨在评估胰腺炎后糖尿病(PPDM)患者与2型糖尿病(T2DM)患者的死亡率和住院风险的差异。

方法:
研究人员利用新西兰胰腺炎和糖尿病出院数据(n = 231943),共鉴定出959例PPDM患者。对于患有PPDM的患者,随机选择10个年龄和性别匹配的患有T2DM的个体进行多变量Cox回归分析。

结果:
10549名总体样本中共发生3867例死亡。PPDM患者的全因死亡率为每***年80.5(95%CI,70.3-90.6),与T2DM患者相比更高(HR,1.13,95%CI,1.00-1.29)。与T2DM相比,PPDM与癌症死亡率(HR,1.44; 95%CI,1.13-1.83),传染病(HR,2.52; 95%CI,1.69-3.77)和肠道疾病(HR,2.56; 95%CI,1.64-4.01)。患有PPDM和T2DM的个体患慢性肺病,中度至重度肾病和传染病的住院风险也显着较高。

结论: 
与患有T2DM的个体相比,患有PPDM的个体具有更高的死亡率和住院风险。

原始出处:

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    2020-04-04 minzju5052
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    2019-05-20 misszhang

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