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J Rheumatol:手部骨关节炎患者的健康相关生活质量

2019-12-15 xiangting MedSci原创

在一般人群和医院患者中,手部骨关节炎与躯体HRQoL降低有关,而与精神HRQoL无关。

这项研究旨在探讨普通人群和风湿病门诊患者中,手部骨关节炎、手部合并膝部骨关节炎与健康相关生活质量(HRQoL)的关联。

在基于人群的NEO研究中,参与者来自莱顿大片地区。在HOSTAS研究中,从一家位于莱顿的医院招募被风湿病医师诊断为手部骨关节炎的患者。在这两个队列中,根据ACR临床标准定义手部和膝部骨关节炎。在NEO中,记录自我报告的OA医院专家咨询。躯体和精神HRQoL使用SF-36标准化得分进行评估。使用线性回归分析相关性,并根据年龄、性别、教育程度、种族和BMI进行调整。

6,334NEO参与者中,分别有8%和4为单独手部骨关节炎以及手部合并膝部骨关节炎。538HOSTAS患者中,分别为57%和32%。在NEO中,与无骨关节炎相比,单独手部骨关节炎和手部合并膝部骨关节炎与躯体成分(PCS)评分较低相关(平均差异(95CI-2.4-3.6; -1.3)和-7.7-9.3; -6.2))。咨询专家与PCS分数低相关。在HOSTAS队列中,平均PCS得分低于正常值(手部骨关节炎和合并骨关节炎分别为-3.5-7.9)。在这两个队列中,精神HRQoL临床上均无相关性。

在一般人群和医院患者中,手部骨关节炎与躯体HRQoL降低有关,而与精神HRQoL无关。在医院治疗中,躯体HRQoL进一步降低,并可能合并膝部骨关节炎。

原始出处:

Marieke Loef. Health-related quality of life in patients with hand osteoarthritis from the general population and the outpatient clinic. J Rheumatol. December 2019.

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    2020-02-25 lisa438
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    2019-12-17 lmm397
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