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《2018年加拿大肝病学会指南:慢性丙型肝炎的管理(更新)》摘译

2018-08-07 临床肝胆病杂志.2018.34(8):1644-1648.

2018 年6 月加拿大肝病学会(CASL)发布了《慢性丙型肝炎的管理:2018 年指南更新》。该指南的主要推荐意见与欧洲肝病学会(EASL)及美国肝病学会(AASLD)和美国感染病学会(IDSA)近年发布的相关指南基本一致,同时又具有如下特点:(1)密切结合加拿大HCV 感染流行情况;(2)由于有新证据显示耐药突变检测对特定方案和特定人群是必要的,因此加拿大指南最值得关注的不同是更强调耐药变异检

中文标题:

《2018年加拿大肝病学会指南:慢性丙型肝炎的管理(更新)》摘译

发布机构:

发布日期:

2018-08-07

简要介绍:

2018 年6 月加拿大肝病学会(CASL)发布了《慢性丙型肝炎的管理:2018 年指南更新》。该指南的主要推荐意见与欧洲肝病学会(EASL)及美国肝病学会(AASLD)和美国感染病学会(IDSA)近年发布的相关指南基本一致,同时又具有如下特点:(1)密切结合加拿大HCV 感染流行情况;(2)由于有新证据显示耐药突变检测对特定方案和特定人群是必要的,因此加拿大指南最值得关注的不同是更强调耐药变异检测对选择治疗方案的指导价值;(3)适当拓宽了某些人群的推荐治疗方案。此外,对于有效性和安全性具有相似高质量证据的不同治疗方案,该指南力图做出平等推荐,而不注重其他与疗效和安全性关系不大但可能影响方案选择的因素[例如每日服药粒数带来的负担和药物- 药物间相互作用(drug - drug interac tions,DDIs)等]。另一方面,鉴于方案特异性因素可能成为个体用药选择的主要影响因素,这需要临床医师和患者充分讨论沟通,帮助患者做出适合自身的选择。

译者: 南京中医药大学附属八一医院全军肝病中心 卜凡 侯俊兴(译) 于乐成(审校)

拓展指南:丙型肝炎相关指南:

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    2018-08-17 xiaotao112411

    学习学习学习

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