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JACC:心脏磁共振可无创监测肺血管阻力变化

2013-08-19 高晓方 译 cmt

西班牙一项研究表明,心脏磁共振(CMR)可对肺动脉高压(PH)患者的肺血管阻力(PVR)急性和慢性变化实施无创监测。论文8月在线发表于《美国心脏病学会杂志》(J Am Coll Cardiol)。 此项研究利用实验用猪评估了CMR监测PVR急性和远期变化的能力。通过急性肺栓塞使PVR出现急剧升高,并通过慢性PH模型系列评估PVR变化。利用飘浮导管同时实施血液动力学评

西班牙一项研究表明,心脏磁共振(CMR)可对肺动脉高压(PH)患者的肺血管阻力(PVR)急性和慢性变化实施无创监测。论文8月在线发表于《美国心脏病学会杂志》(J Am Coll Cardiol)。

此项研究利用实验用猪评估了CMR监测PVR急性和远期变化的能力。通过急性肺栓塞使PVR出现急剧升高,并通过慢性PH模型系列评估PVR变化。利用飘浮导管同时实施血液动力学评估。通过相衬成像对肺动脉主干平均流速进行定量。

结果显示,肺动脉流速变化与肺栓塞诱导的PVR急性变化(r=-0.92)、慢性PH中系列PVR波动(r=-0.89)以及血管舒张试验中PVR急性降低(r=-0.89)均呈显著负相关(P≤0.01)。CMR评估PVR与有创PVR具有充分一致性,并且两种指数变化显著相关(r=0.86,P<0.01)。

原始出处:

Ana García-Álvarez; Leticia Fernández-Friera; José Manuel García-Ruiz; Mario Nuño-Ayala; Daniel Pereda; Rodrigo Fernández-Jiménez; Gabriela Guzmán; Damián Sanchez-Quintana; Angel Alberich-Bayarri; David Pastor-Escuredo; David Sanz-Rosa; Jaime García-Prieto, BS; Jesús G. Mirelis; Gonzalo Pizarro; Luis Jesús Jimenez-Borreguero; Valentín Fuster; Javier Sanz; Borja Ibáñez.Noninvasive Monitoring of Serial Changes in Pulmonary Vascular Resistance and Acute Vasodilator Testing using Cardiac Magnetic Resonance ONLINE FIRST.J Am Coll Cardiol. 2013;():. doi:10.1016/j.jacc.2013.07.037

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    2014-01-06 hbwxf
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