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中国儿童及青少年横纹肌肉瘤诊疗建议(CCCG－RMS－2016)

2017-10-20 中国抗癌协会小儿肿瘤专业委员会 中华儿科杂志,2017,55(10) :724-728.

横纹肌肉瘤(rhabdomyosarcoma，RMS)是儿童期最常见的软组织肿瘤，占儿童肿瘤的6.5%左右。原发部位以头颈部多发，其次为躯干、四肢及泌尿生殖系统。RMS对化疗、放疗敏感，但单一治疗效果差，需要肿瘤内科、外科、放疗等多学科联合的综合治疗。美国儿童横纹肌肉瘤协作组(Intergroup RMS Study Group，IRSG)和欧洲儿童软组织肉瘤研究组(European Pediat

中文标题：

中国儿童及青少年横纹肌肉瘤诊疗建议(CCCG－RMS－2016)

发布机构：

中国抗癌协会小儿肿瘤专业委员会

发布日期：

2017-10-20

简要介绍：

横纹肌肉瘤(rhabdomyosarcoma，RMS)是儿童期最常见的软组织肿瘤，占儿童肿瘤的6.5%左右。原发部位以头颈部多发，其次为躯干、四肢及泌尿生殖系统。RMS对化疗、放疗敏感，但单一治疗效果差，需要肿瘤内科、外科、放疗等多学科联合的综合治疗。美国儿童横纹肌肉瘤协作组(Intergroup RMS Study Group，IRSG)和欧洲儿童软组织肉瘤研究组(European Pediatric soft tissue sarcomas study group，EpSSG)等较大儿童肿瘤研究组经过20余年的临床研究，并根据年龄、肿瘤大小、病理、临床分期，将RMS分为低、中和高危3组，进行分层和综合治疗，以不断优化化疗方案，进一步改善预后，使得RMS疗效逐年提高。2013年9月，经中国小儿肿瘤专业委员会(Chinese Children Cancer Group, CCCG)批准，建立了中国儿童及青少年RMS协作组。协作组首先回顾性分析国内5家较大儿童医院系统治疗并随访的RMS患儿诊治效果，临床研究显示：患儿总体生存率偏差，原因可能与诊断时发生远处转移患儿多、治疗方法单一以及管理不规范有关。因此，根据以上研究结果，结合IRSG和EpSSG研究成果制定了本诊疗建议。

 

拓展指南：与横纹肌肉瘤相关指南：

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中国儿童及青少年横纹肌肉瘤诊疗建议(CCCG－RMS－2016)
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    2020-12-02 lixiangyin5101_17573246

    不错的参考规范

    0

  2. [GetPortalCommentsPageByObjectIdResponse(id=904407, encodeId=e43690440e34, content=不错的参考规范, beContent=null, objectType=guider, channel=null, level=null, likeNumber=108, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://img.medsci.cn/20201202/13cd4d4e7ba441828e6c52e1b620d027/a7514941584a4656961851bd67ef4fbd.jpg, createdBy=19ee2419640, createdName=lixiangyin5101_17573246, createdTime=Wed Dec 02 21:41:32 CST 2020, time=2020-12-02, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=257381, encodeId=ba9025e381b6, content=阅读.谢谢分享, beContent=null, objectType=guider, channel=null, level=null, likeNumber=147, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://cdnapi.center.medsci.cn/medsci/head/2017/04/21/72142930668371951a41ef4ea4b233e6.jpg, createdBy=dcbc1715228, createdName=刘煜, createdTime=Tue Oct 31 06:33:26 CST 2017, time=2017-10-31, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=257215, encodeId=2b5e25e21555, content=很好的文章.谢谢分享, beContent=null, objectType=guider, channel=null, level=null, likeNumber=124, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/Q3auHgzwzM4o2XVpJ6449yqDsjibydI5HnJ8MibGxNn4HZiaZib0bdfibbwoz3KQrIyN9AGxq36ZlZRNicYlPfOOWMtwgsajY6mGNFiaPclFdowjD0/0, createdBy=97bd1338592, createdName=清风拂面, createdTime=Mon Oct 30 12:34:34 CST 2017, time=2017-10-30, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=257182, encodeId=7b8d25e182b9, content=学习学习.了解了解, beContent=null, objectType=guider, channel=null, level=null, likeNumber=127, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=93f31631454, createdName=1dd8c52fm63(暂无匿称), createdTime=Mon Oct 30 08:48:21 CST 2017, time=2017-10-30, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=257114, encodeId=2be425e1144f, content=好好好好好好好好, beContent=null, objectType=guider, channel=null, level=null, likeNumber=133, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://cdnapi.center.medsci.cn/medsci/head/2017/08/29/bbc5cc0eed9b8d17623d2fd49dbdf19a.jpg, createdBy=79522135794, createdName=yjs木玉, createdTime=Mon Oct 30 06:03:17 CST 2017, time=2017-10-30, status=1, ipAttribution=)]
    2017-10-31 刘煜

    阅读.谢谢分享

    0

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    2017-10-30 清风拂面

    很好的文章.谢谢分享

    0

  4. [GetPortalCommentsPageByObjectIdResponse(id=904407, encodeId=e43690440e34, content=不错的参考规范, beContent=null, objectType=guider, channel=null, level=null, likeNumber=108, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://img.medsci.cn/20201202/13cd4d4e7ba441828e6c52e1b620d027/a7514941584a4656961851bd67ef4fbd.jpg, createdBy=19ee2419640, createdName=lixiangyin5101_17573246, createdTime=Wed Dec 02 21:41:32 CST 2020, time=2020-12-02, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=257381, encodeId=ba9025e381b6, content=阅读.谢谢分享, beContent=null, objectType=guider, channel=null, level=null, likeNumber=147, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://cdnapi.center.medsci.cn/medsci/head/2017/04/21/72142930668371951a41ef4ea4b233e6.jpg, createdBy=dcbc1715228, createdName=刘煜, createdTime=Tue Oct 31 06:33:26 CST 2017, time=2017-10-31, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=257215, encodeId=2b5e25e21555, content=很好的文章.谢谢分享, beContent=null, objectType=guider, channel=null, level=null, likeNumber=124, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/Q3auHgzwzM4o2XVpJ6449yqDsjibydI5HnJ8MibGxNn4HZiaZib0bdfibbwoz3KQrIyN9AGxq36ZlZRNicYlPfOOWMtwgsajY6mGNFiaPclFdowjD0/0, createdBy=97bd1338592, createdName=清风拂面, createdTime=Mon Oct 30 12:34:34 CST 2017, time=2017-10-30, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=257182, encodeId=7b8d25e182b9, content=学习学习.了解了解, beContent=null, objectType=guider, channel=null, level=null, likeNumber=127, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=93f31631454, createdName=1dd8c52fm63(暂无匿称), createdTime=Mon Oct 30 08:48:21 CST 2017, time=2017-10-30, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=257114, encodeId=2be425e1144f, content=好好好好好好好好, beContent=null, objectType=guider, channel=null, level=null, likeNumber=133, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://cdnapi.center.medsci.cn/medsci/head/2017/08/29/bbc5cc0eed9b8d17623d2fd49dbdf19a.jpg, createdBy=79522135794, createdName=yjs木玉, createdTime=Mon Oct 30 06:03:17 CST 2017, time=2017-10-30, status=1, ipAttribution=)]
    2017-10-30 1dd8c52fm63(暂无匿称)

    学习学习.了解了解

    0

  5. [GetPortalCommentsPageByObjectIdResponse(id=904407, encodeId=e43690440e34, content=不错的参考规范, beContent=null, objectType=guider, channel=null, level=null, likeNumber=108, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://img.medsci.cn/20201202/13cd4d4e7ba441828e6c52e1b620d027/a7514941584a4656961851bd67ef4fbd.jpg, createdBy=19ee2419640, createdName=lixiangyin5101_17573246, createdTime=Wed Dec 02 21:41:32 CST 2020, time=2020-12-02, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=257381, encodeId=ba9025e381b6, content=阅读.谢谢分享, beContent=null, objectType=guider, channel=null, level=null, likeNumber=147, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://cdnapi.center.medsci.cn/medsci/head/2017/04/21/72142930668371951a41ef4ea4b233e6.jpg, createdBy=dcbc1715228, createdName=刘煜, createdTime=Tue Oct 31 06:33:26 CST 2017, time=2017-10-31, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=257215, encodeId=2b5e25e21555, content=很好的文章.谢谢分享, beContent=null, objectType=guider, channel=null, level=null, likeNumber=124, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/Q3auHgzwzM4o2XVpJ6449yqDsjibydI5HnJ8MibGxNn4HZiaZib0bdfibbwoz3KQrIyN9AGxq36ZlZRNicYlPfOOWMtwgsajY6mGNFiaPclFdowjD0/0, createdBy=97bd1338592, createdName=清风拂面, createdTime=Mon Oct 30 12:34:34 CST 2017, time=2017-10-30, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=257182, encodeId=7b8d25e182b9, content=学习学习.了解了解, beContent=null, objectType=guider, channel=null, level=null, likeNumber=127, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=93f31631454, createdName=1dd8c52fm63(暂无匿称), createdTime=Mon Oct 30 08:48:21 CST 2017, time=2017-10-30, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=257114, encodeId=2be425e1144f, content=好好好好好好好好, beContent=null, objectType=guider, channel=null, level=null, likeNumber=133, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://cdnapi.center.medsci.cn/medsci/head/2017/08/29/bbc5cc0eed9b8d17623d2fd49dbdf19a.jpg, createdBy=79522135794, createdName=yjs木玉, createdTime=Mon Oct 30 06:03:17 CST 2017, time=2017-10-30, status=1, ipAttribution=)]
    2017-10-30 yjs木玉

    好好好好好好好好

    0

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