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盘点那些年,被误诊的5种狼疮症状~你中招没?

2018-07-05 佚名 健风源

系统性红斑狼疮,是一种发作和缓解交替发生的慢性疾病。由抗原和抗体免疫反应形成的血管炎,造成不同部位的组织损伤,产生相应的临床表现。因为全身各器官都有血液供应,血管受累必定会有损伤,所以有血管的部位均可受累,产生不同的临床表现。

系统性红斑狼疮,是一种发作和缓解交替发生的慢性疾病。由抗原和抗体免疫反应形成的血管炎,造成不同部位的组织损伤,产生相应的临床表现。因为全身各器官都有血液供应,血管受累必定会有损伤,所以有血管的部位均可受累,产生不同的临床表现。

系统性红斑狼疮是一种全身性疾病,皮肤、肌肉、骨骼、心、肺、肝、脾、肾、脑、眼、耳、鼻、牙齿、头发均可出现病变,只是不同的病期有不同的临床表现罢了。因个人的起病方式不一,器官受累的先后不一,所以临床表现多种多样,极易误诊。

六个早期典型信号

在疾病早期,患者可能会出现发热、乏力、食欲减退、全身乏力、关节肿痛、肌肉酸痛、体重减轻等一般症状。

其中,最为典型的早期信号就要数下列这6个了:

高热,关节痛,指端红疹和双手、足遇凉后变白或变紫;

或反复口腔溃疡,浅表淋巴结肿大,经期出血不止;

或皮肤紫癜,贫血,白细胞、血小板数下降;

或精神症状,头痛,幻觉,幻听,木僵状态;

顽固性腹泻,呕吐,黄疸;

心悸气短,不能平卧,出现胸水、心包积液等。

以上症状均可在许多疾病中出现,因此加大了诊断的难度,常常误诊为其他疾病。

五种症状易被误诊

关节痛误诊为类风湿关节炎,

蛋白尿误诊为肾炎,

胸水误诊为结核性胸膜炎。

贫血、白细胞、血小板减少误诊为再生障碍性贫血

黄疸误诊为肝炎,发热、淋巴结肿大误诊为淋巴瘤

神经症状误诊为精神病

针对那些出现不明原因发热并伴有多个系统损伤的女性,一定要优先排查系统性红斑狼疮的可能性。

四招降低误诊率

1. 留心早期症状

了解SLE的早期、多发症状非常重要。关节症状是sle早期和最常见表现,发生率达90%以上。建议对关节症状应作风湿性关节炎、类风湿性关节炎及sle相关检查,以免误诊或漏诊。

2.排查狼疮肾病

Sle肾损害的发生率约占75%,可在疾病的任何阶段,且其病变及临床表现复杂多样。所以应精良排除继发性肾小球病,才能确立为原发性。

3. 观察育龄妇女

当育龄妇女出现关节痛或关节炎、肾损害、血细胞减少,病因未明或治疗效果欠佳时,应提高系统性红斑狼疮的警惕性,做有关免疫学方面的检查,注意观察和随诊。

4. 男性更需警惕

提高对男性sle的警惕性,不能因为少见而忽略。男性患者以肾损害多见。对于有肾炎、肾病的男性,即使暂时没有多系统损害,没有出现典型皮疹,也应警惕sle的可能性。

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    2018-08-07 明崖

    学习了,有用的研究

    0

  2. [GetPortalCommentsPageByObjectIdResponse(id=336991, encodeId=bd98336991c9, content=学习了,有用的研究, beContent=null, objectType=article, channel=null, level=null, likeNumber=126, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=73441710184, createdName=明崖, createdTime=Tue Aug 07 07:46:17 CST 2018, time=2018-08-07, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=330640, encodeId=9d6c33064048, content=学习一下, beContent=null, objectType=article, channel=null, level=null, likeNumber=100, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/jW482SpianMayicTRbRZ5RzaiabIFicf63hKvVMjL6aJlx4yX4UcXmzX9DyibCRcicq0QtCRWMaQKh8MYjE1D3EKUBopgiaGWYuqbeR/0, createdBy=0c2b1999806, createdName=三生有幸9135, createdTime=Tue Jul 10 17:28:00 CST 2018, time=2018-07-10, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=330448, encodeId=476033044849, content=学习一下, beContent=null, objectType=article, channel=null, level=null, likeNumber=1, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/jW482SpianMayicTRbRZ5RzaiabIFicf63hKvVMjL6aJlx4yX4UcXmzX9DyibCRcicq0QtCRWMaQKh8MYjE1D3EKUBopgiaGWYuqbeR/0, createdBy=0c2b1999806, createdName=三生有幸9135, createdTime=Mon Jul 09 22:17:50 CST 2018, time=2018-07-09, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=330018, encodeId=24d733001881, content=学习一下, beContent=null, objectType=article, channel=null, level=null, likeNumber=150, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/jW482SpianMayicTRbRZ5RzaiabIFicf63hKvVMjL6aJlx4yX4UcXmzX9DyibCRcicq0QtCRWMaQKh8MYjE1D3EKUBopgiaGWYuqbeR/0, createdBy=0c2b1999806, createdName=三生有幸9135, createdTime=Sat Jul 07 15:38:37 CST 2018, time=2018-07-07, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=330015, encodeId=fe70330015ad, content=学习一下, beContent=null, objectType=article, channel=null, level=null, likeNumber=127, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/jW482SpianMayicTRbRZ5RzaiabIFicf63hKvVMjL6aJlx4yX4UcXmzX9DyibCRcicq0QtCRWMaQKh8MYjE1D3EKUBopgiaGWYuqbeR/0, createdBy=0c2b1999806, createdName=三生有幸9135, createdTime=Sat Jul 07 15:36:56 CST 2018, time=2018-07-07, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1387277, encodeId=d834138e27759, content=<a href='/topic/show?id=8a3a6814425' target=_blank style='color:#2F92EE;'>#狼疮#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=128, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=68144, encryptionId=8a3a6814425, topicName=狼疮)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=7a6e2500005, createdName=sunrural_42825357, createdTime=Sat Jul 07 02:05:00 CST 2018, time=2018-07-07, status=1, ipAttribution=)]
    2018-07-10 三生有幸9135

    学习一下

    0

  3. [GetPortalCommentsPageByObjectIdResponse(id=336991, encodeId=bd98336991c9, content=学习了,有用的研究, beContent=null, objectType=article, channel=null, level=null, likeNumber=126, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=73441710184, createdName=明崖, createdTime=Tue Aug 07 07:46:17 CST 2018, time=2018-08-07, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=330640, encodeId=9d6c33064048, content=学习一下, beContent=null, objectType=article, channel=null, level=null, likeNumber=100, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/jW482SpianMayicTRbRZ5RzaiabIFicf63hKvVMjL6aJlx4yX4UcXmzX9DyibCRcicq0QtCRWMaQKh8MYjE1D3EKUBopgiaGWYuqbeR/0, createdBy=0c2b1999806, createdName=三生有幸9135, createdTime=Tue Jul 10 17:28:00 CST 2018, time=2018-07-10, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=330448, encodeId=476033044849, content=学习一下, beContent=null, objectType=article, channel=null, level=null, likeNumber=1, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/jW482SpianMayicTRbRZ5RzaiabIFicf63hKvVMjL6aJlx4yX4UcXmzX9DyibCRcicq0QtCRWMaQKh8MYjE1D3EKUBopgiaGWYuqbeR/0, createdBy=0c2b1999806, createdName=三生有幸9135, createdTime=Mon Jul 09 22:17:50 CST 2018, time=2018-07-09, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=330018, encodeId=24d733001881, content=学习一下, beContent=null, objectType=article, channel=null, level=null, likeNumber=150, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/jW482SpianMayicTRbRZ5RzaiabIFicf63hKvVMjL6aJlx4yX4UcXmzX9DyibCRcicq0QtCRWMaQKh8MYjE1D3EKUBopgiaGWYuqbeR/0, createdBy=0c2b1999806, createdName=三生有幸9135, createdTime=Sat Jul 07 15:38:37 CST 2018, time=2018-07-07, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=330015, encodeId=fe70330015ad, content=学习一下, beContent=null, objectType=article, channel=null, level=null, likeNumber=127, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/jW482SpianMayicTRbRZ5RzaiabIFicf63hKvVMjL6aJlx4yX4UcXmzX9DyibCRcicq0QtCRWMaQKh8MYjE1D3EKUBopgiaGWYuqbeR/0, createdBy=0c2b1999806, createdName=三生有幸9135, createdTime=Sat Jul 07 15:36:56 CST 2018, time=2018-07-07, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1387277, encodeId=d834138e27759, content=<a href='/topic/show?id=8a3a6814425' target=_blank style='color:#2F92EE;'>#狼疮#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=128, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=68144, encryptionId=8a3a6814425, topicName=狼疮)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=7a6e2500005, createdName=sunrural_42825357, createdTime=Sat Jul 07 02:05:00 CST 2018, time=2018-07-07, status=1, ipAttribution=)]
    2018-07-09 三生有幸9135

    学习一下

    0

  4. [GetPortalCommentsPageByObjectIdResponse(id=336991, encodeId=bd98336991c9, content=学习了,有用的研究, beContent=null, objectType=article, channel=null, level=null, likeNumber=126, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=73441710184, createdName=明崖, createdTime=Tue Aug 07 07:46:17 CST 2018, time=2018-08-07, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=330640, encodeId=9d6c33064048, content=学习一下, beContent=null, objectType=article, channel=null, level=null, likeNumber=100, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/jW482SpianMayicTRbRZ5RzaiabIFicf63hKvVMjL6aJlx4yX4UcXmzX9DyibCRcicq0QtCRWMaQKh8MYjE1D3EKUBopgiaGWYuqbeR/0, createdBy=0c2b1999806, createdName=三生有幸9135, createdTime=Tue Jul 10 17:28:00 CST 2018, time=2018-07-10, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=330448, encodeId=476033044849, content=学习一下, beContent=null, objectType=article, channel=null, level=null, likeNumber=1, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/jW482SpianMayicTRbRZ5RzaiabIFicf63hKvVMjL6aJlx4yX4UcXmzX9DyibCRcicq0QtCRWMaQKh8MYjE1D3EKUBopgiaGWYuqbeR/0, createdBy=0c2b1999806, createdName=三生有幸9135, createdTime=Mon Jul 09 22:17:50 CST 2018, time=2018-07-09, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=330018, encodeId=24d733001881, content=学习一下, beContent=null, objectType=article, channel=null, level=null, likeNumber=150, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/jW482SpianMayicTRbRZ5RzaiabIFicf63hKvVMjL6aJlx4yX4UcXmzX9DyibCRcicq0QtCRWMaQKh8MYjE1D3EKUBopgiaGWYuqbeR/0, createdBy=0c2b1999806, createdName=三生有幸9135, createdTime=Sat Jul 07 15:38:37 CST 2018, time=2018-07-07, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=330015, encodeId=fe70330015ad, content=学习一下, beContent=null, objectType=article, channel=null, level=null, likeNumber=127, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/jW482SpianMayicTRbRZ5RzaiabIFicf63hKvVMjL6aJlx4yX4UcXmzX9DyibCRcicq0QtCRWMaQKh8MYjE1D3EKUBopgiaGWYuqbeR/0, createdBy=0c2b1999806, createdName=三生有幸9135, createdTime=Sat Jul 07 15:36:56 CST 2018, time=2018-07-07, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1387277, encodeId=d834138e27759, content=<a href='/topic/show?id=8a3a6814425' target=_blank style='color:#2F92EE;'>#狼疮#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=128, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=68144, encryptionId=8a3a6814425, topicName=狼疮)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=7a6e2500005, createdName=sunrural_42825357, createdTime=Sat Jul 07 02:05:00 CST 2018, time=2018-07-07, status=1, ipAttribution=)]
    2018-07-07 三生有幸9135

    学习一下

    0

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    2018-07-07 三生有幸9135

    学习一下

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