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Gut:日常饮食结构对肠易激患者肠道菌群的影响

2017-04-21 zhangfan MedSci原创

低聚糖、双糖、单糖和多元醇餐饮食通过改变肠道菌群分布对粪便细菌有显着影响

肠道细菌对人们健康的重要性毋庸置疑,但每天的饮食对肠道细菌的影响尚不是十分清楚。近日,研究人员对不同的饮食结构对肠道细菌的影响开展研究。

研究招募了67名肠易激综合征患者随机进入对照组(n=34)或低聚糖、双糖、单糖和多元醇餐饮组(FODMAPs, n=33),研究持续4周。分别在试验开始前(基线)后纪录粪便样本和IBS症状严重度评分(IBS-SSS)。粪便菌群失调试验(GA-map Dysbiosis Test) 用于评估细菌组成。试验认定IBS-SSS评分减少50分以上视为有应答。

研究发现,FODMAPs组存在应答,但对照组无变化;试验开始前粪便样本,FODMAPs组与对照组差别显着;相比于FODMAPs组有应答患者,FODMAPs组无应答患者细菌丰度在饮食干预后显着提高;有42%的FODMAPs组患者粪便菌群失调试验得分提高,对照组有33%的患者得分降低,FODMAPs组无应答患者较有应答患者的得分较基线变化大。对照组患者菌群改变不显著,FODMAPs组双歧杆菌和放线菌数量减少。

研究表明低FODMAP饮食通过改变肠道菌群分布对粪便细菌有显著影响。

原文出处:


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    2017-04-26 1e145228m78(暂无匿称)

    学习了,谢谢作者分享!

    0

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  3. [GetPortalCommentsPageByObjectIdResponse(id=190795, encodeId=0682190e95e9, content=学习了,谢谢作者分享!, beContent=null, objectType=article, channel=null, level=null, likeNumber=97, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/mONcle9pic3xJXLtMtt5B40XXuPjn9xn1rBhrM6fHLkX1hI86ZoWoPJkgDkZuJNKkBfBHOcRd1fAdezg7JlHNOokohdAp3WkI/0, createdBy=32c81964262, createdName=1e145228m78(暂无匿称), createdTime=Wed Apr 26 14:59:52 CST 2017, time=2017-04-26, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1392242, encodeId=187613922428d, content=<a href='/topic/show?id=223081e33b6' target=_blank style='color:#2F92EE;'>#肠道菌#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=60, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=81733, encryptionId=223081e33b6, topicName=肠道菌)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=aa292500107, createdName=1249897bm37(暂无昵称), createdTime=Sun Apr 23 01:08:00 CST 2017, time=2017-04-23, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=189349, encodeId=49d6189349da, content=谢谢分享,学习了, beContent=null, objectType=article, channel=null, level=null, likeNumber=78, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/NUyjXTCJjo6Nx0VGA4QMDzOP8oAgnV4h51EjSfehJ9QxyiaSmw8PB56BhY8KXFSxHCibXrzcy4abrzSibXQPxJ9kzrLcJyhhB8a/0, createdBy=1d3b1672603, createdName=明月清辉, createdTime=Fri Apr 21 12:07:08 CST 2017, time=2017-04-21, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=189341, encodeId=85ba1893415d, content=涨知识,学习了, beContent=null, objectType=article, channel=null, level=null, likeNumber=88, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://img.medsci.cn/20220115/46bcf39c32de4aa6b45c5f9d66c8ee77/6cb4a20c55bb4b7691122f47747bfca2.jpg, createdBy=9dad1662329, createdName=1ddf0692m34(暂无匿称), createdTime=Fri Apr 21 10:50:40 CST 2017, time=2017-04-21, status=1, ipAttribution=)]
    2017-04-21 明月清辉

    谢谢分享,学习了

    0

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    2017-04-21 1ddf0692m34(暂无匿称)

    涨知识,学习了

    0

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