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JACC:房隔瘤和分流大小对卵圆孔未闭患者卒中复发的影响

2020-05-08 MedSci原创 MedSci原创

在卵圆孔未闭(PFO)的患者中,大分流或房间隔动脉瘤(ASA)的存在被认为是卒中复发的高危因素。本研究的目的旨在评估PFO的大小和ASA对卒中复发的影响。

在卵圆孔未闭(PFO)的患者中,大分流或房间隔动脉瘤(ASA)的存在被认为是卒中复发的高危因素。本研究的目的旨在评估PFO的大小和ASA对卒中复发的影响。

本研究纳入分析了来自2个临床试验的898名PFO患者(平均年龄45.3岁),其中19.8%患者为大型PFO伴ASA,7.9%患者为非大型PFO伴ASA,44.2%患者为大型PFO不伴ASA,28.1%患者为非大型PFO不伴ASA。经过超过3.8年时间的随访,47名患者发生复发性卒中,PFO的大小与卒中复发的相关性存在异质性。在一个包括年龄、高血压、抗血栓治疗和PFO解剖的模型中,ASA与复发性卒中独立相关,而大型PFO不呈相关性。

研究结果显示,在卵圆孔未闭伴卒中的患者中,房隔瘤是比分流大小更重要的复发性卒中预测因素。

原始出处:

Guillaume T et al.Atrial Septal Aneurysm, Shunt Size, and Recurrent Stroke Risk in Patients With Patent Foramen Ovale.JACC.2020 May.

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    2021-01-28 hbwxf
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    2020-05-09 健健

    卒中虽然是临床上常见病,溶栓,取栓等血管内治疗也很成熟,但是仍然有很多未知问题有待认知!

    0

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