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AM J CRIT CARE:导尿管相关性菌血症的危险因素

2017-02-14 MedSci MedSci原创

导管相关性细菌尿症中有0.4%至4.0%的患者继发菌血症。直接归因死亡率为12.7%。近期,一项旨在研究导管相关性菌尿导致菌血症的危险因素的文章发表在杂志AM J CRIT CARE上。研究数据来自一个大型电子临床和行政数据库,收集7年时间住院病人的相关数据。将与导管相关细菌尿和菌血症的患者数据与具有导管相关性菌尿但无菌血症的患者数据进行比较,匹配入院日期加或减30天。在7天内尿培养和血培养发现相

导管相关性细菌尿症中有0.4%至4.0%的患者继发菌血症。直接归因死亡率为12.7%。


近期,一项旨在研究导管相关性菌尿导致菌血症的危险因素的文章发表在杂志AM J CRIT CARE上。

研究数据来自一个大型电子临床和行政数据库,收集7年时间住院病人的相关数据。将与导管相关细菌尿和菌血症的患者数据与具有导管相关性菌尿但无菌血症的患者数据进行比较,匹配入院日期加或减30天。在7天内尿培养和血培养发现相同病原体定义为导管相关的菌尿症和菌血症。使用多变量条件逻辑回归分析确定菌血症的独立危险因素。

研究结果显示:样本量由158例病例组和474例对照组构成。菌血症的独立预测因素是男性(优势比,2.76),用免疫抑制剂治疗(优势比,1.68),尿路手术(优势比,2.70)以及在细菌尿发生后仍保留导尿管(优势比,2.75)。与其他泌尿道病原体患者相比,肠球菌菌尿患者有一般的可能性发生菌血症(优势比为0.46)。每住院一天,继发性菌血症的发生率增加2%(95%CI,1.01-1.04);患者年龄每增加一岁(95%CI,0.97-0.99),继发性菌血症的发生率减少1%。

此研究结果增加了关于在导管相关细菌尿之后仍留置导管的患者中,菌血症的风险增加的新证据,并且证实了先前鉴定的风险因素。

原始出处:
Conway LJ, Liu J, Harris AD, Larson EL. Risk Factors for Bacteremia in Patients With Urinary Catheter-Associated Bacteriuria. Am J Crit Care. 2016 Dec;26(1):43-52.

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  2. [GetPortalCommentsPageByObjectIdResponse(id=1837218, encodeId=b25c183e2181f, content=<a href='/topic/show?id=3f34e253206' target=_blank style='color:#2F92EE;'>#相关性#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=67, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=72532, encryptionId=3f34e253206, topicName=相关性)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=a9de34, createdName=shenxlcyp, createdTime=Sat Jun 03 21:54:00 CST 2017, time=2017-06-03, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=180112, encodeId=aedf18011289, content=文章的想法有新意,值得学习和借鉴,以后还会多多关注, beContent=null, objectType=article, channel=null, level=null, likeNumber=102, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=82351961337, createdName=1e137bdcm70(暂无匿称), createdTime=Wed Mar 15 15:47:21 CST 2017, time=2017-03-15, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1303927, encodeId=626a130392e73, content=<a href='/topic/show?id=d1a0880e7c8' target=_blank style='color:#2F92EE;'>#菌血症#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=55, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=88077, encryptionId=d1a0880e7c8, topicName=菌血症)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=e5bc315, createdName=Tommy1949, createdTime=Thu Feb 16 06:54:00 CST 2017, time=2017-02-16, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1545598, encodeId=cc1f15455983b, content=<a href='/topic/show?id=3afb466990c' target=_blank style='color:#2F92EE;'>#导尿管#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=76, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=46699, encryptionId=3afb466990c, topicName=导尿管)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=e39a13780945, createdName=12498b3em12(暂无昵称), createdTime=Thu Feb 16 06:54:00 CST 2017, time=2017-02-16, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=176317, encodeId=cfc31e631727, content=很好,不错,以后会多学习, beContent=null, objectType=article, channel=null, level=null, likeNumber=77, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=fd301464769, createdName=Albert Wu, createdTime=Wed Feb 15 20:46:19 CST 2017, time=2017-02-15, status=1, ipAttribution=)]
    2017-03-15 1e137bdcm70(暂无匿称)

    文章的想法有新意,值得学习和借鉴,以后还会多多关注

    0

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  5. [GetPortalCommentsPageByObjectIdResponse(id=1837218, encodeId=b25c183e2181f, content=<a href='/topic/show?id=3f34e253206' target=_blank style='color:#2F92EE;'>#相关性#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=67, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=72532, encryptionId=3f34e253206, topicName=相关性)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=a9de34, createdName=shenxlcyp, createdTime=Sat Jun 03 21:54:00 CST 2017, time=2017-06-03, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=180112, encodeId=aedf18011289, content=文章的想法有新意,值得学习和借鉴,以后还会多多关注, beContent=null, objectType=article, channel=null, level=null, likeNumber=102, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=82351961337, createdName=1e137bdcm70(暂无匿称), createdTime=Wed Mar 15 15:47:21 CST 2017, time=2017-03-15, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1303927, encodeId=626a130392e73, content=<a href='/topic/show?id=d1a0880e7c8' target=_blank style='color:#2F92EE;'>#菌血症#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=55, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=88077, encryptionId=d1a0880e7c8, topicName=菌血症)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=e5bc315, createdName=Tommy1949, createdTime=Thu Feb 16 06:54:00 CST 2017, time=2017-02-16, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1545598, encodeId=cc1f15455983b, content=<a href='/topic/show?id=3afb466990c' target=_blank style='color:#2F92EE;'>#导尿管#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=76, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=46699, encryptionId=3afb466990c, topicName=导尿管)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=e39a13780945, createdName=12498b3em12(暂无昵称), createdTime=Thu Feb 16 06:54:00 CST 2017, time=2017-02-16, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=176317, encodeId=cfc31e631727, content=很好,不错,以后会多学习, beContent=null, objectType=article, channel=null, level=null, likeNumber=77, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=fd301464769, createdName=Albert Wu, createdTime=Wed Feb 15 20:46:19 CST 2017, time=2017-02-15, status=1, ipAttribution=)]
    2017-02-15 Albert Wu

    很好,不错,以后会多学习

    0

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