2011ACCF/AHA/ESC/WHF 对心肌梗死分型和心血管死亡危险的通用定义

中文标题：

2011ACCF/AHA/ESC/WHF 对心肌梗死分型和心血管死亡危险的通用定义

英文标题：

2011ACCF/AHA/ESC/WHF Universal Definition of Myocardial Infarction Classification System and the Risk of Cardiovascular Death: Observations from the TRITON-TIMI 38 Trial

发布机构：

美国心脏病学会基金会

发布日期：

2011-12-23

简要介绍：

The epidemiology of myocardial infarction (MI) has changed in the era of newer, more sensitive biomarker assays and the new Univer sal Definition of MI Clinical Classification system.The ability to detect myocardial injury at increasingly lower concentrations of cardiac troponin has raised uncertainty for some clinicians as to the prognostic implications of hese forms of infarction.Moreover, some have questioned the significance of MIs occurring in specific clinical contexts such as after percutaneous intervention (PCI) or when secondary to increased myocardial oxygen demand.This uncertainty poses a challenge to clinicians balancing the risks of therapies aimed at preventing these events.In addition, researchers have grappled with refining criteria for recurrent MI, particularly peri-procedural events, in the design of clinical trials in acute coronary syndromes (ACS).We previously described the epidemiology of new (or recurrent) MI after ACS using the Universal Definition of MI Classification system to characterize MI subtypes (e.g. Type 1 spontaneous, Type 2 demand) and the effect of the novel thienopyridine, prasugrel, across each class of MI.However, the prognostic implications of each MI type have not been adequately explored. Therefore, we assessed the risk of cardiovascular (CV) death after a new (or recurrent) MI in this setting, including according to the clinical subtypes defined by the Universal Definition of MI Classification System.